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Pollen pini water extract enteric-coated tablet for preventing alcoholic fatty liver (AFL)

An alcoholic fatty liver, water extract technology, applied in the field of plants, can solve problems such as difficulty in functioning, obstacles to transport, and increased choline requirements

Active Publication Date: 2014-08-13
YANTAI NEW ERA HEALTH IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

② Alcohol specifically increases the choline requirement, and the deficiency of phospholipids affects the synthesis of lipoproteins, thus hindering the export of
When people drink a lot of alcohol, they also ingest a lot of food, especially high-oil and high-fat food, which makes the stomach full, and it usually takes about 2 hours to empty the stomach content. Drugs for fatty liver, because the dosage is too different from the contents of the stomach, it is difficult to work and become ineffective. However, if a large dose of anti-alcohol drugs is used, it will be limited by the stomach capacity and cannot be implemented, so it is used after meals Anti-alcoholic drugs must be processed in a gastric insoluble manner, which is the main reason why we develop enteric-coated tablets

Method used

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  • Pollen pini water extract enteric-coated tablet for preventing alcoholic fatty liver (AFL)
  • Pollen pini water extract enteric-coated tablet for preventing alcoholic fatty liver (AFL)
  • Pollen pini water extract enteric-coated tablet for preventing alcoholic fatty liver (AFL)

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Experimental program
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Embodiment Construction

[0030] One, prepare the lyophilized powder of the water extract of pine pollen preventing and treating alcoholic fatty liver:

[0031] 1. Pine pollen is removed and dried to reduce the water content to 4-8%.

[0032] 2. The pine pollen is broken by means of airflow crushing and wall breaking.

[0033] 3. Soak the broken pine pollen in pure water at normal pressure and temperature, and at the same time treat it with low-frequency ultrasonic waves for 10-40 minutes, and control the temperature of the ultrasonic extraction solution at 10-40°C.

[0034] 4. Remove solid impurities by refrigerated centrifugation at 8,000 to 15,000 rpm, and take the supernatant.

[0035] 5. The supernatant is separated by ultrafiltration with a 5000D molecular sieve at an ambient temperature of 1-5° C. to obtain water-soluble substances of pine pollen with a molecular weight below 5000.

[0036] 6. Freeze-drying the above-mentioned pine pollen aqueous extract for 24-48 hours to prepare a freeze-dri...

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Abstract

The invention provides a pollen pini water extract enteric-coated tablet for preventing alcoholic fatty liver (AFL), relating to the technical field of processes for preparing enteric-coated tablets from plants, especially pollen pini water extracts. The enteric-coated tablet is formed by lyophilized powder of the pollen pini water extract which is obtained by a pollen pini water extraction method and has molecular weight less than 5000, bitter gourd powder, cassia seed powder, palatinitol, magnesium stearate and enteric-coated coating powder. The enteric-coated tablet has obvious effect of preventing AFL, does not have side effect, is low in cost and is simple and practicable.

Description

technical field [0001] The invention relates to the technical field of preparing enteric-coated tablets from plants, especially from pine pollen water extract. Background technique [0002] According to WHO statistics, there are nearly 200 million long-term drinkers in my country, and liver damage is caused by the toxic effects of alcohol. About 2 / 3 of alcoholics can develop alcoholic liver disease (ALD), which includes alcoholic liver damage, fatty liver ( AFL), hepatitis, liver fibrosis and liver cirrhosis are sequential and gradual processes, and the pathogenesis is relatively complicated. The therapeutic effect of traditional Chinese medicine on AFL is acceptable. Alcoholic liver disease is one of the common clinical liver diseases, mainly caused by long-term heavy drinking of liver damage. According to Western studies, alcoholic liver disease is the main cause of liver cirrhosis, and almost 50% of patients with liver cirrhosis have the habit of long-term drinking. [0...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/482A61K36/15A61K9/28A61P1/16
Inventor 王桐周斌刘志河石丽花叶满红徐宏楠于建伟鞠东李明
Owner YANTAI NEW ERA HEALTH IND