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Novel copper bactericide and synthetic method thereof

A synthesis method and fungicide technology, applied in the field of new copper fungicides and their synthesis, can solve the problems of human health and harmful biological growth, and achieve the effect of environmental friendliness and good antibacterial effect

Inactive Publication Date: 2013-08-14
QIQIHAR UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims at overcoming the problem that the existing bactericide aluminum triethylphosphonate in the background technology is harmful to human health and biological growth, and provides a novel copper bactericide and a synthesis method thereof. The bacteriostatic effect of the copper bactericide is Well, at the same time, copper diethylphosphonate is friendly to the environment, copper is one of the 18 trace elements in the human body, and it is harmless to the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Mix the 1:4 chloroform and absolute ethanol, pour it into a 100 mL three-necked flask, and then use the dropping funnel to drop the mixed solution of chloroform and phosphorus trichloride with a volume ratio of 5:4. mL, use ice water to control the temperature at 6~8 ℃, start the stirrer, and dropwise addition is completed in about 1 h. Hydrogen chloride gas generated during the reaction was absorbed with 5% sodium hydroxide solution. After the reaction is complete, pour the reactant into a beaker, neutralize to pH=7~8 with 10% sodium carbonate solution, add deionized water to wash three times, separate with a separatory funnel, and distill under reduced pressure to obtain sub Diethyl Phosphate (C 2 h 5 OPHO C 2 h 5 ), the yield was 94.8%.

[0018] Add diethyl phosphite into a 250 mL iodine flask, add equimolar 10% ammonia water, and carry out ammoniation reaction in a water bath at 40 °C for 48 h to obtain ammoniated product C 2 h 5 OPHOONH 4 . Transfer the am...

Embodiment 2

[0020] Mix the 1:4 chloroform and absolute ethanol, pour it into a 100 mL three-necked flask, and then use the dropping funnel to drop the mixed solution of chloroform and phosphorus trichloride with a volume ratio of 5:4. mL, use ice water to control the temperature at 6~8 ℃, start the stirrer, and dropwise addition is completed in about 1 h. Hydrogen chloride gas generated during the reaction was absorbed with 5% sodium hydroxide solution. After the reaction is complete, pour the reactant into a beaker, neutralize to pH=7~8 with 10% sodium carbonate solution, add deionized water to wash three times, separate with a separatory funnel, and distill under reduced pressure to obtain sub Diethyl Phosphate (C 2 h 5 OPHO C 2 h 5 ), the yield was 94.8%.

[0021] Add diethyl phosphite into a 250 mL iodine flask, add equimolar 10% ammonia water, and carry out ammoniation reaction in a water bath at 40 °C for 48 h to obtain ammoniated product C 2 h 5 OPHOONH 4 . Transfer the am...

Embodiment 3

[0023] Mix 1:4 chloroform and absolute ethanol, pour it into a 100 mL three-necked flask, and then use a dropping funnel to drop the mixed solution of chloroform and phosphorus trichloride with a volume ratio of 5:4. mL, use ice water to control the temperature at 6~8 ℃, start the stirrer, and dropwise addition is completed in about 1 h. Hydrogen chloride gas generated during the reaction was absorbed with 5% sodium hydroxide solution. After the reaction is complete, the reactant is poured into a beaker, neutralized to pH=7~8 with 10% sodium carbonate solution, then washed with deionized water three times, separated with a separatory funnel, and then distilled under reduced pressure to obtain sub Diethyl Phosphate (C 2 h 5 OPHO C 2 h 5 ), the yield was 94.8%.

[0024] Add diethyl phosphite into a 250 mL iodine flask, add equimolar 10% ammonia water, and carry out ammoniation reaction in a water bath at 40 °C for 48 h to obtain ammoniated product C 2 h 5 OPHOONH 4 . Tr...

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PUM

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Abstract

The invention relates to a novel copper bactericide and a synthetic method thereof, which mainly aims at solving the problem that the existing bactericide fosetyl-aluminium is harmful to human health and biological growth. The novel copper bactericide has a chemical name copper diethyl phosphonate and is shown by the following molecular formula: [C2H5OPHOO] 2Cu. The synthetic method comprises the following steps of firstly carrying out esterification reaction on phosphorus trichloride and alcohol, after ammonolysis reaction of the obtained diethyl phosphite and ammonia water, adding copper sulfate for metathetical reaction so as to prepare the diethyl phosphonic acid copper product. The copper bactericide has good antibacterial effect, and furthermore, the diethyl phosphonic acid copper has environment-friendly property.

Description

technical field [0001] The invention relates to the field of pesticide preparation, in particular to a novel copper fungicide and a synthesis method thereof. Background technique [0002] At present, aluminum triethylphosphonate (abbreviated as aluminum ethylphosphonate), a fungicide widely used in the production of vegetables and fruits, is an organophosphate successfully developed by Rhone-Poulenc Co. in France in 1978. Fungicide, it is mainly used to prevent downy mildew of cucumber, Chinese cabbage, cabbage and other vegetables. Because triethylphosphonate aluminum has systemic properties, a large amount of aluminum ions remain in vegetables and fruits. Only 10%-15% can be excreted out of the body, and most of it will accumulate in the body, which will not only damage the brain, but also cause visual and motor coordination failure, especially for the elderly and children. At the same time, aluminum will also affect the acidity of the soil, causing greater damage to plan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07F9/142A01P3/00A01N57/12
Inventor 唐万侠朱吕会赵明鹏磊魏金刚
Owner QIQIHAR UNIVERSITY