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Composition for preventing and treating allergic rhinitis and preparation method thereof

A technology for allergic rhinitis and composition, which is applied in the field of composition for preventing and treating allergic rhinitis and its preparation, which can solve problems such as inability to treat allergic rhinitis, and achieve the prevention of further exacerbation of the disease, increasing the amount of addition, and runny nose symptoms disappearing effect

Active Publication Date: 2012-07-25
SAIKE SAISI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The weak point of this invention is that it can only prevent but not treat allergic rhinitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Measure 9ml of Goose Bubivorous volatile oil and 1ml of peppermint oil, mix well, and set aside; weigh 80g of β-cyclodextrin and add it to 800ml of water, stir and suspend, heat to 65°C, the solution gradually becomes clear, cool down to 40°C, and slowly Add the above mixed oil dropwise. After the dropwise addition, keep warm at 40°C and stir for 2 hours for clathrate. After inclusion, put it in a refrigerator at 4°C, cool down for about 20 hours, and white powder precipitates. Suction filtration, wash the precipitate with water 3 times, 100ml each time, and then wash 3 times with absolute ethanol, 100ml each time, and dry in an oven at 40°C for 4 hours to obtain 55g of clathrate.

[0056] Determination of oil content of inclusion compound: Weigh 5.0g of inclusion compound, weigh it accurately, put it in a 500ml round bottom flask, add 300ml of water and a few glass beads, shake well, connect it to a volatile oil detector, and measure it according to the method of volat...

Embodiment 2

[0059] Weigh 50g of naphthenic rubber oil and 12.5g of Vaseline, add them into a beaker, heat to 110°C to melt, stir for 30min, filter with a 120-mesh copper wire screen to remove impurities, cool to 60°C, add the clathrate of Example 1 Compound 37.5g, 0.2g sodium bisulfite, continue to stir until condensation, that is.

Embodiment 3

[0061] Weigh 12g of solid paraffin and 87.775g of liquid paraffin, add them to a beaker, heat to 110°C to melt, stir for 30min, filter through a 120-mesh copper wire screen to remove impurities, cool to 60°C, add 0.125 g, 0.1g sodium metabisulfite, continue to stir until it condenses, that is, too.

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Abstract

The invention discloses a composition for preventing and treating allergic rhinitis and a preparation method thereof. The composition comprises an active ingredient and an excipient with high adsorbability, wherein the active ingredient is volatile oil (ml) which accounts for 0.01 to 3 percent of the total weight (g); the balance is the excipient; the volatile oil is one or more of Centipeda minima volatile oil, dementholized peppermint oil, Magnolia biondii Pamp volatile oil and dahurian angelica root volatile oil; and the excipient is two or more of vaseline, white oil, solid paraffin, liquid paraffin, microcrystalline wax, earth wax and naphthenic base rubber oil. The invention also discloses a preparation method for the composition. The method is easy to implement; and the prepared composition has good curative effect. The components of the composition are cheap and readily available, do not have dependency or toxic or side effect, and are safe and reliable; and the prepared composition can block allergen and prevent the state of illness from further intensifying, also can treat rhinitis effectively, and has short treatment time without relapse.

Description

technical field [0001] The invention relates to a composition for preventing and treating rhinitis and a preparation method thereof, in particular to a composition for preventing and treating allergic rhinitis and a preparation method thereof. Background technique [0002] Allergic rhinitis (allergic rhinitis) is a disease that inhales external allergic antigens and causes nasal itching, sneezing, and runny nose as the main symptoms. The disease is caused by two basic factors: ①hereditary allergies; ②repeated exposure and inhalation of external allergens. The inhaled antigens that cause this disease include dust mites, house dust, animal dander, wind pollen of various trees and grasses, etc. Most of these antigens have relatively large particles (5-25 μm), so they can be blocked in the nose Come down and take place immediate (type I) allergic reaction in nasal cavity, cause a series of manifestations such as nasal mucosa congestion, edema and secretion increase, and its imm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/575A61K47/44A61P11/02A61P37/08A61K47/06
Inventor 左立
Owner SAIKE SAISI BIOTECH CO LTD
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