Normal-temperature preparation method for ultrafine lung-regulating and cough-relieving powder and special bilateral airflow sieving machine thereof
A technology of airflow sieve and powder treatment, which is used in the separation of solids from solids by airflow, chemical instruments and methods, solids separation, etc. It can solve the problem that the maximum particle size of drugs is difficult to accurately control, continuous production is impossible, and clinical dosage is small. and other problems, to achieve the effect of being suitable for large-scale industrial production, saving medicinal materials, improving cell wall breaking rate and bioavailability
Active Publication Date: 2012-06-27
北京康星健华生物科技有限责任公司
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[0004] The purpose of the present invention is to provide a method for preparing superfine powder Lifei Zhike Powder at room temperature, which effectively solves the problems of high energy consumption, difficulty in precise control of the maximum particle size of
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[0035] Such as figure 1 , 2 As shown, the normal temperature preparation method of superfine powder Lifeizhike powder of the present invention comprises the following steps:
[0036] The first step is to select the decoction pieces of raw materials lily, Ophiopogon japonicus, Qingpinellia, aster, licorice, Polygala, Anemarrhena, Adenophora, tangerine peel, Poria cocos, pumice, and dry naturally or until the moisture content is ≤10%;
[0037] The second step is to pulverize the above raw materials respectively at a temperature of 20°C to 25°C to obtain a coarse powder with a particle size of 60 to 120 mesh;
[0038] The third step, the coarse powder obtained in the second step is pressed according to Lily: Ophiopogon japonicus: Qing Pinellia: Aster: Licorice: Polygala: Anemarrhena: Adenophora: Chenpi: Poria: Pumice=9:6:5:6:3: The weight ratio of 5:5:6:5:5:4 is mixed evenly;
[0039] In the fourth step, first turn on the powder conveying fan 15, the induced draft fan 5, the ...
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Abstract
The invention discloses a normal-temperature preparation method for ultrafine lung-regulating and cough-relieving powder. The method comprises the following steps of: selecting bulk pharmaceutical decoction pieces of lily, dwarf lilyturf root, rhizoma pinelliae preparata, aster, liquoric root, thinleaf milkwort root-bark, common anemarrhena, coastal glehnia root, dried orange peel, indian buead and floatstone; smashing bulk pharmaceuticals into coarse powder at the normal temperature; uniformly mixing the obtained coarse powder according to a certain proportion, putting into a rod mill for smashing, conveying into a special bilateral airflow sieving machine through wind for sieving with a 500-mesh sieve, sieving to obtain powder of which the particle diameter is less than or equal to 25 micrometers, conveying the powder which is obtained by sieving to a cyclone aggregator through airflow generated by a draught fan for collecting to obtain finished ultrafine lung-regulating and cough-relieving powder; and collecting powder which is not sieved with the 500-mesh sieve, and conveying to the rod mill through a pipeline for smashing circularly once again. The method has the advantages that: the entire preparation process is performed at the normal temperature; the particle diameter of a prepared finished medicament is less than or equal to 25 micrometers, and the cell-wall breaking rate and the biological availability are greatly increased; and due to the adoption of the bilateral airflow sieving machine, the preparation process of the ultrafine lung-regulating and cough-relieving powder is simplified.
Description
technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a method for preparing superfine powder Lifei Zhike Powder at normal temperature; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] The main function of Lifei Zhike Powder is to moisten the lungs, resolve phlegm and relieve cough. Lifei Zhike powder currently used in livestock is mostly coarsely pulverized powder, which has problems such as large dose, coarse dosage form, poor appearance, incomplete release of active ingredients, and low bioavailability, which seriously affects the quality and therapeutic effect of traditional Chinese medicine. [0003] Traditional Chinese medicine ultrafine pulverization technology is an update and development of traditional pulverization technology. It not only retains the advantages of traditional Chinese medicine preparation technology, but also injects new vit...
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Login to view more IPC IPC(8): A61K36/8968A61K9/14A61P11/00A61P11/14A61P11/10B07B9/02
Inventor 马仲彬杨彩霞温士杰杨明峰王伟伟
Owner 北京康星健华生物科技有限责任公司
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