Drug composition suitable for transdermal drug delivery and containing granisetron as well as preparation and application of same
A technology of granisetron and composition, which is applied in the pharmaceutical composition containing granisetron suitable for transdermal administration and its preparation and application field, to achieve the improvement of cohesive strength and adhesive performance, small skin irritation, The effect of adequate bond strength
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0034] Example 1
[0035] In a suitable container, weigh in 1.47 grams RS100 (manufactured by Evonik Degussa, Germany), add appropriate amount of ethyl acetate (Beijing Yili Fine Chemicals Co., Ltd., chemically pure) to soak for 2-3 hours to completely dissolve it, and then weigh in 24.42 grams of 30% solid content Polyacrylate pressure-sensitive adhesive (see: Yang Yukun, "Technical Handbook of Pressure-Sensitive Adhesive Products", Chemical Industry Press, September 2004, pages 260-261 for the preparation method). The monomers used and their contents are: Acrylamide 3.8%, butyl acrylate 33.1%, 2-ethylhexyl acrylate 40.9%, vinyl acetate 21%, and α-methacrylic acid 1.2%. The above monomers were purchased from Beijing Yili Fine Chemicals Co., Ltd., chemically pure), and then 0.55 g of granisetron (Sinopharm Group Chuankang Pharmaceutical Co., Ltd.) and 1.04 g of isopropyl myristate (Kunshan City, Jiangsu Province) were added. Produced by Huaxin Daily Chemicals Co., Ltd.), add a...
Example Embodiment
[0036] Example 2
[0037] Using the method of Example 1, according to the weight percentage of each component in the matrix layer given in Table 1, the patch of Example 2 was prepared.
Example Embodiment
[0038] Example 3-6
[0039] Using the method of Example 1, according to the weight percentage of each component in the matrix layer given in Table 2, the patches of Examples 3-6 were prepared.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap