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A method for extracting saponin and rhamnose from turmeric

A technology of rhamnose and saponin is applied in the comprehensive utilization of turmeric extracting saponin, and the field of extracting saponin from turmeric can solve problems such as affecting the long-term utilization and development prospect of turmeric, and achieve subsequent resource guarantee, simple operation and simplification. The effect of the production process

Inactive Publication Date: 2016-03-30
北京泛球生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] The purpose of the present invention is to aim at the lack of current turmeric resources and the generation of a large amount of waste, which has seriously affected the long-term utilization and development prospects of turmeric, and the use of current extraction methods will cause a large amount of waste to the environment. The present invention provides a method that utilizes extraction, crystallization and Large-scale production of turmeric saponin from turmeric rhizome by recrystallization method can also increase the yield of turmeric saponin and rhamnose in turmeric

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Weigh 100kg of dried turmeric, crush it through a 20-mesh sieve >90%, add 500kg of 80% ethanol, extract three times, each time for 1.5 hours, combine and concentrate the three turmeric extracts to recover ethanol until there is no alcohol smell, add to the concentrated solution The final concentration of hydrochloric acid solution is 2.5 mol / L, and acid hydrolysis is carried out at 30°C for 90 minutes; the acid hydrolysis solution is filtered to obtain 4.34 kg of crude saponin. Crude saponin was crystallized and recrystallized with petroleum ether, left to stand for 8-12 hours, then filtered, and recrystallized until the crystal color was white, and the crystals were vacuum-dried to obtain 3.68kg of turmeric saponin finished product, which was processed by HPLC. The detection of element content reached 99.42%. The filtrate is adsorbed by AB-8 macroporous resin at 45°C, filtered to obtain macroporous resin particles with adsorbed pigment, washed with distilled water and ...

Embodiment 2

[0042] Weigh 200kg of dried turmeric, crush it through a 20-mesh sieve >90%, add 900kg of 80% ethanol, extract three times, each time for 1.5 hours, combine and concentrate the three turmeric extracts to recover ethanol until there is no alcohol smell, add Hydrochloric acid solution to make the final concentration of 2.5mol / L, carry out acid hydrolysis at 30°C for 90min; filter the acid solution to obtain 8.85kg of crude saponin. Crude saponin was crystallized and recrystallized with petroleum ether, left to stand for 8-12 hours, then filtered and recrystallized until the crystal color was white, and the crystals were vacuum-dried to obtain 7.45kg of turmeric saponin finished product, which was processed by HPLC. The detection of element content reached 99.46%. The filtrate is adsorbed by AB-8 macroporous resin at 45°C, filtered to obtain macroporous resin particles with adsorbed pigment, washed with distilled water and then eluted with 55% ethanol, and the eluate is concentra...

Embodiment 3

[0044] Weigh 400kg of dried turmeric, crush it through a 20-mesh sieve >90%, add 1800kg of 80% ethanol, extract three times, each time for 1.5 hours, combine and concentrate the three turmeric extracts to recover ethanol until there is no alcohol smell, add to the concentrated solution The final concentration of hydrochloric acid solution was 2.5 mol / L, and acid hydrolysis was carried out at 30°C for 90 minutes; the acid solution was filtered to obtain 17.56 kg of crude saponin. Crude saponin was crystallized and recrystallized with petroleum ether, left to stand for 8-12 hours, then filtered and recrystallized until the crystal color was white, and the crystals were vacuum-dried to obtain 13.55kg of turmeric saponin finished product, which was processed by HPLC method. The detection of element content reached 99.63%. The filtrate is adsorbed by AB-8 macroporous resin at 45°C, filtered to obtain macroporous resin particles with adsorbed pigment, washed with distilled water and...

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Abstract

The invention provides a method for producing diosgenin in a large scale from yellow ginger rootstock by utilizing an extraction, crystallization and recrystallization method aiming at the problems that the yellow ginger resources are insufficient at present, lots of wastes are produced, the long-term utilization and development prospects of the yellow ginger are severely influenced, lots of wastes are produced in the environment by adoption of a current extraction method. Moreover, the yield of yellow ginger saponin and rhamnose in the yellow ginger can be improved.

Description

technical field [0001] The invention belongs to the field of natural product processing, and relates to a comprehensive utilization method for extracting saponin from turmeric, and more specifically relates to a method for extracting saponin from turmeric and comprehensively utilizing the waste after extracting saponin Methods. Background technique [0002] Yellow ginger, also known as diosminum shield leaf, is a perennial herb of the genus Dioscrea (Dioscrea. Recorded in "Pharmacopia of the People's Republic of China" (2000 edition), the content of diosgenin (commonly known as saponin) in its rhizomes is 1.1% to 16.15%, which is a synthetic steroid hormone (steroidhormone) drug and steroid An important pharmaceutical and chemical raw material for contraceptives (steroid prophylactic). Herbaceous vines. The rhizomes grow horizontally. Stems slender, glabrous, with longitudinal wrinkles or shallow grooves, sometimes slightly protruding on both sides of the base of branche...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07J71/00C09B61/00C07H3/08C07H1/08
Inventor 王福聚毛鹏董华强
Owner 北京泛球生物科技有限公司