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Use of Chinese medicinal composition in preparing medicament for treating metabolism syndrome

A technique for metabolic syndrome and composition, which is applied in the application field of medicine, can solve problems such as the application of undisclosed traditional Chinese medicine composition, and achieve the effect of improving impaired glucose tolerance and reducing LDL/HDL

Active Publication Date: 2009-04-22
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two patents do not disclose the application of the traditional Chinese medicine composition in the preparation of drugs for the treatment of metabolic syndrome

Method used

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  • Use of Chinese medicinal composition in preparing medicament for treating metabolism syndrome
  • Use of Chinese medicinal composition in preparing medicament for treating metabolism syndrome
  • Use of Chinese medicinal composition in preparing medicament for treating metabolism syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] a) The raw material drug formula is:

[0057] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0058] Paeoniae Rubra 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 19.8g

[0059] Cicada slough 46.2g centipede 6.6g borneol 33g Suanzaoren (fried) 33g;

[0060] b) Crushing process of medicinal materials:

[0061] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0062] c) Extraction concentration and drying proc...

experiment example

[0069] Therapeutic effect of medicine of the present invention on metabolic syndrome rat model

[0070] 1. Materials and methods

[0071] 1.1 Experimental animals and grouping 32 adult male spontaneously hypertensive rats (SHR) weighing 300-400 g (purchased from Shanghai Slack Experimental Animal Co., Ltd.) were randomly divided into normal food control group (group A), MS model group Control group (group B), low dose of drug treatment group of the present invention (group C) and high dose of drug treatment group of the present invention (group D), and 10 male Wistar rats are general food reference control group (group E) .

[0072] 1.2 Experimental Model Preparation Rats in each group were weighed, blood pressure was measured and blood was taken from the tail vein. Groups A and E were fed with common feed, and groups B-D were fed with high-fat feed containing propylthiouracil (10% lard , 10% sucrose, 4% cholesterol and basal feed, etc.) were fed for 8 weeks, including model...

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Abstract

The invention discloses an application of a Chinese medicine composition to the preparation of a medicine for treating metabolic syndrome. Tests prove that the Chinese medicine composition has effects of reducing the blood sugar of the metabolic syndrome, regulating the blood fat, improving the impaired glucose tolerance and the like, and can also decrease the left ventricular end systolic volume, improve the systolic function of the heart and reduce the thickens of the carotid wall; moreover, while improving the heart function of the patient suffered from the metabolic syndrome, the invention can obviously improve the blood vessel function of the patient suffered from the metabolic syndrome, and has the effect of treating the metabolic syndrome.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the invention relates to an application of a traditional Chinese medicine composition in preparing medicine for treating metabolic syndrome, which belongs to the field of traditional Chinese medicine application. Background technique [0002] Metabolic syndrome (MS) is produced through susceptibility genes under the stimulation of environmental factors, immunity and inflammation. The onset is related to acquired, environmental and genetic factors. However, the etiology is not yet clear and there is a lack of specific treatment . MS has clinical features such as hypertension, hyperglycemia, lipid metabolism disorder, and obesity, and the main feature is insulin resistance (IR). IR and its secondary metabolic disorders are the common soil for coronary heart disease, diabetes and hypertension [Stern. Diabetes and cardiovascular disease: common soil hyp...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P3/06A61P3/10A61P9/12A61K31/045A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 王超
Owner HEBEI YILING MEDICINE INST
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