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Medical liquid dressing and preparation method thereof

A liquid dressing and solid technology, applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of patients' ideological and economic burden, increase patient's pain, and troublesome wound care, and achieve the promotion of wound healing, good treatment effect, and clinical relief. The effect of resistance

Active Publication Date: 2013-09-18
海南一鸿实业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, it is difficult for traditional medical dressings to apply to these parts, and it is quite inconvenient to use, and the care of the wound surface is very troublesome.
[0005] The above factors are likely to increase the suffering of patients and prolong the length of hospital stay, bringing a double burden of thought and economy to patients.

Method used

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  • Medical liquid dressing and preparation method thereof
  • Medical liquid dressing and preparation method thereof
  • Medical liquid dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first add chitosan quaternary ammonium salt (produced by Jiaxing Kerui Biotechnology Co., Ltd.) 87.5g and stir to make it Complete dissolution takes about 2-3 hours. After completion, slowly add 5% organic silicon quaternary ammonium salt (produced by Jiaxing Kerui Biotechnology Co., Ltd.) solution 5250ml and 20% chlorhexidine gluconate solution 437.5ml, stir for about 30 minutes while adding, and then carry out Thoroughly stir for about 1-2 hours to obtain a mixed solution. Put it in a container by filtration, remove all air bubbles overnight, and it is a semi-finished product. The next day, the solid content is 0.22%, and the pH value is 4.8.

Embodiment 2

[0019] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first add 138.3g of chitosan quaternary ammonium salt and stir to completely dissolve it, the process takes about 2-3 hours. After finishing, slowly add 5250ml of 5% organosilicon quaternary ammonium salt solution and 437.5ml of 20% chlorhexidine gluconate solution, stir for about 30 minutes while adding, then fully stir for about 1-2 hours, to obtain mixture. Put it in a container by filtration, remove all air bubbles overnight, and it is a semi-finished product. The next day, the solid content is 0.47%, and the pH value is 4.3.

Embodiment 3

[0021] Pour 170,000ml of pure water into the mixing tank, set the stirring speed of the mixer to 30-35 rpm and stir, first put 52.7g of chitosan quaternary ammonium salt into the mixing tank, and then stir to dissolve it completely, the process is about It takes 2-3 hours. After finishing, slowly add 5250ml of 5% organosilicon quaternary ammonium salt solution and 437.5ml of 20% chlorhexidine gluconate solution, stir for about 30 minutes while adding, then fully stir for about 1-2 hours, to obtain mixture. Put it in a container by filtration, remove all air bubbles overnight, it is a semi-finished product, measure the solid content of 0.13% the next day, and the pH value is 5.2, divide the bottles into bottles, and conduct a sterility test, and it is a finished product after passing the test.

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PUM

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Abstract

The invention discloses medical liquid dressing and a preparation method thereof, and aims at providing the medical liquid dressing which has long-acting antibacterial effects, the capability of reducing formed scars and has a good treatment effect on wound healing. The medical liquid dressing is characterized by containing 0.02-1% of solid ingredients and the balance of water; the solid ingredients include 10-80% of chitosan quaternary ammonium salt, 20-90% of organosilicon quaternary ammonium salt, and 6-30% of auxiliary materials. The preparation method comprises the steps of adding water to an agitating tank, setting the agitating speed of the agitator to 30-35 r / min; firstly, adding chitosan quaternary ammonium salt to agitate and completely dissolve for about 2-3 hours; adding an organosilicon quaternary ammonium salt solution and a chlorhexidine gluconate solution when agitating, fully agitating for 1-2 hours to obtain a mixing solution; filtering the mixing solution in a container; removing air bubbles over a night; determining a semi-finished product of which the solid content is 0.02-1% and the PH value is 4.1-7.5 in the next day; and sub-charging in bottles to form the finished product after a sterile test is qualified. The medical liquid dressing belongs to the technical field of preparation of medicaments.

Description

technical field [0001] The invention discloses a dressing and a preparation method thereof, in particular to a medical liquid dressing and a preparation method thereof, belonging to the technical field of medicine preparation. Background technique [0002] Wound healing is a complex process, which is affected by many factors, such as infection, wound pollution, autoimmunity, etc. Among them, infection is the most common factor, and infection is the main reason affecting wound healing. Therefore, it is very necessary to create a good environment for wound healing and prevent wound infection. Currently, local external application of "antibacterial drugs" and "dressings" are used for clinical treatment. "Antibacterial drugs" lead to more and more serious clinical drug resistance problems and "dressings" have no clear antibacterial effect, which makes wounds prone to infection, slow healing and scar formation. [0003] Traditional medicine clinically treats various skin injurie...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/20A61L15/42
Inventor 王珍
Owner 海南一鸿实业发展有限公司
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