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Medicine for reducing serum uric acid, preparation method thereof and purpose thereof

A blood uric acid and drug technology, applied in the field of blood uric acid lowering drugs and their preparation, can solve the problems of repeated blood lipids, affecting the quality of life of patients, and high potential risks, and achieves inhibition of steatosis, protection of liver cells, and good clinical efficacy. Effect

Active Publication Date: 2012-01-11
CHIATAI QINGCHUNBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Hyperuricemia is a group of diseases caused by purine metabolism disorder or decreased excretion of uric acid. Clinically asymptomatic hyperuricemia is very common. If hyperuricemia cannot be controlled in time, urates will be deposited in the kidneys. Or joints and other tissues, causing pathological changes, is the inducing factor of gout, diabetes, coronary heart disease and other peripheral vascular diseases, the potential risk is very high, seriously affects the quality of life of patients, increases the medical burden, most of the clinical treatment of hyperuricemia All chemical synthetic drugs have certain toxicity and side effects, and the abnormality reappears after stopping the drug.
At the same time, the incidence of hyperuricemia and hyperlipidemia caused by a high-purine and high-fat diet also showed a significant upward trend. Although blood lipid regulating drugs have good curative effects, there are blood lipid recurrences after drug withdrawal, or varying degrees. Side effects, high price, etc.

Method used

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  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof
  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof
  • Medicine for reducing serum uric acid, preparation method thereof and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of the pharmaceutical granules of the present invention.

[0026] 【Prescription】 Mushroom 167g, Poria cocos 1000g, Mulberry parasite 500g, Salvia miltiorrhiza 500g

[0027] Astragalus 500g, Coix Seed 1000g, Qinjing 333g

[0028] 【Preparation】

[0029] A. Take Guangcigu, Tuckahoe, Mulberry parasitic, Sheng Astragalus, Salvia miltiorrhiza, Miren, and Qinjie for use according to the prescription scale;

[0030] B. Put the crude drug into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and the temperature in the tank reaches 100 ℃ to start timing; the temperature in the tank drops to 70 ℃ to filter to obtain filtrate I, which is added 8 times. Decoct with water for 1.5 hours, obtain filtrate II according to the method of obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifuge at a centrifugal speed of 3000 rpm and a centrifugation time of 20 min;

[0031]...

Embodiment 2

[0043] Preparation of the pharmaceutical tablet of the present invention.

[0044] 【Prescription】Mushroom 167g, Poria cocos 1000g, Mulberry parasitic 500g, Salvia miltiorrhiza 500g

[0045] Astragalus 500g, Coix Seed 1000g, Qinjing 333g

[0046] 【Preparation】

[0047] A. Take Guangcigu, Tuckahoe, Mulberry parasitic, Sheng Astragalus, Salvia miltiorrhiza, Miren, and Qinjie for use according to the prescription scale;

[0048] B. Put the crude drug into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and the temperature in the tank reaches 100 ℃ to start timing; the temperature in the tank drops to 70 ℃ to filter to obtain filtrate I, which is added 8 times. Decoct with water for 1.5 hours, obtain filtrate II according to the method of obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifuge at a centrifugal speed of 3000 rpm and a centrifugation time of 20 min;

[0049] C. The...

Embodiment 3

[0054] Preparation of the pharmaceutical capsule of the present invention

[0055] 【Prescription】Mushroom 167g, Poria cocos 1000g, Mulberry parasitic 500g, Salvia miltiorrhiza 500g

[0056] Astragalus 500g, Coix Seed 1000g, Qinjing 333g

[0057] 【Preparation】

[0058] A. Take Guangcigu, Tuckahoe, Mulberry parasitic, Sheng Astragalus, Salvia miltiorrhiza, Miren, and Qinjie for use according to the prescription scale;

[0059] B. Put the crude drug into the extraction tank, add 8 times the amount of water, heat and decoct for 1.5 hours, and the temperature in the tank reaches 100 ℃ to start timing; the temperature in the tank drops to 70 ℃ to filter to obtain filtrate I, which is added 8 times. Decoct with water for 1.5 hours, obtain filtrate II according to the method of obtaining filtrate I, combine filtrate I and filtrate II, and centrifuge at room temperature to obtain centrifuge at a centrifugal speed of 3000 rpm and a centrifugation time of 20 min;

[0060] C. T...

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PUM

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Abstract

The invention which belongs to the field of traditional Chinese medicines discloses a medicine for reducing serum uric acid, a preparation method thereof and a purpose thereof. The medicine is prepared from the following medicinal materials, by weight, 5-15 parts of edible tulip bulb, 10-60 parts of Smilax glabra, 6-30 parts of parasitic loranthus, 9-45 parts of Radix Astragali, 10-30 parts of Savia miltiorrhiza, 10-60 parts of coix seed, and 9-20 parts of Gentiana macrophylla. The medicinal materials are subjected to technologies of decoction, concentration, impurity removal, drying and the like to obtain effective parts for reducing serum uric acid, and the effective parts can be prepared into different clinically acceptable dosage forms with routine methods. The purpose comprises applications in preparing medicines for reducing serum uric acid, blood fat and protecting livers and kidneys, and applications of medicines for treating hyperuricacidemia or concurrent hyperuricacidemia. The medicine of the present invention which has effects of reducing serum uric acid, blood fat and protecting livers and kidneys can be used for treating hyperuricacidemia or concurrent hyperuricacidemia.

Description

Technical field [0001] The invention is a Chinese medicine field, especially involving a drug and its preparation methods and uses that reduce blood uric acid. Background technique [0002] HyperuricAcidemia is a set of diseases caused by purine metabolism disorders or decreased uric acid excretion. Hyperuricemia in clinical asymptomatic is very common.Or joints such as joints cause pathological changes. It is the induction of gout, diabetes, coronary heart disease and other peripheral vascular diseases. The potential risk is great, which seriously affects the quality of life of patients, increases medical burden, and most clinically treats hyperuricemia.The chemical synthetic medicines have certain toxicity and side effects, and abnormal abnormalities appear again after stopping the drug.At the same time, the incidence of hyperuricemia and hypersearmia and hyperlipidemia also showed a significant upward trend. Although regulating blood lipid drugs has a good curative effect, the...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61P19/06A61P3/06
Inventor 徐红王佩
Owner CHIATAI QINGCHUNBAO PHARMA
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