Veramyst medicinal preparation and preparation method
A technology of fluticasone furoate and pharmaceutical preparations, which is applied in the field of medicine and its preparation, and achieves the effects of fast curative effect, high efficiency and small side effects
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Embodiment 1
[0019] Fluticasone furoate gel spray for allergic rhinitis
[0020] prescription:
[0021] Fluticasone furoate 0.05%, gellan gum 0.02%, Tween-803%, methylcellulose 3%, thimerosal 0.01%, glycerin 30%, propylene glycol 10%, and the remaining content is purified water.
[0022] Preparation method:
[0023] 1. Add fluticasone furoate micropowder into Tween-80 aqueous solution to disperse the drug evenly.
[0024] 2. Take another container and add appropriate amount of pure water, add thimerosal and gellan gum successively and stir to dissolve. Then add fluticasone furoate micropowder-Tween-80 aqueous solution, methylcellulose, glycerin, propylene glycol, and purified water to the total amount. Stir well to mix.
[0025] 3. Adjust the pH to 4-7, pack into spray bottles, and perform quality inspection to obtain fluticasone furoate gel spray.
[0026] Effect:
[0027] It is safe and effective to treat perennial and seasonal allergic rhinitis with this product. Through the anti...
Embodiment 2
[0029] Fluticasone furoate liniment for atopic eczema
[0030] prescription:
[0031] A: Phellodendron 50g, Sophora flavescens 65g, Pepper 45g, Gallnut 80g
[0032] B: Fluticasone furoate 1g, Tween-800.05g, ethanol 100g, glycerin 120g, carbomer 3g, purified water to a total of 1000ml.
[0033] Preparation method:
[0034] 1. Decoct the traditional Chinese medicine of group A with 5 times the amount of water twice, each time for 2 hours, combine the filtrates, and precipitate the concentrated solution with 75% ethanol for 18 hours, recover the ethanol until it has no alcohol smell, and obtain the extract of group A for later use.
[0035] 2. Add fluticasone furoate micropowder into Tween-80 aqueous solution to disperse the drug evenly.
[0036] 3. Take another container and add an appropriate amount of pure water, add carbomer and stir to dissolve.
[0037] 4. Add the Tween-80 solution containing fluticasone furoate micropowder into the carbomer solution and stir evenly, th...
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