Fifteen-component alplily eyesight improving tablet and preparation process thereof

A technology of eye tablet and myrobalan, which is applied to Shishiwei Luodi Mingmu tablet and its preparation process, Chinese and Tibetan medicinal preparations and the field of preparation thereof, can solve the problem of uncontrollable preparation quality, uneven distribution of medicinal taste, and no controllable quality. Standard and other problems, to achieve the effect of fast drug effect, uniform distribution of flavor and easy disintegration

Inactive Publication Date: 2013-02-13
青海普兰特药业有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Since Shiwuweiluodi Mingmu Pill is a classic Tibetan medicine, it has the following disadvantages: (1) Shuifan Pill disintegrates slowly or does not disintegrate, which affects the efficacy of the medicine; (2) The flavor of each medicine in the pill is unevenly distributed; ( 3) Without controllable quality standards, the quality of preparations cannot be controlled

Method used

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  • Fifteen-component alplily eyesight improving tablet and preparation process thereof
  • Fifteen-component alplily eyesight improving tablet and preparation process thereof

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preparation example Construction

[0039] Preparation of reference solution Accurately weigh 0.7mg of ferulic acid reference substance, put it in a 10ml measuring bottle, add an appropriate amount of methanol, shake it in a water bath to dissolve, place it at room temperature, dilute it to the mark, shake it well, and you can get it (every 1ml contains ferulic acid ferulic acid 70μg).

[0040] Preparation of the test solution Take 5g of this product, grind it finely, weigh it accurately, put it in a stoppered Erlenmeyer flask, add 100ml of water precisely, weigh it, shake it well, treat it with ultrasonic for 30 minutes, weigh it again, make up the lost weight with water, filter, Accurately measure 25ml of the subsequent filtrate, adjust the pH to 2 with hydrochloric acid, shake and extract with diethyl ether 4 times, 15ml each time, combine the diethyl ether solution, evaporate to dryness, add 2ml of methanol to the residue, weigh it, heat slightly to dissolve, let it cool Finally, weigh the weight again,...

Embodiment

[0056] 1. Determination of the basic process

[0057] 2. [Preparation method] The above fifteen herbs are crushed into fine powder, sieved, mixed evenly, added appropriate amount of excipients, granulated, dried, pressed into tablets, and made into 1000 tablets, ready to be obtained.

[0058] 3. Process flow chart see figure 1

[0059] 4. Research on process rationality

[0060] 4.1 Choice of dosage form

[0061] Shiwuwei Luodi Mingmu Pills is a traditional classic Tibetan medicine Shuipan pill preparation, which has the effect of clearing the liver and improving eyesight. It is mostly used for the treatment of early cataracts in senile diseases, dry eyes, tearing, conjunctivitis and other eye diseases. Because there are few kinds of drugs for the treatment of such diseases, Shiwuweiluodi Mingmu Pills are widely used by middle-aged and elderly patients because of their rapid effect, clear and stable curative effect. However, this dosage form has disadvantages su...

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PUM

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Abstract

The invention discloses a fifteen-component alplily eyesight improving tablet. The tablet is characterized by comprising the following fifteen Chinese and Tibetan medicinal materials: alplily, gypsum rubrum, caraway, travertine, liquorice, safflower, Zhaxun extract, clove, little multibanded krait, meconopsis, scrap iron (medicine terminalia fruit prepared), medicine terminalia fruit, denucleated emblic leafflower fruit, hematite haematitum and belleric terminalia fruit. The fifteen-component alplily eyesight improving tablet has the functions of removing liver heat and improving eyesight and is used for treating early cataract and conjunctivitis. Compared with water-bindered pills, the tablet has the advantages of (1) short growing period, (2) measurement accuracy, (3) easy disintegration and quick drug action, (4) uniform distribution of each drug in the tablet, and (5) convenient administration and portability. The fifteen-component alplily eyesight improving tablet is a compound starch tablet, is higher than the standard of pills in disintegration speed, weight difference and hygienic indexes, and the indexes can fulfill requirements in tests and stability tests according to the quality standard of the novel medicine.

Description

[0001] technical field [0002] The invention belongs to the technical field of medicine, and relates to a traditional Chinese and Tibetan medicine preparation and a preparation process thereof, in particular to Shiwuwei Luodi Mingmu Tablets and a preparation process thereof. Background technique [0003] Early cataract and conjunctivitis are multiple and common diseases in my country. Cataracts, in particular, have a particularly high incidence among middle-aged and elderly people. The classic Tibetan medicinal preparation Shiwuwei Luodi Mingmu Pills has a remarkable curative effect on early cataract and conjunctivitis. Due to the inherent shortcoming of water flooding pill, influence market sales. [0004] Since Shiwuweiluodi Mingmu Pill is a classic Tibetan medicine, it has the following disadvantages: (1) Shuifan Pill disintegrates slowly or does not disintegrate, which affects the efficacy of the medicine; (2) The flavor of each medicine in the pill is unevenly distri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896G01N30/02G01N30/90A61P27/02A61P27/12A61K33/06A61K33/08A61K33/26A61K35/58A61K35/583
Inventor 代冬海王世静潘建国余梅祝清灿张医名李生萍刘蓓蓓李堂福
Owner 青海普兰特药业有限公司
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