Medical liquid dressing and preparation method thereof
A liquid dressing and solid technology, applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of patients' ideological and economic burden, increase patient's pain, and troublesome wound care, and achieve the promotion of wound healing, good treatment effect, and clinical relief. The effect of resistance
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Embodiment 1
[0017] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first add chitosan quaternary ammonium salt (produced by Jiaxing Kerui Biotechnology Co., Ltd.) 87.5g and stir to make it Complete dissolution takes about 2-3 hours. After completion, slowly add 5% organic silicon quaternary ammonium salt (produced by Jiaxing Kerui Biotechnology Co., Ltd.) solution 5250ml and 20% chlorhexidine gluconate solution 437.5ml, stir for about 30 minutes while adding, and then carry out Thoroughly stir for about 1-2 hours to obtain a mixed solution. Put it in a container by filtration, remove all air bubbles overnight, and it is a semi-finished product. The next day, the solid content is 0.22%, and the pH value is 4.8.
Embodiment 2
[0019] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first add 138.3g of chitosan quaternary ammonium salt and stir to completely dissolve it, the process takes about 2-3 hours. After finishing, slowly add 5250ml of 5% organosilicon quaternary ammonium salt solution and 437.5ml of 20% chlorhexidine gluconate solution, stir for about 30 minutes while adding, then fully stir for about 1-2 hours, to obtain mixture. Put it in a container by filtration, remove all air bubbles overnight, and it is a semi-finished product. The next day, the solid content is 0.47%, and the pH value is 4.3.
Embodiment 3
[0021] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first put 52.7g of chitosan quaternary ammonium salt into the mixing tank, and then stir to dissolve it completely, the process is about It takes 2-3 hours. After finishing, slowly add 5250ml of 5% organosilicon quaternary ammonium salt solution and 437.5ml of 20% chlorhexidine gluconate solution, stir for about 30 minutes while adding, then fully stir for about 1-2 hours, to obtain mixture. Put it in a container by filtration, remove all air bubbles overnight, it is a semi-finished product, measure the solid content of 0.13% the next day, and the pH value is 5.2, divide the bottles into bottles, and conduct a sterility test, and it is a finished product after passing the test.
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