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Compound lactobacillus vagina cleaning hygiene body lotion for preventing or treating vaginitis and technology thereof

A kind of technology of compound lactic acid bacteria and nursing solution, applied in vaginal microecological regulator, and the technical field of preparing this preparation

Inactive Publication Date: 2009-09-30
大连润生堂生物科技工程有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dispensing after thorough mixing

Method used

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  • Compound lactobacillus vagina cleaning hygiene body lotion for preventing or treating vaginitis and technology thereof
  • Compound lactobacillus vagina cleaning hygiene body lotion for preventing or treating vaginitis and technology thereof
  • Compound lactobacillus vagina cleaning hygiene body lotion for preventing or treating vaginitis and technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Insert the seed liquid of Lactobacillus delbrueckii strain into the sterilized culture medium containing 3% glucose, 1% soybean peptone, 0.8 yeast extract, 0.8% fish peptone, and 0.4% triammonium citrate , after anaerobic fermentation at 36-39°C, centrifuged to obtain the centrifuged supernatant, namely the fermentation centrifugate. Take 400g of fermented centrifuged liquid and add it to 1000ml with deionized water to form a compound lactic acid bacteria cleansing care solution.

Embodiment 2

[0027] Example 2 Lactobacillus delbrueckii fermentation centrifugal liquid 300g; erythritol 20g; lactic acid 20g; hydrogen peroxide 30g; borneol 3g; peppermint oil 2g; Fully mixed and subpackaged to prepare the complex lactic acid bacteria cleansing and care solution. Wherein the fermentation rationality of Lactobacillus delbrueckii is also prepared as follows: the seed solution of Lactobacillus delbrueckii strain is inserted into sterilized 3% glucose by weight, 0.5% soybean peptone, 0.5% fish peptone, 0.8 % yeast extract and 0.35% triammonium citrate medium, after anaerobic fermentation at 37°C, the bacterial cells were separated by centrifugation to obtain the fermentation centrifugate.

Embodiment 3

[0028] Embodiment 3 A kind of vaginal health care of the present invention or the compound lactobacillus cleaning Yin nursing solution of prevention bacteritis and preparation process are as follows:

[0029] Insert the Lactobacillus delbrueckii strain seed solution into the sterilized culture medium containing 2% glucose, 1% soybean peptone, 0.5% yeast extract, 0.2% sodium acetate, 0.2% triammonium citrate, after 37 After anaerobic fermentation at ℃ for 48 hours, centrifuge and obtain supernatant as fermentation centrifugate. Take 400g of fermentation centrifugal liquid; 20g of erythritol; 20g of lactic acid; 50g of glycerin; 2g of borneol; 3g of peppermint oil; add deionized water to 1000ml. Mix well and dispense. Treat patients suffering from bacterial vaginosis with the compound lactic acid bacteria vaginal cleansing lotion prepared by the method in Example 2. Take 10 ml of this product before going to bed every night and add 5 to 10 times the amount of warm water to dilu...

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Abstract

The invention relates to compound lactobacillus vagina cleaning hygiene body lotion for preventing or treating vaginitis and technology thereof. Strain seed liquid of lactobacillus debrueckii is inoculated with a culture medium containing 1 to 3 weight percent of glucose, 0.5 to 1.5 weight percent of soy peptone, 0.5 to 1 weight percent of yeast extract, 0.5 to 1 weight percent of fish peptone and 0.3 to 0.5 weight percent of tribasic ammonium citrate, after the anaerobic fermentation at the temperature of 36-39 DEG C, 20 to 40 weight percent of centrifugal separating liquid is taken, 1 to 3 percent of phycite, 1 to 3 percent of lactic acid, 1 to 3 percent of peroxide, 0.2 to 0.5 percent of borneol, 1 to 3 percent of peppermint oil and the balance of water can also be taken, and the taken materials and the water are fully mixed together. The metabolites of lactobacillus, such as lactic acid, acetic acid, peroxide, bacteriocin, other volatile fatty acids, useful enzymes, polypeptides and other actives are used for regulating the vaginal dysbacteriosis, effectively inhibiting external-attacking bacteria and few excessively propagating vaginal floras, restoring the natural ability of resisting the disturbance of heterotrophic bacteria of vagina and promotes the biological self-cleaning function of the vagina to prevent and treat bacteritic vaginitis.

Description

Technical field: [0001] The present invention relates to a kind of compound lactic acid bacteria cleansing and nursing solution for preventing or treating vaginitis, a kind of vaginal micro-ecological regulator (disinfectant) for women's vaginal health care and adjustment of vaginal flora imbalance, and a process for preparing the preparation . Background technique: [0002] For healthy women, the vagina has a natural defense function against the invasion of pathogens due to the characteristics of anatomical tissues. For example, the closure of the vaginal opening, the close adhesion of the front and rear walls of the vagina, the proliferation of vaginal epithelial cells under the influence of estrogen, and the keratinization of surface cells, and the pH value of the vagina is kept at pH 4-5, which inhibits the reproduction of pathogens that adapt to alkaline. The cervical mucus is alkaline, which inhibits the reproduction of pathogens adapted to the acidic environment. Whe...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61K36/534A61P15/02A61K31/045A61K31/047A61K31/19A61K33/40A61K35/747
Inventor 袁杰力左振军
Owner 大连润生堂生物科技工程有限公司
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