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Origanum oil emulsion and technique of preparing the same

A preparation process, oil emulsion technology, applied in the direction of emulsion transportation, oil/fat/wax non-active ingredients, etc., can solve the problems of inconvenient application, oregano oil is volatile, unstable, and irritating, and achieves no tolerance Good medicinal properties, good thermal stability, small milk droplet effect

Inactive Publication Date: 2008-02-27
青岛康地恩实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The main purpose of the present invention is to solve the shortcomings of oregano oil that is volatile, unstable, highly irritating, and inconvenient to apply, and provide the market with a stable, efficient, green, safe, non-drug-resistant, non-residual, and easy-to-use New drug preparations for animals

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 1000ml

[0021] Preparation method and steps: Dissolve benzyl alcohol in purified water, add Span 80, Tween 80 and propylene glycol, stir and dissolve to form solution A, add solution A to the colloid mill, adjust the speed to 2000 rpm, stir and mix for 5 minutes ; Dissolve oil-soluble antioxidants BHA and BHT in ethanol, add to oregano oil to become solution B, slowly add liquid B to liquid A in the colloid mill, and emulsify for 30 minutes; then filter and pack to obtain 2% Oregano Oil Emulsion.

Embodiment 2

[0023] 1000ml

[0024] Preparation method and steps: dissolve benzyl alcohol in purified water, add Span 80, Tween 80 and glycerol, stir to dissolve, and form solution A, add solution A to the colloid mill, adjust the speed to 4000 rpm, stir and mix 10 minutes; Dissolve oil-soluble antioxidants BHA and BHT in ethanol, add to oregano oil to form solution B, slowly add solution B to solution A in the colloid mill, and emulsify for 40 minutes; then filter and pack to obtain 5% oregano oil emulsion.

Embodiment 3

[0026] 1000ml

[0027] Preparation method and steps: Dissolve oil-soluble antioxidants BHA and BHT in ethanol, add to oregano oil, then add Span 80, Tween 80 and glycerin, stir and mix evenly to form solution C, add solution C to Colloid mill, adjust the rotation speed to 5000 rpm, stir and mix for 5-10 minutes; dissolve phenol in purified water to become solution D, add solution D to solution C in the colloid mill, and emulsify for 60 minutes; then filter and pack , That is, 8% oregano oil emulsion.

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PUM

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Abstract

The invention discloses a composition of wild marjoram oil emulsion of animal drug and preparing technique, which is characterized by the following: selecting natural wild marjoram oil or synthetic wild marjoram oil as raw material; using non-ion typed surface activator as wild marjoram oil; adopting low-carbon aliphatic alcohol as auxiliary emulsifying agent; making purity water as water phase; adding fitful quantity of preservative and anti-oxidizing agent; emulsifying through emulsion grinding; obtaining the product. The invention has simple technique and stable product without clinical irritation, which is easy to do scale manufacturing with good spreading and applying value.

Description

technical field [0001] The invention relates to an animal medicine oregano oil emulsion for antibacterial, antidiarrheal and growth promoting for livestock and poultry and its preparation process. Background technique [0002] Oregano oil, the extract of natural plant oregano, is a natural antibiotic. Oil of oregano is not pure, but rather a mixture of compounds that contribute to the aroma. The chemical constituents of oregano oil are mainly thymol (Thym01), carvacrol (Carvacr01), γ-terpinene and ρ-cymene. Among them, thymol and carvacrol have the greatest antibacterial activity, and they are the precursors of biosynthesis of thymol and carvacrol, both of which have antimicrobial activity. [0003] Oregano oil has antibacterial and bactericidal functions, and its antibacterial activity is mainly realized through the denaturation and coagulation of bacterial cell wall structural proteins, by changing the H + and K + The high permeability makes the phenols on the cytoplas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/107A61K47/44
Inventor 周玉武徐福亮郝智慧栾明娜
Owner 青岛康地恩实业有限公司
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