Traditional Chinese cataplasm for traumatic injury as well as preparation method thereof

A technique for cataplasm and bruises, applied in the direction of pharmaceutical formulations, non-central analgesics, medical preparations containing active ingredients, etc., can solve the problem of rubber ointment prone to pain, skin irritation and allergies, inapplicable Open damage and other problems, to achieve the effect of improving compatibility and affinity, reducing irritation and sensitization, and high production safety factor

Active Publication Date: 2013-05-08
GUIZHOU JINQIAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern pharmacological studies have proved that Compound Shangfuning Ointment has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and has definite curative effect on limb pain caused by various traumatic injuries. The existing method of producing Compound Shangfuning Ointment generally uses pharmaceutical The method on the standard (WS-10989 (ZD-0989)-2002), the preparation recorded in the above standard is a rubber plaster, the rubber plaster made by the above method is ...

Method used

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  • Traditional Chinese cataplasm for traumatic injury as well as preparation method thereof
  • Traditional Chinese cataplasm for traumatic injury as well as preparation method thereof
  • Traditional Chinese cataplasm for traumatic injury as well as preparation method thereof

Examples

Experimental program
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Embodiment 1

[0142]Prescription: Touguxiang 737g, Red Hemp 737g, Feilongzhangxue 592g, Auspicious Grass 737g, Sorrelwort 592g, White Dragon Beard 444g, Polygonum cuspidatum 737g, Panax notoginseng 737g, Camphor 96g, Borneol 163g, Menthol 126g, Glycerin 7600g, sodium polyacrylate 1200g, sodium carboxymethylcellulose 400g, gelatin 600g, sodium carbonate 100g, lidocaine 335g and purified water 6000g.

[0143] Process:

[0144] ① Grind Touguxiang, Honghema, Feilongzhangxue, Auspicious Grass, Sorrelwort, White Dragon’s Beard, Polygonum cuspidatum and Panax notoginseng into coarse powder, extract twice with 90% ethanol for 1.5 hours each time, filter, Ethanol is recovered from the filtrate under reduced pressure and concentrated to an extract with a relative density of 1.28 at 40°C;

[0145] ② Crush borneol, menthol, and camphor and mix with a small amount of ethanol, and stir well;

[0146] ③ Mix the solution of step ② with the extract of step ①;

[0147] ④ Pour the sodium carbonate and lido...

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Abstract

The invention discloses a traditional Chinese cataplasm for traumatic injury. The traditional Chinese cataplasm for traumatic injury is prepared from radix gaultheriae, largespike woodnettle root, asiatic toddalia root, Pink Reineckea Herb, Oxalis corniculata L, Chinese Alangium, Polygonum cuspidatum, pseudo-ginseng, camphor, borneol, menthol, glycerol, sodium polyacrylate, sodium carboxymethylcellulose, gelatin, sodium carbonate, lidocaine and purified water. According to the cataplasm refined by Chinese herb extracts based on water soluble high-molecular compounds as a matrix, the compatibility and affinity of medicine and skin are improved and transdermal absorption is enhanced; in addition, the drug loading capacity is large, the bioavailability is high, the moisturizing period is long and the sweat-resistance is strong. The cataplasm can be uncovered and pasted repeatedly, is small in irritation, and does not cause skin allergy.

Description

technical field [0001] The invention relates to a traditional Chinese medicine catarrh ointment for bruises and a preparation method thereof, belonging to the field of pharmaceutical technology. Background technique [0002] The rapid development of today's science and technology supports the high-speed operation of all walks of life in society, and it also shows the important position of science and technology in the field of pharmaceutical preparations. Various unprecedented new drug dosage forms have come out one by one, bringing many benefits to patients in various treatments; but At present, many drugs are mainly administered orally, and most drugs undergo the first-pass effect in the liver or degrade in the gastrointestinal tract after oral administration, which reduces the efficacy of the drug; however, a drug-based active ingredient mixed with a suitable matrix After uniformity, the plaster made by coating on the backing material, that is, a kind of external plaster,...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/70A61P29/00A61K31/125A61K31/045A61K31/167
Inventor 张芝庭张涛涛
Owner GUIZHOU JINQIAO PHARMA
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