Surgical repairing patch

A patch and surgical technology, applied in the field of biomedical materials, can solve problems such as troublesome patch placement and potential infection, and achieve the effect of reducing pain and improving affinity

Active Publication Date: 2010-07-14
博迈医疗科技(常州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the actual application of this kind of non-absorbable polymer materials, there are troubles in the placement of the patch during the operation and the possibility of potential infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The synthetic polymer materials are polylactic acid (PLA), polyvinyl alcohol (PVA), polyethylene oxide (PEO), polycaprolactone (PCL), polylactic acid-glycolic acid (PLGA) or their mixtures by electrospinning It can be made into a sheet material of required shape with a thickness of 0.6-1.2 mm. The hyaluronic acid solution with a concentration of 1-3% is evenly sprayed on the above-mentioned sheet-shaped material through a spray gun, with a thickness of 2-15 microns, and the surgical patch material of the present invention is obtained after drying.

Embodiment 2

[0023] The synthetic polymer materials are polylactic acid (PLA), polyvinyl alcohol (PVA), polyethylene oxide (PEO), polycaprolactone (PCL), polylactic acid-glycolic acid (PLGA) or their mixtures by electrospinning It can be made into a sheet material of required shape with a thickness of 0.6-1.2 mm. After mixing the hyaluronic acid solution with a concentration of 1-3% and the collagen solution with a concentration of 1-2%, spray it evenly on the above-mentioned sheet material through a spray gun, with a thickness of 2-15 microns, and obtain the surgical treatment of the present invention after drying. Use patch material.

Embodiment 3

[0025] The artificially synthesized polymer material is polyethylene, polypropylene, polytetrafluoroethylene or a mixture thereof, which is made into sheet-like material with a thickness of 0.4-1 mm and a desired shape through a monofilament weaving method. The hyaluronic acid solution with a concentration of 1-3% is evenly sprayed on the sheet material through a spray gun, the thickness is controlled at 2-15 microns, and the surgical patch material of the present invention is obtained after drying.

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Abstract

The invention provides a tissue repairing patch, which is formed by applying hyaluronic acid film or mixture film of hyaluronic acid and collagen on the surface of high polymer surgical biological patch. The high polymer surgical biological patch is made of artificially synthesized high polymer material. The high polymer surgical biological patch can be prepared by electrostatic spinning process or monofilament spinning process. The patch has improved affinity between biocompatibility and tissue without influencing other biological and mechanical properties and has antibiotic property simultaneously. In addition, filmed-coated patch reduces tissue adhesion and cavum pelvis pain. Moreover, the surgical biological patch has no cytotoxicity and can not cause harm to human bodies.

Description

Technical field: [0001] The invention belongs to biomedical materials, and in particular relates to a biological patch material which can be used for repairing defective tissues or organs in various surgical operations. Background technique: [0002] The application of artificial materials in surgical minimally invasive repair has become the mainstream of modern surgical development. At present, there are mainly two categories of artificial biomaterials and biomaterials. Artificial biomaterials are mainly polymers: such as polyester, carbon fiber, polyethylene, polypropylene, polytetrafluoroethylene, polylactic acid, polyvinyl alcohol, polyethylene oxide, polycaprolactone, and polylactic acid-glycolic acid; Sources of biological materials include: human dermis, animal membrane tissue, animal dermis, etc. Although the selection of materials is diversified and certain effects have been achieved in practical applications, there are still various problems. At present, efforts ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/44A61L27/34A61L27/22A61L27/20A61L27/18A61L27/16
Inventor 苑国忠
Owner 博迈医疗科技(常州)有限公司
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