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Wound spray for treating bruises and preparation method of wound spray

A spray and wound technology, applied in the medical field, can solve the problems of high viscosity and surface tension of the spray stock solution, non-breathable membrane body, easy blocking of nozzles, etc., and achieves the effect of accelerating wound healing, good sterilization effect, and preventing blockage.

Active Publication Date: 2012-11-14
JIANG SU PHARMAMAXCORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This patent has the following shortcomings: the viscosity and surface tension of the spray stock solution are high, and it is not suitable for a press-type spray device; and after the volatile solvent of the liquid band-aid is fully volatilized, the liquid band-aid film is relatively dry; the film body has poor elasticity ;It is easy to block the nozzle after using the spray device; the membrane body has no air-permeable pore-causing effect

Method used

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  • Wound spray for treating bruises and preparation method of wound spray
  • Wound spray for treating bruises and preparation method of wound spray
  • Wound spray for treating bruises and preparation method of wound spray

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The components and weight percentages of the wound spray of the present embodiment are as follows:

[0045]

[0046]The preparation process is as follows:

[0047] ⑴ Pre-preparation of functional ingredients: Weigh the prescribed amount of benzalkonium chloride, rose balm, VA64, and sodium lauryl sulfate, mix evenly, add an appropriate amount of ethanol, and fully disperse in a high-speed homogeneous disperser for later use.

[0048] ⑵ Preparation of blank film-forming stock solution: Weigh the prescribed amount of PVB, isooctane, ethyl cellulose, and ethyl oleate and mix well, add the remaining amount of solvent, mix well, and dissolve them completely.

[0049] (3) The stock solution in step (1) and the blank film-forming stock solution in step (2) are fully mixed and evenly poured into a spray device to obtain a liquid band-aid containing 0.2% benzalkonium chloride.

[0050]

Embodiment 2

[0052] The components and weight percentages of the wound spray of the present embodiment are as follows:

[0053]

[0054] The preparation process is as follows:

[0055] ⑴ Pre-preparation of functional ingredients: Weigh the prescribed amount of benzalkonium bromide, jasmine oil, VA64, and sodium lauryl sulfate, mix evenly, add an appropriate amount of ethyl acetate, and fully disperse in a high-speed homogeneous disperser for later use.

[0056] ⑵ Preparation of blank film-forming stock solution: Weigh the prescribed amount of PVB, isooctane, ethyl cellulose, and ethyl oleate and mix well, add the remaining amount of solvent, mix well, and dissolve them completely.

[0057] (3) The stock solution in step (1) and the blank film-forming stock solution in step (2) are fully mixed and evenly poured into a spray device to obtain a liquid band-aid containing 0.2% benzalkonium bromide.

[0058]

Embodiment 3

[0060] The components and weight percentages of the wound spray of the present embodiment are as follows:

[0061]

[0062] The preparation process is as follows:

[0063] ⑴ Pre-preparation of functional ingredients: Weigh the prescribed amount of lecithin iodine, eucalyptus oil, VA64, and sodium lauryl sulfate, mix evenly, add an appropriate amount of acetone, and fully disperse in a high-speed homogeneous disperser for later use.

[0064] ⑵ Preparation of blank film-forming stock solution: Weigh the prescribed amount of PVB, isooctane, ethyl cellulose, and ethyl oleate and mix well, add the remaining amount of solvent, mix well, and dissolve them completely.

[0065] (3) The stock solution in step (1) and the blank film-forming stock solution in step (2) are fully mixed and evenly poured into a spray device to obtain a liquid band-aid containing 0.2% lecithin-iodine.

[0066]

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Abstract

The invention provides a wound spray for treating bruises. The wound spray is composed of effect ingredients and a blank film formation stock solution, the effect ingredient are selected from one or more of external use disinfectants, external use antibiotics, local anesthetic and skin astringing ingredients, the blank film formation stock solution comprises polyvinyl butyral, a film formation auxiliary, a plastification viscosity-regulation agent, a surface active agent, a volatilization-assisted antisticking agent, a porogen, an aromatic and a solvent. The wound spray has the advantages that the film formation auxiliary is added so that formed films are more elastic; by means of the plastification viscosity-regulation agent, the regulated viscosity of the formed films is more suitable; by means of the volatilization-assisted antisticking agent, the volatilization of the stock solution is accelerated, and a spray valve is prevented from being blocked; and by means of combined actions of the ingredients, the wound spray is good in bactericidal effects and bioadhesive performances and capable of accelerating wound healing, ventilating wounds, preventing bacteria, inhibiting the bacteria and wetting the wounds.

Description

[0001] technical field [0002] The invention relates to a wound spray which can be used for the treatment of abrasions and rapidly forms a film on the abrasions, and belongs to the field of medical technology. Background technique [0003] Skin abrasion is a very common trauma, which is caused by violent contact with the skin at a tangential position, especially the palms, elbows, knees, calves, cheeks, etc. are most likely to be injured, and the wounds vary in size. Epidermis damage can be seen after abrasions, the wound surface is pale, and there are many small bleeding spots and interstitial fluid oozing, and some wounds can go deep under the skin, resulting in full-thickness damage to the skin. If the wound surface formed after skin damage is not treated properly, it will easily lead to infection and suppuration, and it will not heal for a long time, forming scars, or local pigmentation. Therefore, how to treat the wound well and promote the early healing of the wound...

Claims

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Application Information

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IPC IPC(8): A61K45/00A61K45/06A61K47/32A61K47/38A61K47/44A61K47/20A61K9/12A61P17/02A61P31/04A61P23/02
Inventor 蒋志君曹家祥郭靖
Owner JIANG SU PHARMAMAXCORP
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