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Traditional Chinese medicine composition for treating dysentery and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating dysentery and its preparation, can solve problems such as intestinal flora disorder, affecting poultry and livestock egg production and calving, affecting the safety of poultry meat and egg products, etc., achieving Less toxic side effects, less drug resistance, strong antibacterial effect

Active Publication Date: 2014-06-04
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug residues of feeding antibiotics are relatively heavy. Studies have shown that the drug residues of antibiotics eaten by animals and poultry cannot be excreted, which can easily cause intestinal flora disorder and affect poultry and livestock egg production. Especially in the season of dysentery, some breeders In order to avoid a large number of dysentery infections, antibiotics are mixed in the feed for dozens of days or even months, and the consequences will directly and seriously affect the safety of human consumption of poultry meat and eggs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Prescription: Dijincao 200g, oregano 200g, agrimony 150g, white grass 120g, purslane 120g.

[0019] Preparation method: Take 200g of oregano, add 1600g of 8 times the amount of water, then add 30g of sodium chloride with 15% of the weight of oregano, distill and extract for 4 hours, receive the volatile oil, then add 60g of β-cyclodextrin with 5 times the weight of the volatile oil and 180g of water 15 times the amount of oregano, grind for 2 hours with a colloid mill, dry at low temperature, and pulverize;

[0020] Take 200g of Dijincao, 150g of Agrimony, 120g of Vernaceae, 120g of Purslane, add 7080g of 12 times the amount of water, heat and extract twice, each time for 1.5 hours, filter, and the filtrate is concentrated under reduced pressure to the relative density at 60°C It is a thick paste of 1.30~1.35, dried under reduced pressure, crushed; then take the above two kinds of fine powder, mix them in equal amounts to make a mixed fine powder, take 1 part of mixed f...

Embodiment 2

[0022] Prescription: Dijincao 2500g oregano 2500g agrimony 1200g white grass 900g purslane 900g

[0023] Preparation method: take oregano, add 6 times the amount of water 15kg, add 1.5kg of sodium chloride with 10% water weight, distill and extract for 4 hours, receive volatile oil, add 650g of β-cyclodextrin with 4 times the weight of volatile oil and 15 times the amount Grind 1950g of water with a colloid mill for 2 hours, dry at low temperature, and pulverize; take Dijincao, Agrimony, Vernaceae, and Purslane, add 14 times the amount of medicinal materials and 77kg of water, heat and extract 3 times, 1.5 hours each time, Filtrate, concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30 to 1.35 at 60°C, dry under reduced pressure, and pulverize; take the above two fine powders and mix them evenly to obtain a powder. (Powder finished product rate 97.6%, quercetin transfer rate 64.8%)

Embodiment 3

[0025] Prescription: Dijincao 15kg oregano 15kg Agrimony 15kg Turnbaca 12kg Purslane 15kg

[0026] Preparation method: take oregano, add 150kg of water, add 30kg of sodium chloride, distill and extract, receive 2 times the amount of distillate, and set aside; take Dijincao, agrimony, vermicelli, and purslane, add 456kg of water, heat and extract 2 Once, each time for 1.5 hours, filter, the filtrate is concentrated under reduced pressure to 60 ° C, the relative density is 1.05 ~ 1.10, add oregano distillate, mix well, filter, add an appropriate amount of sodium benzoate to make a mixture, fill it, and get . (The finished product rate of the mixture is 96.5%, and the transfer rate of quercetin is 62.4%)

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Abstract

The invention discloses a composition of five Chinese medicinal herbs with relieving the dysentery, and a preparation method thereof, belonging to the field of livestock and poultry pharmaceuticals technology. The pharmaceutical composition is prepared by extracting the active ingredients from crude drugs of humifuse euphorbia herb, oregano, agrimonia pilosa ledeb, potentilla discolor bunge, portulacae herba and the like by adopting modes of acid water extraction, steam distillation and the like according to different properties of drugs, and is prepared into powder, granules or mixture. The pharmaceutical composition has the efficacies of clearing heat and detoxifying and stopping dysentery, and is mainly used for treating dysentery infected by the livestock and poultry.

Description

technical field [0001] The invention belongs to the technical field of livestock and poultry medicines, and in particular relates to a traditional Chinese medicine composition for treating dysentery and a preparation method thereof. Background technique [0002] Dysentery is a disease characterized by dysentery and abdominal pain caused by damp-heat toxins and pathogenic stagnation in the colonic tract, frequent straining, unsmooth diarrhea, red and white pus and blood in the dysentery, and is an animal disease that occurs mainly in spring and autumn. my country is a big country that raises livestock and poultry. The incidence of dysentery in these animals is extremely high every year, especially in the breeding base, which is highly contagious. If it is not treated in time, it can lead to a large number of deaths. At present, the usual practice of the breeding industry for the treatment of dysentery is to directly feed various western medicine antibiotics when the dysentery...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61P1/12A61P31/04
Inventor 秦志华单虎杨海燕张启迪张倩
Owner QINGDAO AGRI UNIV