Medical fiber and manufacturing method thereof

Abstract

The invention relates to a medical fibre and a manufacturing method thereof. The medical fibre has characteristics in composition by weight percent: 59.99-89.9% glutin with average molecular weight 10-20 ten thousands; 1-5% sericin with average molecular weight 1000-40000; 9-35% fibroin with average molecular weight 80-4000; 0.01-0.1% cross linker that is 1-ethide-3, 3-dimethyl aminopropyl-carbodiimide and / or N-hydroxide radical succimide. The method includes steps as follows: placing glutin, sericin and fibroin into distilled water according with weight percent composition, swelling 150-200 miniutes under 70-95 DEG. C for preparing spinning stock solution, reducing temperature to 35-45 DEG. C after filtering and deaeration, adding cross linker and mixing; using centrifugal spinning technique for spinning, drying and forming the obtained fibre rapidly, then placing into a vacuum baking oven for baking further, collecting, packaging, irradiating sterilizing by cobalt 60 gamma, and obtaining the medical fibre.

Description

technical field [0001] The invention relates to a fiber material manufacturing technology, in particular to a natural biological fiber suitable for medical use and a manufacturing method thereof. Background technique [0002] The use of natural biomaterials to manufacture medical fibers has been studied. For example, Chinese patent (application number is 92105622.2) document discloses a kind of with sodium alginate as raw material, with calcium chloride aqueous solution as coagulant, adopts the method for the absorbable hemostatic dressing of wet manufacturing; Chinese patent document (CN 85109219A) Disclosed is a technology for manufacturing medical hemostatic fibers by dry spinning process, the content of gelatin / polyvinyl alcohol (40--65 / 35-60) in the hemostatic fibers is 40-50%, and the rest is mainly soft water; China The patent document (CN 1157355A) discloses a "composition of hemostatic fiber and its spinning process by gas drawing method". The gelatin content in t...

AI Technical Summary

Problems solved by technology

This method takes too long, consumes too much energy, is very inefficient, and has the risk of being unsafe or unhygienic (secondary pollution)

Chinese patent literature (CN1270240A) discloses a hemostatic fiber with gelatin as the main component and comprising polyvinylpyrrolidone, water-soluble chitosan, and sodium alginate, which is spun by a centrifugal spinning process, and the resulting fiber is rapidly dried and formed, and The hemostatic fiber can be directly collected, packaged, and sterilized, but since polyvinylpyrrolidone is a synthetic substance, it is difficult for the human body to degrade it by itself, while chitosan and sodium alginate need special enzymes to degrade it, so the human body degrades it It takes a long time to absorb this kind of substance, and because the fiber-forming time is relatively short, and no cross-linking agent is used, the resulting fiber is easy to stick to hands and stick together, which is not conducive to practical use