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Application of effective site of salvianolic acids to preparation of preparations for treating skin diseases

A technology of salvianolic acid and dermatological preparations, which is applied in the application field of the effective parts of salvianolic acid in the preparation of preparations for treating dermatological diseases, and can solve the problems of easy drug resistance, large side effects and high price of antibiotics, etc. problems, to achieve the effect of easy mass production, no irritation, simple and convenient use

Inactive Publication Date: 2013-01-09
邵文远 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hormone drugs have large side effects and are prone to relapse after cure; antibiotics are prone to drug resistance; laser and other physical methods are generally expensive

Method used

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  • Application of effective site of salvianolic acids to preparation of preparations for treating skin diseases
  • Application of effective site of salvianolic acids to preparation of preparations for treating skin diseases
  • Application of effective site of salvianolic acids to preparation of preparations for treating skin diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Prepare solution.

[0026] Use 75 grams of the solid powder of the effective part of Salvia miltiorrhiza (prepared in Example 6), mix it with 50 ml of distilled water, and dilute to 100 ml with water to make an aqueous solution, centrifuge to remove the precipitate, and the supernatant can be used as a solution for treating skin diseases Agent. Apply it to the surface of skin warts and herpes, three times a day, the dosage is 0.4 and 0.8 ml each time. After 35 days and 25 days of treatment, their skin warts and herpes have almost reached or nearly disappeared ( Figure 1-2 ).

Embodiment 2

[0028] Prepare solution.

[0029] Use 75 grams of salvia polyphenolic acid active part powder (prepared in Example 6), mix with 50 ml of 20% ethanol aqueous solution, and then dilute to 100 ml with 20% ethanol aqueous solution to make ethanol aqueous solution, centrifuge to remove the precipitate, and supernatant It can be used as a solution. Apply it on the acne face, apply 2.5ml three times a day, after 17 days of continuous use, the acne is almost gone ( image 3 ).

Embodiment 3

[0031] Preparation of solution for the treatment of skin burn wounds.

[0032] Use 75 grams of salvia polyphenolic acid effective part powder (prepared in Example 7), mix with 50 ml of distilled water, and then dilute with water to 100 ml to make an aqueous solution, centrifuge to remove the precipitate, the supernatant can be used as a solution, smear On the surface of the burn wound, a thin film of the effective part of salvianolic acid is formed, which can isolate the invasion of new bacteria and viruses, and at the same time kill the infected bacteria and viruses, and also invigorate blood and remove stasis, resist oxidation, and inhibit platelets. Aggregate, and inhibit thrombosis, and promote wound healing. Apply 0.8ml three times a day, after 20 days of treatment, the burn wound is healed ( Figure 4 ).

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PUM

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Abstract

The invention provides application of an effective site of salvianolic acids to preparation of preparations for treating skin diseases in vitro. The preparations are solution agents, ointment or cream which is prepared from the effective site, which serves as an active ingredient, of the salvianolic acids and pharmaceutic adjuvants; and the content of the effective site of the salvianolic acids in the preparations is 10 to 75 percent. According to different skin diseases, the preparations can be used for treating viral skin diseases such as wart or herpes, bacterial skin diseases such as inflammations and tinea, dermatoma or burn wounds, so that the skin diseases are cured or improved obviously. The preparations are clear in active ingredients, high in content, high in efficiency, safe, non-toxic, convenient to use, low in cost and easy to produce on a large scale, are suitable for various people and have high application value, and sequelae are avoided.

Description

Technical field [0001] The invention relates to traditional Chinese medicine, in particular to the application of the effective part of salvia miltiorrhiza polyphenolic acid in preparing preparations for treating skin diseases. Background technique [0002] Skin disease is a common disease that affects people's health and appearance, frequently-occurring and recurring. At present, when treating more than 2000 kinds of skin diseases externally, most of them are treated with hormone drugs or antibiotic drugs, or physical methods such as laser. Hormonal drugs have large side effects and are easy to relapse after cure; antibiotics are prone to drug resistance; physical methods such as laser treatment are generally expensive. There are also some skin diseases that cannot be cured for a long time, affecting people's physical and mental health and physical appearance for a long time, and some even cause cancer. Therefore, finding effective, safe, non-toxic, inexpensive and easy-to-use...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K31/343A61P17/00A61P17/02A61P31/04A61P31/12A61P35/00
Inventor 邵文远姜雪成邵明川
Owner 邵文远
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