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Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof

A compound chicken and chewable tablet technology is applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., to achieve advanced technology, unique dosage forms, and the effect of treating anorexia in children

Active Publication Date: 2011-07-27
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is inconvenient to divide the doses of powders, and it is difficult to accept tablets for children, and the taste of powders and tablets is very bad, and patients, especially children, have poor compliance and often refuse to take them, which will not achieve the original therapeutic effect

Method used

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  • Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof
  • Pediatric compound chicken's gizzard-membrane chewable tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The present embodiment prepares children's compound chicken Neijin chewable tablets, using the following components:

[0045] Chicken Neijin 85g

[0046] Six Divine Comedies 165g

[0047] Cane sugar 280g

[0048] Mannitol 640g

[0049] Citric acid 12g

[0050] Flavor (strawberry flavor) 4g

[0051] Color (milk chocolate brown) 6.25g

[0052] 2% Sodium Carboxymethyl Cellulose 125ml

[0053] Magnesium Stearate 12g

[0054] 1000 pieces in total

[0055] The preparation technology of the present embodiment:

[0056] The above-mentioned chicken Neijin, Liushenqu and sucrose were pulverized respectively, and after passing through the No. 5 sieve, mixed uniformly; the citric acid was pulverized and passed through the No. 5 sieve, mixed with the above-mentioned fine powder by an equal increment method, and mixed with the above-mentioned fine powder containing 6.25g of pigment (milk). About 125 ml of 2% sodium carboxymethyl cellulose solution in chocolate brown) is used a...

Embodiment 2

[0058] The present embodiment prepares children's compound chicken Neijin chewable tablets, using the following components:

[0059] Chicken Neijin 80g

[0060] Six Divine Comedies 160g

[0061] Cane sugar 240g

[0062] Mannitol 600g

[0063] Citric acid 10g

[0064] Flavor (strawberry flavor) 3g

[0065] Color (milk chocolate brown) 6g

[0066] 2% Sodium Carboxymethyl Cellulose 100ml

[0067] Magnesium Stearate 10g

[0068] 1000 pieces in total

[0069] The preparation technology of the present embodiment:

[0070] Pulverize above-mentioned Jin Nei Jin, Liushenqu and sucrose respectively, pass through No. 5 sieve, mix well; citric acid is pulverized and pass through No. 5 sieve, mix with the above-mentioned fine powder with equal increment method, and use a color containing 6g of pigment (milk chocolate). Brown) about 100ml of 2% sodium carboxymethyl cellulose solution as a binder to make soft material, granulated with 18 mesh sieve, air-dried at 60°C, granulated wit...

Embodiment 3

[0072] The present embodiment prepares children's compound chicken Neijin chewable tablets, using the following components:

[0073] Chicken Neijin 90g

[0074] Six Divine Comedies 170g

[0075] Cane sugar 320g

[0076] Mannitol 680g

[0077] Citric acid 14g

[0078] Flavor (strawberry flavor) 5g

[0079] Color (milk chocolate brown) 6.50g

[0080] 2% Sodium Carboxymethyl Cellulose 150ml

[0081] Magnesium Stearate 14g

[0082] 1000 pieces in total

[0083] The preparation technology of the present embodiment:

[0084] The above-mentioned chicken Neijin, Liushenqu, and sucrose were pulverized respectively, and after passing through the No. 5 sieve, mixed well; the citric acid was pulverized and passed through the No. 5 sieve, mixed with the above-mentioned fine powder by an equal increment method, and mixed with the above-mentioned fine powder containing 6.5g of pigment (milk). About 150 ml of 2% sodium carboxymethyl cellulose solution in chocolate brown) is used as a...

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Abstract

The invention belongs to the field of Chinese patent medicine preparations and relates to pediatric compound chicken's gizzard-membrane chewable tablets and a preparation method thereof. The pediatric compound chicken's gizzard-membrane chewable tablets comprise the following components in parts by weight: 80-90 parts of chicken's gizzard-membrane, 160-170 parts of medicated leaven, 240-320 partsof first filler, 600-680 parts of second filler, 10-14 parts of flavoring agent, 3-5 parts of fragrance, 6-6.5 parts of pigments, 10-14 parts of lubricant and an appropriate amount of binding agent. The pediatric compound chicken's gizzard-membrane chewable tablets have the advantages of significantly improving the bioavailability and the efficacy, being easily absorbed, having rapid onset of action and being easy to be accepted by children.

Description

technical field [0001] The invention belongs to the field of Chinese patent medicine preparations, and relates to a Chinese patent medicine chewable tablet and a preparation process thereof, in particular to a children's compound Ji Nei Jin chewable tablet and a preparation process thereof. Background technique [0002] Anorexia in children is a common disease in pediatrics. Its incidence rate is relatively high, which affects the normal development and healthy growth of children. It has been widely concerned by the society and the medical field, and the demand for its therapeutic drugs is also increasing. In recent years, there have been many domestic researches on the treatment of anorexia in children, but there is currently a lack of effective western medicines in clinical practice, and there is also a lack of Chinese patent medicines for children with spleen-stomach disharmony and spleen dysfunction syndrome, which account for the majority of children with anorexia. eff...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/00A61K47/38A61P1/14A61K35/37A61K35/57
Inventor 江鸿
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD