A pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate

An insulin-stimulating and peptide-releasing technology, which is applied in drug combinations, active ingredients of artificially synthesized polymer materials, and metabolic diseases, can solve problems such as unrevealed efficacy and patient difficulties, and achieve the effects of inhibiting food intake and reducing body fat
CN101878036AActive Publication Date: 2010-11-03HANMI SCI CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HANMI SCI CO LTD
Publication Date
2010-11-03

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Abstract

The present invention relates to a composition for treating obesity-related diseases comprising an insulinotropic peptide conjugate, more particularly, to a composition for treating obesity-related diseases comprising a conjugate prepared by covalently linking the insulinotropic peptide with a carrier substance via a non-peptidyl linker, and a method for treating obesity-related diseases by using the same. In particular, the composition for treating obesity-related diseases according to the present invention remarkably improves the efficacy of suppressing food intake and its duration to reduce body weight and body fat, thereby being useful for the treatment of obesity-related diseases.
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Description

technical field

[0001] The present invention relates to a composition for treating obesity-related diseases comprising an insulin-stimulating peptide conjugate, in particular to a combination for treating obesity-related diseases comprising a conjugate prepared by covalently linking insulin-stimulating peptide and a carrier substance through a non-peptidyl linker Compositions, and methods of using the compositions to treat obesity-related diseases. Background technique

[0002] Obesity is a chronic disease associated with high morbidity and mortality, resulting from the accumulation of adipose tissue due to energy imbalance or overnutrition. Obesity and obesity-related diseases are serious health problems in the United States and around the world. Over the past 7 years, the prevalence of obesity has increased from 22.9% to 30.6% in the general population of the United States. According to the results of the 1999-2002 National Health and Nutrition Examination Survey (NHANES...

Claims

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