Supercharge Your Innovation With Domain-Expert AI Agents!

elderberry spray

A technology of spray and Jieguling, which is applied in the field of pharmaceutical preparations, can solve the problems of high skin irritation, high adhesion, and difficulty in peeling off and sticking, and achieves the effects of no allergic reaction, good air permeability and remarkable curative effect.

Active Publication Date: 2012-02-22
ANHUI ANKE BIOTECHNOLOGY (GRP) CO LTD
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Jieguling plaster is mainly used clinically to treat various closed new fractures, bruises, sprains and other soft tissue injuries, etc., with remarkable curative effect; however, the original dosage form is adhesive plaster, and the disadvantages of this dosage form are small drug load, adhesion, etc. Excessive air permeability, poor air permeability, strong skin irritation, prone to allergic reactions, difficult to peel off, sticky body hair, rubber substrate and gasoline used in production, there are disadvantages such as safety hazards and environmental pollution

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • elderberry spray
  • elderberry spray
  • elderberry spray

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The prescription of Jieguling spray is as follows: Rhizoma Drynariae, Dipsacus, Notopterygium, Angelica, Araceae, Wujiapi, Safflower, Dandelion each 64g, frankincense, myrrh each 21.4g, borneol, eucalyptus oil each 7g, peach kernel 32g, camphor 14g, methyl salicylate 10.5g, ground beetle 43g;

[0034] The above sixteen raw materials, except borneol, camphor, methyl salicylate, and eucalyptus oil, were decocted twice with 8 times the weight of wood beetle and peach kernels, each time for one hour, and the decoction was combined and filtered. After filtering, the filtrate was concentrated into a water-extracted thick paste with a relative density of 1.26g / ml (20°C); Pishiwei crude drug is pulverized into coarse powder, according to the percolation method (appendix I0) under the liquid extract and extract item, with 10 times of its weight, concentration is 90% ethanol as solvent, carries out percolation, collects the percolation liquid , reclaim ethanol, be concentrated t...

Embodiment 2

[0036]According to the prescription among the embodiment 1, add 15 times of its weight water decoction twice to ground beetle, peach kernel, each one hour, merge decoction, filter, and the filtrate is concentrated to relative density and is 1.25g / ml (20 ℃ ) water to extract thick ointment; then the remaining rhizoma drynariae, Dipsacus, Notopterygium, Angelica, Araceae, safflower, dandelion, frankincense, myrrh, Wujiapi Shiwei raw materials are pulverized into coarse powder, and the liquid extract is mixed with The percolation method (appendix I0) under the extract item, use 15 times of its weight, concentration is 90% ethanol as solvent, carry out percolation, collect percolation liquid, reclaim ethanol, be concentrated to relative density and be 1.05g / ml (20 ℃) alcohol-extracting thick cream; the above-mentioned water-extracting thick cream, alcohol-extracting thick cream and borneol, camphor, methyl salicylate, eucalyptus oil are mixed evenly, and then it is dissolved to 100...

Embodiment 3

[0038] According to the prescription among the embodiment 1, add 12 times of its weight water decoction twice to ground beetle, peach kernel, each one hour, merge decoction, filter, and the filtrate is concentrated into relative density and is 1.27g / ml (20 ℃ ) water to extract thick ointment; then the remaining rhizoma drynariae, Dipsacus, Notopterygium, Angelica, Araceae, safflower, dandelion, frankincense, myrrh, Wujiapi Shiwei raw materials are pulverized into coarse powder, and the liquid extract is mixed with The percolation method (appendix I0) under the extract item, with 8 times of its weight, concentration is 90% ethanol as solvent, carries out percolation, collects percolation liquid, reclaims ethanol, concentrates to relative density and is 1.15g / ml (20 ℃) alcohol-extracting thick cream; the above-mentioned water-extracting thick cream, alcohol-extracting thick cream and borneol, camphor, methyl salicylate, eucalyptus oil are mixed evenly, and then it is dissolved to...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of a medicinal preparation, in particular to a bone joiner spray which is prepared by the following steps of: firstly, respectively decocting ground beetles and semen persicae in water respectively, wherein the water is 8 to 15 times the weights of the ground beetles and the semen persicae; merging the decocted solutions, filtering, concentrating the filtrate into aqueous-extraction thickening cream with the relative density of 1.25 to 1.27g / ml for later use; then pulverizing drynaria rhizome, Himalayan teasel root, notopterygium root, Chinese angelica, rhizome arisaematis, safflower, dandelion, frankincense, myrrh and Wu Chia pee into coarse powder, carrying out percolation by taking 95 % alcohol as a solvent, wherein the weight part of the alcohol is 8 to 15 times that of the coarse powder, and collecting a percolated solution, and concentrating the percolated solution into alcohol-extraction thickening cream with the relative density of 1.05 to 1.15g / ml for later use; and finally mixing the aqueous-extraction thickening cream, the alcohol-extraction thickening cream, borneol, camphor, methyl salicylate and eucalyptus oil uniformly, adding 80% alcohol , regulating the pH to 5.5-6.5 by using 4.5 mol / L to 5.5 mol / L NaOH, uniformly stirring and filtering, and then encapsulating the filtered solution. The bone joiner spray of the invention has the advantages of high drug-loading rate, little irritation to skin and convenient use, and meanwhile, because the spray is prepared by finely processing the thickening creams made of raw material when in production, the spray has no pollution to the environment.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a bone-jieguling spray. Background technique [0002] Jieguling plaster is recorded in the thirteenth volume of standard Chinese medicine prescriptions issued by the ministry. It is made of drynaria drynaria, Dipsacus, wood beetle, notopterygium, araceae, frankincense, myrrh, angelica and other traditional Chinese medicines. It has the functions of promoting blood circulation and removing blood stasis. , Shujintongluo, swelling and pain relief effect. [0003] Jieguling plaster is mainly used clinically to treat various closed new fractures, bruises, sprains and other soft tissue injuries, etc., with remarkable curative effect; however, the original dosage form is adhesive plaster, and the disadvantages of this dosage form are small drug load, adhesion, etc. Excessive air permeability, poor air permeability, high skin irritation, prone to allergic reactions, difficult ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8884A61K9/12A61P19/08A61K31/045A61K31/125A61K31/618A61K35/64
Inventor 宋礼华刘道芳王荣海宋社吾谢红星田湘莲
Owner ANHUI ANKE BIOTECHNOLOGY (GRP) CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More