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Patrinai villosa tablet and preparation method

A production method and a technology for losing sauce tablets, which are applied in the field of Chinese patent medicine, can solve the problems of poor tablet quality, insufficient hardness, and long tablet disintegration time, and achieve the effects of quick efficacy, overcoming inability to take, and easy absorption.

Inactive Publication Date: 2009-01-14
云南云河药业股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, existing tablets have long disintegration times, insufficient hardness, and poor tablet quality

Method used

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  • Patrinai villosa tablet and preparation method
  • Patrinai villosa tablet and preparation method

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Embodiment Construction

[0023] As mentioned above, 1000 g of the purified Patrinia rhizome and raw medicinal materials were crushed into a 24-mesh coarse powder, added with 60% ethanol, and soaked for 24 hours. Percolate with the same ethanol to obtain the wet liquid. Seep repeatedly until the color fades. Combine the filtrates of each percolation and concentrate them with a tiltable vacuum concentration tank. The steam pressure is controlled below 0.35MPa, the temperature in the pot is ≤70°C, and when it is concentrated to a relative density of 1.35-1.40, it is dried out of the pot. Put the concentrated extract in a tray and dry it in a hot air circulation oven. The drying temperature is 80°C, and the thickness of the tray is 1.50-1.20cm. The dried extract is a block, and it is crushed to 100 mesh with a pulverizer for use. When pulverizing, the temperature in the machine does not exceed 60°C.

[0024] This is followed by wet granulation. The steps are as follows: take all the extract powder an...

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Abstract

The invention relates to a dahurican patrinia tablet and a manufacturing method thereof, which is the rootstalk of Patrinia scabiosaefolia Fisch.ex Trev. that is a valerianaceae plant and an extract tablet of a root. An extract and auxiliary materials are pressed into the tablet and coated with a film. The manufacturing method is as follows: raw medicine materials are grinded; then the raw medicine materials are moistened, soaked and percolated by ethanol until color gets light; percolation solution is concentrated to obtain the extract; the extract is dried and grinded into extract powder; starch is proportionally added and mixed with the extract powder evenly; the starch and the extract powder undergo the processes of damp granulation, drying and finishing; magnesium stearate is added and mixed together; and the extract powder, the starch and the magnesium stearate are made into the tablet by die pressing and coated with the film by a coating machine. The dahurican patrinia tablet has the beneficial effects of improving the structure of a pill flan, substituting the film for sugarcoat and solving problems that a patient suffering diabetic can not take the tablet and the sugar-coat is affected with damp, gets mildew and goes bad easily. Compared with the prior medicine, the quality guarantee period of the medicine is prolonged by over 50 percent. The release time of the tablet is shortened to 10 minutes from 30 to 60 minutes. Therefore, the tablet is absorbed by people more easily and drug action is quicker.

Description

technical field [0001] The invention belongs to a kind of Chinese patent medicine, Paijiang Tablet and a production method thereof. Background technique [0002] Paijiang Tablet is a Chinese patent medicine for treating insomnia. It was first created by the applicant unit. It was recorded in the "National Ministry of Health Drug Standard Traditional Chinese Medicine Prescription Preparation". It has become a well-known prescription in the world and has been widely used. contributed. With the expansion of the user population, some of its problems have also been exposed. The main reason is that the sugar-coated packaging is susceptible to moisture and deterioration, and diabetics cannot take it. Diabetics are also a group with a high incidence of insomnia, and the drug is widely used. In addition, the disintegration time of existing tablets is long, the hardness is insufficient, and the tablet quality is not good. Contents of the invention [0003] The purpose of the pres...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/28A61K47/36A61P25/20A61K125/00
Inventor 刘剑胡松谋
Owner 云南云河药业股份有限公司
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