Benzo (alpha) pyrene removal method from red clover extract using ultramicro communication technique

An ultrafine pulverization technology, red clover technology, applied in the field of traditional Chinese medicine extraction, can solve the problem of low efficiency of benzo[a]pyrene
CN101455708AActive Publication Date: 2009-06-17湖南春光九汇现代中药有限公司

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
湖南春光九汇现代中药有限公司
Publication Date
2009-06-17

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Abstract

The invention discloses a method for eliminating benzo[a] pyrene in red clover extract by ultrafine grinding technology. The method has steps of crushing the red clover extract into granules having grain diameter no more than 75 um by ultrafine grinding, stirring the grinded extract by solvent of acetic ester and petroleum ether having equivalent mass ratio, extracting by hot reflux, drying, and thereby the product is obtained. The invention obviously improves elimination rate for benzo[a] pyrene in red clover extract.
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Description

technical field

[0001] The invention belongs to the technical field of extraction and application of traditional Chinese medicines, and in particular relates to a method for removing benzo[a]pyrene from red clover extract by applying ultrafine pulverization technology. Background technique

[0002] Benzo[a]pyrene, also known as 3,4-benzopyrene. It is a polycyclic aromatic hydrocarbon composed of 5 benzene rings with the molecular formula C 20 h 12 , with a molecular weight of 252. The structural formula is shown in the figure below.

[0003] Benzo[a]pyrene is a light yellow needle crystal at room temperature, which can be divided into monoclinic crystal or orthorhombic crystal. It is stable in nature, with a boiling point of 310-320°C (10mm Hg), a melting point of 179-180°C, and a solubility in water of 0.004~0.012mg / L, easily soluble in cyclohexane, hexane, benzene, toluene, xylene, acetone and other organic solvents, slightly soluble in ethanol and methanol. When benz...

Claims

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