Anti-allergic rhinitis combination drug

An anti-allergic and drug-based technology, applied in drug combinations, allergic diseases, medical formulas, etc., can solve the problems of incurability, poor treatment effect, high cost, etc., and achieve the disappearance of runny nose symptoms, not easy to relapse, and short course of treatment Effect

Inactive Publication Date: 2013-09-25
武文栋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many ways to treat allergic rhinitis on the market at present, such as anti-inflammatory treatment: antihistamine drugs, local hormones, this method can only relieve symptoms (similar to antipyretic drugs during fever), and the drugs have certain side effects; specific immunotherapy ( Desensitization): This method needs more than 2 years, the cost is very high, and it is only effective for a single sensitizer; there are many related therapeutic drugs, such as loratadine is used to relieve the relevant symptoms of allergic rhinitis. The treatment of allergic rhinitis is dependent. Generally, the condition can be controlled for more than an hour, and then relapses still occur; there is also Miao medicine Bikeling spray, which can quickly relieve the symptoms (generally effective in 5 minutes), but about 0.5 minutes after stopping the drug. hr still relapses; there are also various methods such as acupuncture, laser (burning the inner surface of the nasal cavity to promote scab formation, the patient is very painful during the treatment process, and it is effective in a short period of time after treatment, but the recurrence rate is extremely high), oral administration, etc. Most of the treatments The effect is not good, although some medicines have a certain effect but cannot cure the disease

Method used

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  • Anti-allergic rhinitis combination drug
  • Anti-allergic rhinitis combination drug
  • Anti-allergic rhinitis combination drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 (medicine combination): vitamin B6 sheet (2 * specification 10mg=20mg); Chlorpheniramine maleate sheet (2 * specification 4mg=8mg); Dexamethasone acetate sheet (2 * specification 0.75mg = 1.5mg); vitamin D2 calcium hydrogen phosphate tablets 2 pieces × specifications 150mg = calcium hydrogen phosphate 300mg (that is, vitamin D2 calcium hydrogen phosphate tablets, each tablet contains calcium hydrogen phosphate 150mg, vitamin D2500 units); bee honeycomb 50mg. Crush vitamin B6 tablets, chlorpheniramine maleate tablets, dexamethasone acetate tablets and vitamin D2 calcium hydrogen phosphate tablets into 150-200 mesh fine powder, mix it with dried and crushed 150-200 mesh honey honeycomb powder Capsules, wherein each capsule weighs about 700mg.

Embodiment 2

[0032] Embodiment 2 (medicine combination): vitamin B6 sheet (2 * specification 10mg=20mg); Chlorpheniramine maleate sheet (1 * specification 4mg=4mg); Dexamethasone acetate sheet (1 * specification 0.75mg = 0.75mg); vitamin D2 calcium hydrogen phosphate tablets 2 pieces × specification 150mg = calcium hydrogen phosphate 300mg (that is, vitamin D2 calcium hydrogen phosphate tablets, each tablet contains calcium hydrogen phosphate 150mg, vitamin D2500 units); bee honeycomb 30mg. Crush vitamin B6 tablets, chlorpheniramine maleate tablets, dexamethasone acetate tablets and vitamin D2 calcium hydrogen phosphate tablets into 150-200 mesh fine powder, mix it with dried and crushed 150-200 mesh honey honeycomb powder Capsules, wherein each capsule weighs about 550mg.

[0033] Typical cases are extracted as follows according to the observation of combination drug therapy of the present invention:

[0034] Case 1: A 57-year-old male patient suffered from allergic rhinitis in 1989 and ...

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Abstract

The invention discloses an anti-allergic rhinitis combination drug. The drug is prepared from the following ingredients by weight: 10-20mg of vitamin B6, 4-8mg of chlorpheniramine maleate, 0.75-1.5mg of dexamethasone acetate, 150-300mg of pharmaceutical grade calcium hydrogen phosphate and 25-75mg of honeybee comb. Tablets containing the proportions of vitamin B6, chlorpheniramine maleate, dexamethasone acetate and calcium hydrogen phosphate are crushed into fine powder of 150-200 meshes, and the fine powder is mixed with dry and crushed honeybee comb powder of 150-300 meshes and the obtained mixture is filled into capsules. According to the drug, drug ingredients of traditional Chinese medicine and Western medicine are reasonably combined, the synergistic effect of the combination drug on allergic rhinitis has a significant treatment effect within a short period. The combination drug is particularly characterized in that the treatment course is short and relapse is unlikely to occur; the combination drug has no dependence or any side effect and is safe, reliable and convenient to use, the former four ingredients of the combination drug provided by the invention are patent medicine, and the honeybee comb and the patent medicine are commercially available.

Description

technical field [0001] The invention relates to a medicine for treating rhinitis, in particular to a combined medicine for resisting allergic rhinitis. Background technique [0002] Allergic rhinitis (Allergic Rhinitis) is a disease caused by inhalation of external allergic antigens, with major symptoms such as nasal congestion, runny nose, and sneezing. There are two main factors for the disease: ①hereditary allergies; ②repeated exposure and inhalation of external allergens. The inhaled antigens that cause this disease include dust mites, dust, animal dander, wind pollen of various trees and grasses, etc. These antigen particles are generally large (5-25 μm), so they can be blocked in the nose. Immediate (type I) allergic reactions occur in the nasal cavity, resulting in a series of manifestations such as congestion, edema, and increased secretion of the nasal mucosa. The immunopathological process is similar to that of inhaled bronchial asthma; , environmental pollution,...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61K9/48A61P11/02A61P37/08A61K31/4402A61K31/4415A61K31/573A61K33/06A61K31/592
Inventor 武文栋武婧妍武科妍
Owner 武文栋
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