Bionic bone/cartilage composite scaffold and preparation technology and fixing method thereof

A technology of composite scaffold and preparation process, applied in the field of manufacturing engineering, to achieve the effect of convenient clinical operation and simple preparation process

Inactive Publication Date: 2013-12-25
XI AN JIAOTONG UNIV
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Problems solved by technology

[0004] The purpose of the present invention is to propose a bionic bone / cartilage composite scaffold and its preparation process and fixation method in view of the existing large area of ​​bone / cartilage defects

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  • Bionic bone/cartilage composite scaffold and preparation technology and fixing method thereof
  • Bionic bone/cartilage composite scaffold and preparation technology and fixing method thereof

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Embodiment Construction

[0022] The present invention will be described in further detail below in conjunction with the accompanying drawings.

[0023] The bionic osteochondral composite scaffold of the present invention and its preparation process are described in detail as follows:

[0024] 1) According to the structure of the patient's osteochondral defect, use reverse engineering and CAD technology to design a bionic osteochondral composite scaffold 4 that matches the defect. The bionic osteochondral composite scaffold 4 includes a bioceramic bone scaffold 2 and a polylactic acid fixation post 3 and hydrogel cartilage scaffold 1 three parts, such as figure 1 As shown, the shape of the bioceramic bone scaffold 2 has a chamfer structure to reduce stress concentration, the chamfer radius is 2-4mm, and the interior has a structure of interconnected channels, which are used for bone ingrowth, and channels are also distributed on the upper surface of the bracket. The channels allow the hydrogel formed ...

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Abstract

The invention provides a bionic bone cartilage composite scaffold and preparation technology and fixing method thereof. According to the structure of the coloboma position of the cartilage of patient, reverse engineering and CAD technology are used for designing the composite scaffold which is matched with the coloboma position; the composite scaffold comprises a biological ceramic bone scaffold, a polylactic acid fixing pile and a hydrogel cartilage scaffold; the light-cured biological ceramic bone scaffold is manufactured by indirect moulding; polylactic acid is perfused in the biological ceramic bone scaffold, and the biological ceramic bone scaffold is cured and polished in a vacuum mold casing machine, and then a biological ceramic / polylactic acid composite scaffold is obtained; the bionic bone cartilage composite scaffold is prepared by light-cured rapid moulding and hydrogel solution; the bionic bone cartilage composite scaffold is placed in the defect position by operation, and is drilled with a support for fixing; bone cement is poured into the support fixing hole, a polylactic acid fixing pile is hit into the fixing hole immediately, after solidification, the implantation of the bone cartilage composite scaffold is completed. The invention is used for repairing large-area bone / cartilage defect with good effect.

Description

technical field [0001] The invention belongs to the field of manufacturing engineering, and in particular relates to a bionic osteochondral composite support for repairing large-area bone / cartilage defects, a preparation process and a fixing method thereof. Background technique [0002] According to statistics, the incidence of osteoarthritis in people over 65 years old is as high as 80%, and the incidence among specific groups such as athletes is 22% to 50%. Trauma, surgical resection (such as tumors), infection, gout and degeneration can cause joint pain. damage. Osteochondral defects above a certain size do not heal spontaneously, although the bone heals well in many clinical situations. Autologous bone grafting and allogeneic bone grafting have certain limitations, and can only be used for local defects, and the effect is not significant in the repair of large-area defects. For some large-area injuries or half-joint injuries, artificial joint replacement requires resect...

Claims

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Application Information

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IPC IPC(8): A61L27/10A61L27/18A61L27/16A61L27/52
Inventor 连芩李涤尘庄佩王臻李常海王玲刘亚雄
Owner XI AN JIAOTONG UNIV
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