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Oral composition and method of improving astringency of oral composition

A composition and astringent technology, which can be used in oral care, pharmaceutical formulations, and cosmetic preparations. It can solve the problems of temporary astringency, poor persistence, and enhanced metallic taste, and achieve high astringent effects. It is safe and easy to use. excellent effect

Active Publication Date: 2010-08-11
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, oral compositions mixed with polyvalent metal compounds have the problems of being difficult to use in the oral cavity due to the generation of a metallic taste derived from polyvalent metals, and their astringent properties are temporary and poor in durability.
[0005] In order to solve such a problem, for example, in Patent Document 1 (Japanese Patent Application Laid-Open No. 61-186307 ), it is proposed to make astringent by mixing sodium carboxymethylcellulose or sodium alginate in an oral composition containing aluminum lactate. However, at this time, not only the metallic taste in use is also enhanced, it is difficult to use, but also it is difficult to continuously exert excellent astringent properties
[0006] It is effective to mix astringent ingredients in the oral composition as a prevention and improvement of periodontal disease, but it is difficult to obtain a sustained effect in the oral cavity with the prior art Oral composition with high astringency and good texture

Method used

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Experimental program
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Effect test

Embodiment

[0047] Hereinafter, the present invention will be described in more detail by showing experimental examples, examples, and comparative examples, but the present invention is not limited by the following examples. In addition, in the following examples, the compounding quantity is all mass %.

experiment example

[0049] A toothpaste composition (toothpaste) having the composition shown in Table 1 was prepared, and the following evaluations were performed. The results are shown in Table 1.

[0050] (1) Preparation of test toothpaste composition

[0051] Prepare the toothpaste composition of the composition shown in Table 1 by the following method, the innermost layer is made of linear low-density polyethylene with a diameter of 26 mm and a laminated tube with a diameter of 8 mm (low-density polyethylene 72 μm / ethylene acrylic acid copolymer Resin 90 μm / aluminum 10 μm / ethylene-acrylic acid copolymer resin 35 μm / linear low-density polyethylene 50 μm, thickness 257 μm (manufactured by Dainippon Printing Co., Ltd.) was filled with 50 g.

[0052] The toothpaste composition was prepared by using aluminum potassium sulfate (potassium alum, Daemyung Chemical Industry Co., Ltd.), dry aluminum potassium sulfate (burning alum, Daemyung Chemical Industry Co., Ltd.), aluminum ammonium sulfate (ammo...

Embodiment 8

[0079] [Example 8] Toothpaste

[0080] Potassium Aluminum Sulfate 1.0%

[0081] Sodium chloride 5.0

[0082] Isopropylmethylphenol 0.1

[0083] Sodium lauroyl sarcosinate 0.2

[0084]Tocopheryl acetate 0.1

[0085] Sodium Lauryl Sulfate 1.0

[0086] Spice 1.2

[0087] 2,4,4'-Trichloro-2'-hydroxydiphenyl ether (triclosan) 0.03

[0088] Polyoxyethylene (20) hardened castor oil 1.8

[0089] Silicic anhydride 20

[0090] Sodium polyacrylate 0.8

[0091] Xanthane gum 0.5

[0092] Sorbitol liquid (70%) 35

[0093] Sodium saccharin 0.2

[0094] Propylene Glycol 3.0

[0095] Methylparaben 0.05

[0096] Butyl p-hydroxybenzoate 0.01

[0097] Titanium oxide 0.4

[0098] Sodium fluoride 0.21

[0099] water remaining

[0100]

[0101] Total 100.0%

[0102] The mass ratio of sodium chloride / potassium aluminum sulfate: 5.0

[0103] [table 3]

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PUM

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Abstract

One or more aluminum compounds (a) selected among potassium aluminum sulfate, anhydrous potassium aluminum sulfate, and ammonium aluminum sulfate and sodium chloride (b) are incorporated into an oral composition, the amount of the ingredient (a) being 0.2-3 mass%. By the method of improving the astringency of an oral composition, an oral composition can be obtained which has a high astringent effect in the oral cavity at the time of use and retains therein the high astringent effect even after use. This oral composition does not have a metallic taste attributable to a polyvalent metal, and has excellent suitability for use and satisfactory safety.

Description

technical field [0001] The present invention relates to a composition for oral cavity and a method for improving the astringent properties of the composition for oral cavity. The composition for oral cavity exhibits a high astringent effect when used in the oral cavity, and the sustained astringent effect after use is also excellent without feeling It has a metallic taste derived from polyvalent metals, is easy to use, and has an excellent tightening effect on the neck of the teeth, which is effective for the prevention or improvement of periodontal disease. Background technique [0002] Symptoms of periodontal disease patients that have increased in recent years include dental neck pain caused by bacterial infections mainly including obligate anaerobic Gram-negative bacilli such as Porphyromonas gingivalis (P.gingivalis). Pain and redness. Therefore, as an effective means for preventing and improving such periodontal diseases, it is considered that the tightening of the or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/20A61K8/26A61Q11/00
CPCA61Q11/00A61K8/26
Inventor 荒井将人饭泉刚太郎宇野大介
Owner LION CORP
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