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A kind of Sanhuang antipruritic liniment and preparation method thereof

A technology for relieving itching and treats, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as discomfort and adverse reactions, and achieve the effect of low price and safe use.

Inactive Publication Date: 2011-11-30
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used external medicines for the treatment of eczema and dermatitis include topical glucocorticoid paste or 25% to 40% zinc oxide oil or paste (generally made by hospitals); most of the products on the market are ointments, and long-term use of hormone ointment is easy. Produce various adverse reactions, and it is not suitable for those with exudation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The composition and dosage of raw materials are: Sophora flavescens 25g, Rhubarb 25g, Scutellaria baicalensis 25g, Cortex Phellodendri 25g.

[0016] Mix and pulverize the above-mentioned raw materials into fine powder according to the above-mentioned parts by weight, pass through an 80-mesh sieve, and mix well; add 5 g of fully swollen sodium carboxymethyl cellulose, add 10 g of melted phenol, stir well, add water Adjust the total amount to 1000ml.

[0017] The using method of liniment described in the present embodiment is as follows:

[0018] The liniment that adopts above-mentioned preparation method to make is divided into bottles by 100 ml / bottle. Apply topically, once a night, shake well before use. 2 weeks is a course of treatment.

Embodiment 2

[0019] Embodiment 2: The difference between this embodiment and Embodiment 1 is the difference in the composition of the crude drug. This embodiment is aimed at patients with acne symptoms.

[0020] Composition of raw materials: Sophora flavescens 25g, rhubarb 25g, skullcap baicalensis 25g, cork phellodendron 25g, hedyotis 30g, dandelion 30g. 2 weeks is a course of treatment.

[0021] Symptoms of acne: facial pimples, blackheads, pustules, nodules, and cysts in severe cases.

[0022] The following is a report of clinical application of the present embodiment and the comparison group: twenty patients in each group.

[0023] group Treatment time (weeks) Clinically cured (example) Get better (example) unhealed (example) Retinoic acid group 2 1 3 16 Retinoic acid group 4 4 4 12 Example set 2 0 6 14 Example set 4 8 8 4 Example two groups 2 4 6 10 Example two groups 4 12 4 4

[0024] Referring to the "Diagno...

Embodiment 3

[0029] Embodiment 3: The difference between this embodiment and Embodiment 1 is the difference in the composition of the crude drug. This embodiment is aimed at patients with rosacea symptoms.

[0030] Composition of raw materials: Sophora flavescens 25g, rhubarb 25g, scutellaria baicalensis 25g, Phellodendron cortex 25g, Shengdi 30, Morus alba 30. 2 weeks is a course of treatment.

[0031] Symptoms of rosacea: nasal flushing, obvious when emotional, papules, pustules, telangiectasia, skin hypertrophy, and finally rhinophyma.

[0032] The following is a report of clinical application of the present embodiment and the comparison group: twenty patients in each group.

[0033] group Treatment time (weeks) Clinically cured (example) Get better (example) unhealed (example) Compound sulfur lotion or 5% sulfur ointment 2 0 2 18 Compound sulfur lotion or 5% sulfur ointment 4 2 6 12 Example set 2 0 8 12 Example set 4 4 12 4 Exam...

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PUM

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Abstract

The invention relates to an external-use liniment of a pharmaceutical composition and a preparation method thereof, and specifically relates to a Sanhuang antipruritic liniment and its preparation method. Calculated by 1000 total weight account, the liniment provided by the invention comprises the following raw medicines of: by weight, 20-30 parts of sophora flavescens, 20-30 parts of rheum officinale, 20-30 parts of Baikal Skullcap Root, and 20-30 parts of Cortex Phellodendri. The preparation method provided by the invention comprises the following steps of: mixing the above raw medicines according to the above weight portions, crushing to fine powders, sieving through a sieve and mixing uniformly; adding 3-10 parts of fully swelled carboxymethylcellulose sodium, adding 5-15 parts of melted phenol, uniformly stirring, and adjusting the total amount to 1000 weight portions by adding water. The Sanhuang antipruritic liniment provided by the invention has functions of clearing heat, detoxifying, inducing astringency and relieving itching, can be used to treat skin diseases such as skin redness, hot itching and exudation in the acute phase due to the toxic heat of the skin, has not only a heat-clearing effect but also a convergence effect, and is suitable for various skin injuries with a few exudation in the acute phase; in addition, the Sanhuang antipruritic liniment is a pure traditional Chinese medicinal preparation, is safe to use with no stimulation, can be used for a long time, and has a low price.

Description

technical field [0001] The invention relates to a liniment for external use of a pharmaceutical composition and a preparation method thereof, in particular to a sanhuang antipruritic liniment and a preparation method thereof. Background technique [0002] At present, for acne, rosacea, furunculosis, eczema, dermatitis (acute phase with mild exudation), herpes zoster (acute phase with blisters), the following drugs are usually used for treatment, such as Commonly used external medicines for treating acne include: 1. Retinoic acid: such as retinoic acid cream (15-20 yuan), retinoic acid gel (35 yuan), isotretinoin gel (more than 50 yuan), etc. , but mild irritation (such as local flushing, desquamation or burning sensation) may occur after administration. 2. Antibiotics: such as 1% to 2% erythromycin ointment (1 to 2 yuan), lincomycin VB6 ointment (about 30 yuan), suitable for infected rashes. The effects of these two types of drugs are limited, and some patients feel discom...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P17/04
Inventor 顾乃芳蔡希吴怡峰傅燕华卞青
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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