Polyurethane segmented copolymer containing disulfide bonds and tertiary amine groups as well as preparation method of polyurethane segmented copolymer
A technology of block copolymer and polyurethane, applied in the field of polyurethane, can solve problems such as unreported, and achieve the effect of simple and easy method, easy control and good medical application prospect.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0070] Correspondingly, the present invention provides a method for preparing the polyurethane block copolymer described in the above technical solution, which includes the following steps:
[0071] Under the action of the catalyst, the diol containing disulfide bond, the diol containing tertiary amine, and the diisocyanate are reacted in 1,2-dichloroethane for 10-60 minutes, and then polyethylene glycol monomethyl ether is added to continue the reaction 2~10h to obtain ABA type polyurethane block copolymer,
[0072] The number average molecular weight of the polyethylene glycol monomethyl ether is 500 to 10,000, preferably 1500 to 8000, more preferably 2000 to 5000; the disulfide bond-containing diol, tertiary amine-containing diol and disulfide The ratio of the total mass of isocyanate to the mass of polyethylene glycol monomethyl ether is (1-9): (1-9), preferably (3-7): (3-7), more preferably (4-6) ): (4-6); The mass ratio of the disulfide bond-containing diol to the tertiary a...
Example
[0087] Examples 1-12
[0088] Add a certain amount of PEG to a dry reaction flask, add anhydrous toluene, and azeotropically remove water at 130°C for 6 hours, then drain the remaining toluene under reduced pressure, and cool to room temperature under nitrogen protection;
[0089] Then add DHDS, HEP, catalyst dibutyl tin dilaurate and appropriate amount of 1,2-dichloroethane into the reaction flask containing PEG, and stir at 75°C until the solid is dissolved;
[0090] Then add HDI into the reaction flask, stir and react for 5 hours at 75°C under nitrogen protection;
[0091] The reaction product was settled with ether, and then the obtained solid was dissolved in chloroform, and then settled with ether, filtered with suction, and dried to obtain the product.
[0092] The formula of specific raw material monomers is shown in Table 1, and the molecular weight characteristics of the polyurethane obtained in Examples 2 to 6 are shown in Table 2.
[0093] Perform performance measurement on t...
Example
[0094] Examples 13-21
[0095] Add a certain amount of PEG with a number average molecular weight of 2000 to a dry reaction flask, add anhydrous toluene, and azeotropically remove water at 130°C for 8 hours, drain the remaining toluene under reduced pressure, and cool under nitrogen protection To room temperature;
[0096] Then add DHDS, TCI-EP, catalyst stannous octoate and an appropriate amount of 1,2-dichloroethane into the reaction flask containing PEG, and stir at 75°C until the solid is dissolved;
[0097] Then add HDI into the reaction flask, stir and react for 5 hours at 75°C under nitrogen protection;
[0098] The reaction product was settled with ether, and then the obtained solid was dissolved in chloroform, and then settled with ether, filtered with suction, and dried to obtain the product. (The specific raw material monomer formula is shown in Table 1)
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap