Production process for refining glucosamine hydrochloride through membrane separation

Abstract

The invention discloses a production process for refining glucosamine hydrochloride through membrane separation. The production process comprises the following steps: based on citric acid waste residue as a raw material, hydrolyzing, performing suction filtering, and concentrating to obtain crude glucosamine hydrochloride, and refining the crude glucosamine hydrochloride through membrane separation to obtain the finished glucosamine hydrochloride, wherein a membrane is an ultrafiltration membrane, a mass transfer material is water and the driving force of mass transfer is pressure difference. The production process disclosed by the invention is simple, the product purity is high, and the glucosamine hydrochloride product produced by using the citric acid waste residue obtained through the fermentation production of citric acid as the raw material is vegetarian glucosamine hydrochloride, has no fishy smell and heavy metal pollution, is safe and environmentally friendly and meets the quality index of glucosamine hydrochloride in developed countries such as Europe and the United States.

Description

technical field [0001] The invention relates to the field of glucosamine hydrochloride, in particular to a production process for refining glucosamine hydrochloride by a membrane separation method. Background technique [0002] Citric acid is a widely used organic acid. It can be used as a sour agent, thickener, and cleaning agent. It is widely used in food, beverage, pharmaceutical, chemical, detergent and other industries. Stimulated by exports, my country's domestic citric acid production increased from 380,000 tons in 2001 to 700,000 tons in 2005, and about 800,000 tons in 2006, with an average annual increase of 12.5%. 70% of the world. At present, in the process of producing citric acid by fermentation method in most enterprises, a large amount of citric acid waste residue is not comprehensively utilized, and is directly discharged. [0003] Glucosamine Hydrochloride, English D~Glucosamine Hydrochloride, molecular formula C 6 h 13 NO 5 ·HCl, white crystal, odorless...

AI Technical Summary

Problems solved by technology

[0005] First, glucosamine hydrochloride extracted from the shell of aquatic products is not suitable for many patients with allergic reactions to aquatic products;

[0006] Second, the purification process is complicated, and the product has a fishy smell and is unstable;

[0007] Third, affected by marine environmental pollution, glucosamine hydrochloride extracted from shrimp and crab shells is inevitably polluted by heavy metals

[0008] In order to solve the defects of the above-mentioned production method, there are some records about the use of citric acid waste residue for the preparation of glucosamine hydrochloride invention patents are disclosed, such as patents such as CN200810088877.5 and CN200810238484.8, but these inventors all think that hydrochloric acid The volume concentration and hydrolysis reaction temperature should not be too high at the same time, especially the hydrolysis reaction temperature should not exceed 95°C, otherwise it will easily cause carbonization of citric acid waste residue, resulting in low yield