Stable lenalidomide oral solid preparation
A technology of lenalidomide and solid preparations, which is applied in the field of pharmaceutical preparations, can solve the problems of changing appearance and color, affecting the stability of preparations, and increasing the impurity content of solid oral preparations, achieving improved stability, low impurity content, and high solubility Effect
Active Publication Date: 2010-08-04
NANJING CAVENDISH BIO ENG TECH +1
4 Cites 20 Cited by
AI-Extracted Technical Summary
Problems solved by technology
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreAbstract
The invention discloses a lenalidomide oral solid preparation which is based on 10000 solid preparation units and is prepared by the following components: 10-500g of lenalidomide, 300-1200g of premixed powder, 50-200g of cross-linked sodium carboxymethyl cellulose, 1-50g of magnesium stearate and 100-500ml of 10% (percent weight in volume) povidone absolute ethyl alcohol solution, wherein the premixed powder is the mixture of lactose and microcrystalline cellulose which have the weight ratio of 2:3. In addition, the invention also discloses a preparation method of the lenalidomide oral solid preparation and usage thereof. The lenalidomide oral solid preparation has the advantages that a sample can be reserved for a long time with stable quality; and the lenalidomide oral solid preparation can be released within a short time so as to be easily absorbed by the human body completely.
Application Domain
Technology Topic
Image
Examples
- Experimental program(4)
- Comparison scheme(2)
- Effect test(1)
Example Embodiment
Example Embodiment
Example Embodiment
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more PUM


Description & Claims & Application Information
We can also present the details of the Description, Claims and Application information to help users get a comprehensive understanding of the technical details of the patent, such as background art, summary of invention, brief description of drawings, description of embodiments, and other original content. On the other hand, users can also determine the specific scope of protection of the technology through the list of claims; as well as understand the changes in the life cycle of the technology with the presentation of the patent timeline. Login to view more.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more Similar technology patents
Endogenous perfume from tobacco as well as preparation method and application thereof
ActiveCN102161935AImprove solubilityChen Yanxiang ImprovementTobacco preparationEssential-oils/perfumesMouthfeelTobacco leaf
Owner:CHINA TOBACCO GUANGDONG IND
Nimodipine emulsion injection liquid and method for preparing the same
InactiveCN1732936AImprove solubilityEasy to store and useOrganic active ingredientsNervous disorderSolventEmulsion
Owner:SHANGHAI INST OF PHARMA IND +1
New compound ramification of garcinia acid
InactiveCN1563014AImprove stabilityImprove solubilityOrganic chemistryNitro compound active ingredientsChemistryAcid derivative
Owner:HANGZHOU MINSHENG PHARM CO LTD
New technique for preparing cellulose carbate through urea embedding method
Owner:XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
Nanometer miconazole nitrate emulsion medicine and its prepn process
InactiveCN1931164AImprove solubilityImprove bioavailabilityOrganic active ingredientsAntimycoticsPolymer chemistryOil phase
Owner:NORTHWEST A & F UNIV
Classification and recommendation of technical efficacy words
- Low impurity content
- Improve solubility
Method of forming a dielectric layer and method of manufacturing a semiconductor device using the same
InactiveUS20110159680A1Low impurity contentExcellent shrinkage and etch propertySolid-state devicesSemiconductor/solid-state device manufacturingOxideSemiconductor
Owner:SAMSUNG ELECTRONICS CO LTD
Method for preparing grapheme transparent conducting films by electrophoretic deposition
InactiveCN102877109ALow impurity contentGood electrical conductivity and light transmissionElectrophoretic coatingsThin membraneChemistry
Owner:SICHUAN UNIV
Foundry waste sand regeneration and reuse method and device
ActiveCN103406490ALow impurity contentReduce workloadMould handling/dressing devicesMagnetic separatorIon
Owner:广西兰科资源再生利用有限公司
Method for extracting high-purity steviol glycosides from stevia rebaudiana
ActiveCN105294790ALow impurity contentIncrease leachingSugar derivativesSugar derivatives preparationEthyl esterNanofiltration
Owner:HUNAN HUACHENG BIOTECH
Method for preparing gasoline and diesel by oil washing hydrogenation
InactiveCN101486926ABig increaseLow impurity contentRefining to eliminate hetero atomsCoal tarNaphtha
Owner:胜帮科技股份有限公司