Bioglass / polyether-ether-ketone composite materials, method for preparing same, application thereof, bone repair body and bone repair body preparation method

A technology of polyether ether ketone and bioglass, which is applied in the field of polyether ether ketone composite materials, can solve the problems of bone repair materials such as loosening and bone resorption, poor mechanical compatibility, and inability to firmly bond, so as to reduce healing time, good bioactivity and biocompatibility, and shortened bone healing time

Inactive Publication Date: 2014-01-01
EAST CHINA UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome that the existing bone repair materials either have poor mechanical compatibility with bone tissue, easily cause loosening and bone resorption of bone repair materials caused by stress shielding, slow bone healing speed, or lack Biological activity, the defect of being unable to form a firm bond with bone, providing a bioactive glass / polyether ether ketone composite material and its preparation method and application, and a bioactive glass / polyether ether ketone composite material Bone prosthesis and method for its preparation

Method used

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  • Bioglass / polyether-ether-ketone composite materials, method for preparing same, application thereof, bone repair body and bone repair body preparation method
  • Bioglass / polyether-ether-ketone composite materials, method for preparing same, application thereof, bone repair body and bone repair body preparation method
  • Bioglass / polyether-ether-ketone composite materials, method for preparing same, application thereof, bone repair body and bone repair body preparation method

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Effect test

Embodiment 1

[0054] The preparation method of biological glass / polyether ether ketone composite material, it comprises the steps:

[0055] Raw materials: 2kg (20wt%) bio-glass powder (particle size 20μm) and 8kg (80wt%) polyetheretherketone powder (particle size 10μm) were uniformly mixed in a mixer to obtain a mixed powder; Mixed powder injection molding (using a mold of a non-bone prosthetic product), namely; wherein, the injection molding temperature is 360°C; the injection molding pressure is 30MPa. The mechanical properties of the bioglass / polyether ether ketone composite are shown in Table 1.

Embodiment 2

[0057] The preparation method of biological glass / polyether ether ketone composite material, it comprises the steps:

[0058] Raw materials: 3kg (30wt%) bio-glass powder (particle size 20μm) and 7kg (70wt%) polyetheretherketone powder (particle size 10μm) are mixed uniformly in a mixer to obtain a mixed powder; then use injection molding The mixed powder is injection-molded by a machine (using a mold of a non-bone prosthetic product) to obtain it; wherein, the temperature of the injection molding is 380°C; the pressure of the injection molding is 70MPa. The mechanical properties of the bioglass / polyether ether ketone composite are shown in Table 1.

Embodiment 3

[0060] A method for preparing a bone prosthesis, comprising the steps of:

[0061] Raw materials: 4kg (40wt%) bio-glass powder (particle size 20μm) and 5kg (50wt%) polyetheretherketone powder (particle size 10μm) are mixed uniformly in a mixer to obtain a mixed powder; then use injection molding A machine injects the mixed powder into a mold of dog alveolar bone prosthesis to obtain it; wherein, the injection molding temperature is 370° C.; the injection molding pressure is 50 MPa. The mechanical properties of the bone restoration are shown in Table 1.

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Abstract

The invention discloses bioglass / polyether-ether-ketone composite materials, a method for preparing the bioglass / polyether-ether-ketone composite materials, the application of the bioglass / polyether-ether-ketone composite materials, a bone repair body and a bone repair body preparation method. The composite material preparation method comprises the steps that 20-40wt% of 5-20-micron bioglass powder and 60-80wt% 10-20-micron polyether-ether-ketone powder are evenly mixed to obtain mixed powder; the mixed powder is processed and formed, and accordingly the composite materials are prepared. The composite materials have good biological activity and biocompatibility, the composite materials and bone tissues have good mechanical compatibility, and the composite materials can stimulate bone growth, accelerate bone cure, reduce cure time after bone repair materials are implanted, and have bacterium resistance performance. The preparation techniques of the composite materials can be adjusted according to clinic requirements to prepare bone repair bodies of different shapes, difference specifications and different mechanical properties. The bone repair body will not cause inflammatory responses after being implanted, the mechanical property of the bone repair body is matched with human bones, the negative effects that the bone repair materials loosen and bone resorption happens will not be caused, and the bone repair body can meet requirements of clinic for bone repair.

Description

technical field [0001] The invention relates to the field of polyether ether ketone composite materials, in particular to a bioglass / polyether ether ketone composite material and its preparation method and application, and in particular to a bone restoration and its preparation method. Background technique [0002] Modern bone implant materials are increasingly emphasizing the biological functions of implants, and the concept of osseointegration has been widely used in the evaluation of bone implants. At present, titanium-based and ceramic bone implant materials widely used in clinical practice still have their own shortcomings that are difficult to overcome. Bioactive glass (BG) has a history of 40 years since Hench invented it in 1971. It is mainly used as a bone substitute and has been used clinically for nearly 30 years with good results. BG has good biocompatibility and bioactivity, and has been recognized as a suitable permanent implant material all over the world. B...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L61/16C08K3/40A61L27/46A61L31/12B29C45/76B29C67/04
Inventor 魏杰张珏牛云飞董谢平刘昌胜邓玉虎吴钊英蔡亮
Owner EAST CHINA UNIV OF SCI & TECH
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