N-(2-(substituted benzo- thiazole-2- amino formacyl) -phenyl group) - benzamide, as well as preparation method and usages thereof

A carbamoyl, benzothiazole technology, applied in N-(2-(substituted benzothiazole-2-carbamoyl)-phenyl)-benzamide and the fields of preparation and use thereof, can solve the inhibitory activity Weak, unstudied, etc.
CN102391207AInactive Publication Date: 2012-03-28贵州阡红农业发展有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
贵州阡红农业发展有限公司
Publication Date
2012-03-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses N-(2-(substituted benzo- thiazole -2- amino formacyl) -phenyl group) - benzamide with an effect of plant virus resistance, and a preparation method thereof. The chemical structure is expressed by a general formula (1). The invention introduces a benzothiazole ring benzoyl aminobenzene methanamide compound containing substituted benzoic acid, which adopts raw materials of substituted benzoic acid, substituted anthranllic acid, substituted benzothiazole amine, thionyl chloride and acetic oxide and is synthesized through four steps of chlorination, acidylation, cyclization and ring opening, and the compound has plant virus resisting activity and anticancer activity.
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Description

technical field

[0001] The invention relates to the synthesis and preparation method of benzothiazole ring-containing o-benzamidobenzamide compounds with anti-plant virus effect. Background technique

[0002] The o-benzamidobenzamide compounds are a class of ryanodine receptor analogs with good biological activity, and the structural modification of the ryanodine receptor as the parent has opened up a new field for the creation of new pesticides. At present, several commercialized products have appeared, such as flubendiamide and chlorantraniliprole, two broad-spectrum synthetic insecticides with ryanodine receptor structures discovered by Nippon Pesticides, Bayer and DuPont. The o-benzoylaminobenzamide compound has the same action characteristics as ryanodine, not only has excellent insecticidal activity against pests, but also is safe for mammals.

[0003] 2005 Lahm et al (Lahm, G.P.; Selby, T.P.; Freudenberger, J.H.; Stevenson, T.M.; Myers, B.J.; Seburyamo, G.; Smith, B....

Claims

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