L-Se-methylselenocysteine inclusion compound and preparation method thereof

A technology of methylselenocysteine ​​and inclusion compound, applied in the field of L-selenium-methylselenocysteine ​​inclusion compound and its preparation, can solve bad smell and taste, cysteine Easy to oxidize and other problems, to achieve the effect of good embedding effect, high uniformity, simple and safe process

Active Publication Date: 2013-01-02
江西川奇药业有限公司
View PDF1 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, L-selenium-methylselenocysteine ​​is easily oxidized and has bad smell and taste, which limits its application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. After mixing 5g of mono- and diglycerin fatty acid esters and 5g of sucrose fatty acid esters, heat the mixed esters to 60°C for melting, and stir evenly to obtain the first molten material;

[0026] 2. Add 0.3 g of L-selenium-methylselenocysteine ​​to the first material, mix and stir evenly to obtain the second material;

[0027] 3. Add 8g of microcrystalline cellulose, 2g of β-cyclodextrin and 5g of maltodextrin to the second material, mix and stir evenly to obtain the third material;

[0028] 4. Cool the third material to obtain clathrate solids, crush the solids into powder with a pulverizer, and pass through a 100-mesh sieve to obtain powdered clathrate finished products.

Embodiment 2

[0030] 1. After mixing 1g of mono- and diglycerin fatty acid esters and 1g of sucrose fatty acid esters, heat the mixed esters to 70°C for melting, and stir evenly to obtain the first molten material;

[0031] 2. Add 0.01g of L-selenium-methylselenocysteine ​​to the first material, mix and stir evenly to obtain the second material;

[0032] 3. Add 1g of microcrystalline cellulose, 1g of β-cyclodextrin and 1g of maltodextrin to the second material, mix and stir evenly to obtain the third material;

[0033] 4. Cool the third material to obtain clathrate solids, crush the solids into powder with a pulverizer, and pass through a 40-mesh sieve to obtain powdered clathrate finished products.

Embodiment 3

[0035] 1. After mixing 50g of mono- and diglycerin fatty acid esters and 50g of sucrose fatty acid esters, heat the mixed esters to 100°C for melting, and stir evenly to obtain the first molten material;

[0036] 2. Add 20g of L-selenium-methylselenocysteine ​​to the first material, mix and stir evenly to obtain the second material;

[0037] 3. Add 30g of microcrystalline cellulose, 30g of β-cyclodextrin and 30g of maltodextrin to the second material, mix and stir evenly to obtain the third material;

[0038] 4. Cool the third material to obtain clathrate solids, crush the solids into powder with a pulverizer, and pass through a 200-mesh sieve to obtain powdered clathrate finished products.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
melting pointaaaaaaaaaa
Login to view more

Abstract

The invention discloses an L-Se-methylselenocysteine inclusion compound and a preparation method thereof. The L-Se-methylselenocysteine inclusion compound is prepared from the main raw materials of L-Se-methylselenocysteine, mono- and diglycerides of fatty acids and sucrose fatty acid ester as well as auxiliary materials of microcrystalline cellulose, beta-cyclodextrine and maltodextrin through certain processes. The L-Se-methylselenocysteine inclusion compound has the advantages of good inclusion effect, high uniformity, good taste-masking effect, no objectional odor after being dissolved and no influence on mouth feeling, is simple and safe in process, does not need water or organic solvent or a drying course, is time-saving and labor-saving, consumes few equipment, is simple in operation method, good in repeatability, low in equipment requirement, suitable for large-scale production and industrialization and wide in applicability, can be uniformly dispersed in milk beverage, and is not liable to moisture absorption.

Description

technical field [0001] The invention relates to an L-selenium-methylselenocysteine ​​inclusion compound and a preparation method thereof. Background technique [0002] Selenium is one of the essential trace elements for the human body. Selenium has the functions of anti-oxidation, protecting cardiovascular health, enhancing immunity, promoting growth, and anti-tumor. In addition, selenium also has detoxification effects on toxic metals. Long-term lack of selenium can lead to Keshan disease and Kaschin-Beck disease, and the phenomenon of selenium deficiency in the population is related to the low selenium content in the soil of the geographical environment in which they live and the insufficient intake of selenium in the diet. [0003] my country is a large selenium-deficient country. The low selenium content in most of the land in our country, the low selenium content in natural foods such as grains, and the differences in eating habits are the three main reasons for the ins...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/198A61K47/40A61P3/02A23L1/305
Inventor 肖小年张小平易醒李安焦爽卢艳梅章志红
Owner 江西川奇药业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap