Soft capsule used for clearing away heat and toxic materials and preparation method thereof

Abstract

The invention discloses a soft capsule used for clearing away heat and toxic materials and a preparation method thereof. The soft capsule is prepared by adopting a traditional preparation process after mixing and preparing clear extract powder, vegetable oil, soybean phosphatide and beeswax into suspension. The preparation method of the soft capsule comprises the following steps: decocting coptisroot, rhubarb and baikal skullcap root, preparing a clear paste, then spraying, drying, preparing coptis root powder, rhubarb powder and baikal skullcap root powder and mixing evenly to obtain clear extract powder; mixing the clear extract powder, vegetable oil, soybean phosphatide and beeswax evenly according to the mixture ratio to prepare suspension; and taking gelatin, glycerol and water to prepare gum and then filling and pressing the suspension into the soft capsule. The invention adopts the natural type vegetable oil and the beeswax as a dispersion medium and a suspending agent respectively, enables the medicines to be evenly dispersed, has high utilization degree of the biologic active components of the medicines, enhances the stability of the medicines and the application safety and effectiveness effectively, enshrouds the discomfortable taste of the medicines, is easy to swallow, shortens the disintegration time limit of the soft capsule and enhances the quality standard of the medicines.

Description

technical field [0001] The invention relates to a soft capsule, in particular to a Yiqing soft capsule used for treating mouth and nose sores, sore throat and toothache, dry mouth and tongue and a preparation method thereof. Background technique [0002] The so-called fiery disease in traditional Chinese medicine, that is, "getting angry", is a common disease. This kind of disease is mainly a kind of disease in which the relevant functions of the human body are abnormally excited after the pathogenic factors act on the body. Symptoms include mouth and nose sores, sore throat and toothache, dry mouth, constipation, red and yellow urine and other symptoms. [0003] Yiqing preparation is prepared by extracting Coptidis rhizome, rhubarb and scutellaria baicalensis as the main raw materials. Coptis chinensis has the effects of clearing away heat and dampness, purging fire and detoxifying; Heat-clearing and damp-drying, purging fire and detoxification, hemostasis, the effect of ...

AI Technical Summary

Problems solved by technology

At present, there are granules, hard capsules and soft capsules in Yiqing preparations. The granules are inconvenient to take, and the taste of the hard capsules is not good, and the bioactive ingredients in the granules or hard capsules have low availability, poor sealing performance, and inaccurate content, etc. ; At the same time, the current granule quality standard only uses the chemical reference substance as a contrast in the identification item, and no contrast medicinal material as a contrast, which lacks specificity; the content determination does not have the content determination index of the Chinese monarch drug Coptidis Rhizome, so it is difficult to effectively carry out the quality of the preparation. Although soft capsules have high bioactive ingredient availability and tightness, chemical excipients are used in the dispersion medium or suspending agent, mainly polyethylene glycols, such as PEG-400, PEG-4000, PEG-6000, etc., are easy to cause harm to the human body and reduce the safety and reliability of medication