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Method for producing schisandra extract by adopting high voltage pulse electric field technology

The technology of Schisandra chinensis extract and high voltage pulse is applied in the directions of drug combination, pharmaceutical formulation, plant raw material, etc., which can solve the problems of inability to meet production needs in the pharmaceutical field, high energy consumption and high cost, and achieve novel technology, improve product quality, Guaranteed non-degradable effect

Inactive Publication Date: 2012-04-25
赵景辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, the commonly used methods for extracting active ingredients of Schisandra chinensis include ultrasound, carbon dioxide supercritical extraction, heating and reflux, etc. The yield of Schisandrin is as low as about 0.2-0.5%. The disadvantages are high cost, time-consuming, laborious, and huge energy consumption. Unable to meet the production needs of the pharmaceutical field

Method used

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  • Method for producing schisandra extract by adopting high voltage pulse electric field technology

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Select 10 kg of schisandra chinensis without insects and pollution, crush it to about 100 meshes; add 100 liters of 80% ethanol, stir and mix evenly for soaking; place it for 0.5h and then stir and mix evenly for later use; pump the soaked raw materials continuously into high In the voltage pulse extraction unit, the field strength is 10kv, the number of pulses is 10, and the extraction solution is continuously collected; the extraction solution is pumped into a plate and frame filter for filtration; the filtrate is vacuum concentrated to a liquid extract; the liquid extract is sprayed Dried or freeze-dried into powder, the yield of schisandrin A is 76g.

Embodiment 2

[0026] Crush 10kg of schisandra to 100 mesh, add 12 liters of 70% ethanol extraction solvent to soak; stir and mix the raw material with the extraction solvent, put it aside for 0.5h and then stir and mix well for later use; use a liquid pump to continuously pump the soaked raw material into the In the voltage pulse extraction unit, the field strength is 15kv and the number of pulses is 10, and the extraction solution is continuously collected; the extraction solution is pumped into a plate and frame filter for filtration; the filtrate is vacuum concentrated to a liquid extract; the liquid extract is sprayed Dried or freeze-dried into powder, the yield of schisandrin A is 80g.

Embodiment 3

[0028] Choose 10kg Schisandra chinensis and crush it to about 100 meshes; add the raw materials and 90% ethanol extraction solvent to soak according to material: liquid = 1:14; Continuously pump the soaked raw materials into the high-voltage pulse extraction unit, extract with the parameters of field strength 10kv and pulse number 12, and continuously collect the extract; pump the extract into the plate and frame filter for filtration; vacuum concentrate the filtrate to Fluid extract; the fluid extract is spray-dried or freeze-dried into powder, and the yield of schisandrin A is 85g.

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Abstract

The invention provides a method for producing schisandra extract by adopting high voltage pulse electric field technology. As the high voltage pulse electric field extraction technology is adopted to extract schisandra active ingredients at normal temperature, the raw type state of schisandra is remained to the maximum degree and simultaneously, the product quality and productivity are improved while the production cost is reduced. The process is advanced, the extracting time is short, the technology is novel and the extraction rate is high. The method realizes the integration of normal-temperature extraction and sterilization, guarantees no degradation of thermosensitive substances, continuously and quickly extracts and is energy-saving, environment-friendly and high-efficiency.

Description

Technical field: [0001] The invention relates to a non-thermal and rapid extraction method of schisandra extract, in particular to a method for rapid extraction of schisandra extract by using high-voltage pulse electric field technology, and belongs to the technical field of extracting effective components of Chinese herbal medicines. Background technique: [0002] Schisandra chinensis (Turcz.) Baill] is a perennial woody vine of Magnoliaceae. The fruit is used as medicine, and the roots and stems can also be used as medicine. It has the functions of astringing the lungs, nourishing the kidneys, antiperspirant, raw dregs, antidiarrheal, and astringent essence. Indications for cough and asthma, body fluid deficiency and thirst, spontaneous sweating, nocturnal emission, chronic diarrhea, neurasthenia. Modern studies have proved that it also has the functions of regulating blood pressure, protecting the liver and "adaptogen". It is an authentic northern precious medicinal ma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/57A61P1/12A61P1/16A61P9/00A61P11/06A61P11/14A61P15/00A61P25/20A61P43/00A61K131/00
Inventor 赵景辉王英平鲍成胜程世鹏韩春丽潘永岐赵明忠
Owner 赵景辉
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