Method for preparing microcrystalline cellulose at low temperature

A technology for microcrystalline cellulose and cellulose, which is applied in the field of microcrystalline cellulose preparation at low temperature, can solve the problems of increasing production cost, high energy consumption, low yield and the like, and achieves low energy consumption, high crystallinity and simple process. Effect

Active Publication Date: 2014-04-16
HUBEI GEDIAN HUMANWELL PHARMA EXCIPENTS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In summary, the currently reported methods for producing microcrystalline cellulose all have one or more of the following defects: special production equipment (such as extruders, autoclaves, high-pressure steam generation equipment) is required; Carried out, high energy consumption; low solid-liquid ratio, resulting in low yield
These defects increase the cost of production

Method used

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  • Method for preparing microcrystalline cellulose at low temperature
  • Method for preparing microcrystalline cellulose at low temperature

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Add 20L of water to 10Kg of cotton linter pulp with high α-cellulose content after purification and removal of hemicellulose and lignin, and stir to fully swell and infiltrate the cotton linter pulp. Add liquid nitrogen to the swollen linter pulp for rapid cooling and then pulverize it fully. The pulverized cellulose raw material is processed by high-speed shearing in a 10000rpm homogenizer. The slurry after high-speed shearing treatment is dried and pulverized to obtain microcrystalline cellulose. The specific process diagram is as follows figure 1 shown.

Embodiment 2

[0033] 10L of 15wt% hydrochloric acid was added to 10Kg of the purified cotton linter pulp with high α-cellulose content after being purified by the caustic soda method to remove hemicellulose and lignin, so that the cotton linter pulp was fully swollen. The swollen pulp is rapidly cooled with liquid nitrogen until the temperature of the cellulose raw material drops to -10 o After C or below, it is fully pulverized. The pulverized cellulose raw material is processed by high-speed shearing in a 10000rpm homogenizer. The treated slurry is neutralized, washed, dried and pulverized to obtain microcrystalline cellulose.

Embodiment 3

[0035] Add 50L of water to 10Kg of bagasse with high α-cellulose content obtained by purifying and removing the hemicellulose and lignin therein, so as to fully swell the bagasse raw material. -20 o Under the low temperature storage of the swollen bagasse under low temperature, it is fully pulverized. The pulverized cellulose raw material is processed by high-speed shearing in a 10000rpm homogenizer. The treated slurry is dried and pulverized to obtain microcrystalline cellulose.

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Abstract

The invention relates to a method for preparing microcrystalline cellulose at low temperature. The method is characterized by comprising the following steps: (1) completely soaking the cellulose raw material in a soaking solvent, wherein the soaking solvent is water or an acid solution with mass percent concentration not over 15wt% or an oxide solution with mass percent concentration not over 5wt%; (2) freezing the cellulose raw material after the soaking treatment in the step (1), and grinding; (3) performing high-speed shear treatment on the cellulose powder obtained by the grinding in the step (2), and performing aftertreatment on the product after the high-speed shear treatment to obtain the microcrystalline cellulose. The method for preparing microcrystalline cellulose at low temperature provided by the invention can obtain microcrystalline cellulose with different polymerization degrees lower than 350 and relatively high crystallization degree; high-temperature treatment process can be avoided, the energy consumption is low, and the process is simple and green and environment-friendly.

Description

technical field [0001] The invention relates to a method for producing microcrystalline cellulose, in particular to a method for preparing microcrystalline cellulose at low temperature. Background technique [0002] Cellulose is the most abundant natural polymer in nature, widely present in the cell walls of plants and fungi, and is the most extensive and abundant renewable resource. Trees, hemp, wheat straw, straw, bagasse, cotton, etc. are the main sources of cellulose. Among them, cotton has the highest cellulose content, reaching more than 90%. In general wood, cellulose often coexists with hemicellulose and lignin, and the cellulose content is only between 40% and 50%. Cellulose is a kind of β-(1, 4)-D-glucan, which is polymerized by shrinkage of D-glucose with β-(1, 4) glycosidic bonds. There are a large number of hydroxyl groups on its molecular chains, and a large number of hydrogen bond forces between and within the chains make the cellulose molecular chains form ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D21C3/04
Inventor 张阳洋李盛李娟
Owner HUBEI GEDIAN HUMANWELL PHARMA EXCIPENTS
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