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Chinese medicine composition for aiding radiotherapy

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, can solve the problems of electrolyte disturbance, influence on the progress of radiotherapy, influence on the effect of tumor treatment, etc., and achieve the effects of fast curative effect, high effective rate and small side effects

Inactive Publication Date: 2013-11-27
李俊萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Radiation esophagitis: radiation esophagitis is mainly caused by radiation damage to the esophageal mucosa, resulting in local hyperemia, edema, superficial mucosal ulcers, and even transient (temporary) stenosis. When the radiation dose reaches 20-30Gy, Different degrees of radiation esophagitis may occur, and the main symptoms are retrosternal pain, burning sensation, swallowing discomfort, and loss of appetite when eating, which will affect the progress of radiotherapy. In severe cases, dehydration, electrolyte imbalance, and insufficient nutritional intake may occur. Treatment is interrupted. It causes a lot of pain to the patients. In mild cases, the intake of patients is insufficient, and in severe cases, it leads to malnutrition, electrolyte imbalance, and even interruption of radiotherapy, which affects the therapeutic effect of tumors.
Even so, the mucosal reaction of radiotherapy occurs frequently, and there is no effective western medicine for preventing mucosal reaction at present.

Method used

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  • Chinese medicine composition for aiding radiotherapy
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Experimental program
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Effect test

Embodiment 1

[0032] The preparation of embodiment 1 Chinese medicine composition particle 1 of the present invention

[0033] Honeysuckle 25g, licorice 10g, forsythia 10g, chrysanthemum 5g, Ophiopogon japonicus 15g, mint 4g, Qingdai 3g, Poria cocos 10g, Pinellia 5g, tangerine peel 5g, Coptis 2g, Rehmannia glutinosa 10g, Scrophulariaceae 10g, Ophiopogon japonicus 10g, 15g root, 10g sand ginseng, 10g yam, 10g grape leaves, 2g comfrey, 5g light bamboo leaves, 10g trichosanthes. Mix and pulverize; add 2000ml of water relative to the mass of the mixture, decoct for 2 hours, filter the decoction, and concentrate to obtain a paste from which water has been removed, and add 2000ml of alcohol concentration of 65 to the obtained paste %-75% ethanol, stirred for 30 minutes, refrigerated at 0-4°C for 1.5 hours, filtered, recovered ethanol under reduced pressure, added an appropriate amount of medicinal dextrin, mixed evenly, granulated, dried, and crushed into 100-mesh powder. Made into granules (eve...

Embodiment 2

[0034] The preparation of embodiment 2 Chinese medicine composition particle 2 of the present invention

[0035] Honeysuckle 35g, Licorice 15g, Forsythia 15g, Chrysanthemum 10g, Ophiopogon japonicus 25g, Mint 8g, Qingdai 10g, Poria cocos 20g, Pinellia 15g, Chenpi 12g, Coptis 8g, Rehmannia glutinosa 15g, Scrophulariaceae 20g, Ophiopogon japonicus 15g, Reed root 25g, 15g of Adenophora, 15g of Chinese yam, 20g of grape leaves, 10g of comfrey, 15g of light bamboo leaves, 15g of trichosanthes. Mix and pulverize; add 1500ml of water relative to the mass of the mixture, decoct for 2 hours, filter the decoction, concentrate, obtain a paste from which water has been removed, and add 2000ml of alcohol concentration of 65 to the obtained paste %-75% ethanol, stirred for 30 minutes, refrigerated at 0-4°C for 1.5 hours, filtered, recovered ethanol under reduced pressure, added an appropriate amount of medicinal dextrin, mixed evenly, granulated, dried, and crushed into 100-mesh powder. Ma...

Embodiment 3

[0036] Embodiment 3 The preparation of Chinese medicine composition injection of the present invention

[0037] Honeysuckle 30g, Licorice 10g, Forsythia 15g, Chrysanthemum 10g, Ophiopogon japonicus 15g, Mint 5g, Qingdai 6g, Poria cocos 10g, Pinellia 10g, Chenpi 10g, Coptis 5g, Rehmannia glutinosa 10g, Scrophulariaceae 15g, Ophiopogon japonicus 15g, Reed rhizome 20g, 15g of sand ginseng, 10g of Chinese yam, 10g of grape leaves, 8g of comfrey, 10g of light bamboo leaves, 10g of trichosanthes. Mix and crush; soak the medicinal materials in 3500 ℃ water for 2 hours, then decoct on high heat until boiling, then decoct on low heat for 30 minutes, filter, and decoct the filter residue twice, 1 hour each time. Combine the filtrates, concentrate the filtrates, add ethanol until the ethanol content in the filtrate is 70%, filter, recover the ethanol from the filtrate, concentrate to 1g of the original drug per 1ml, refrigerate, filter, fine filter, potting, and sterilize to prepare inj...

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Abstract

The invention provides a Chinese medicine composition for aiding radiotherapy. The Chinese medicine composition comprises honeysuckle, liquorice, fructus forsythiae, chrysanthemum, radix ophiopogonis, mint, indigo naturalis, poria cocos, pinellia ternate, dried orange peel, Coptis chinensis, radix rehmanniae, radix scrophulariae, radix ophiopogonis, reed rhizome, root of straight ladybell, Chinese yam, grape leaf, lithospermum, lophatherum gracile and root of Chinese trichosanthes. When used for treating side effects caused by radiotherapy, the Chinese medicine composition has the advantages of quick treatment effect, high efficiency, little side effect, low price, good tolerance to patients and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating mucous membrane inflammation caused by radiotherapy. Background technique [0002] So far, the effective treatment of tumors is still mainly surgery, chemotherapy, and radiotherapy. However, 80% of patients need to obtain longer survival through radiotherapy and chemotherapy. Radiation therapy, referred to as "radiotherapy", is one of the main means of cancer treatment, with a wide range of applications. The main indications are: 1. Tumors suitable for radiotherapy alone include early and mid-stage nasopharyngeal carcinoma, early and mid-stage maxillary sinus cancer, and early-stage tongue cancer. Cancer, early laryngeal cancer, cervical and middle esophageal cancer, early cervical cancer, early Hodgkin's lymphoma, etc. 2. Tumors suitable for radiotherapy combined with surgery include early and mid-stage intracr...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P29/00A61P1/02A61P1/04
Inventor 李俊萍李兵齐湘杰赵如森周文亮
Owner 李俊萍