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Medicine for interventional treatment of uterine myoma

A technique for uterine fibroids and interventional treatment, which is applied in the field of drugs for the interventional treatment of uterine fibroids, can solve problems such as skin pain, burning, and acupuncture-like feeling, and achieve the effects of easy acceptance, avoidance of trauma, and high curative effect.

Active Publication Date: 2014-05-07
AFFILIATED HOSPITAL OF NANTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ultrasound-guided high-intensity focused ultrasound treatment of uterine fibroids can inactivate tumors, but patients have skin pain, burning and acupuncture-like sensations, backache and other adverse reactions and complications of varying degrees after surgery

Method used

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Embodiment Construction

[0024] Polycinnamyl alcohol is a polyoxyethylene lauryl ether compound and is an internationally recognized sclerotherapy drug. It has been used internationally to treat varicose veins of the lower extremities and esophagus. After injection of cinnamyl alcohol in the tumor, it can damage the vascular endothelium, promote thrombosis, block the blood vessels, and block the blood supply; especially after injection under the tumor capsule, a layer of dense fibrous tissue is gradually formed in the subcapsule. Causes blood vessel damage and permanent occlusion. Eventually, the tumor shrinks and disappears gradually. At present, there is no report in the world about the treatment of uterine fibroids by intratumoral injection of lauryl alcohol under the guidance of ultrasound. At present, our hospital has been clinically carried out as a routine project. Intratumoral injection of laminol under ultrasound guidance has been used to treat 580 cases of uterine fibroids. It has achieved r...

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Abstract

The invention provides a medicine for interventional treatment of uterine myoma. The medicine belongs to a polyoxyethylene lauryl alcohol ether compound, called lauromacrogol for short; after lauromacrogol is injected under the envelope of an uterine myoma body, a layer of fibre textures is formed in the lower layer of the envelope; blood vessels are injured and permanently occluded by the fibre textures, so that the uterine myoma body is reduced and gradually disappears; uterine myoma is subjected to interventional treatment by utilizing the medicine, so that the functions of an uterus can be intactly retained; in addition, fertilization is not influenced; operative wound and a series of post-operative complications are avoided; the effect of the medicine disclosed by the invention is comparable with operation in the aspect of symptom improvement; by means of interventional treatment of uterine myoma by utilizing the medicine, the medicine disclosed by the invention is small in wound, rapid in recovery, free from being in hospital and easy for patients to accept; compared with the traditional operative treatment, interventional treatment of uterine myoma by utilizing the medicine is simple and convenient; furthermore, blood transfusion is generally unnecessary; the medicine disclosed by the invention has the advantages of being minimally invasive, repeatable, accurate for locating, high in curative effect, rapid in effect, few in complications and the like and brings a good development prospect for clinical treatment of uterine myoma.

Description

Technical field [0001] The invention relates to the innovative application field of cinnamyl alcohol, in particular to a medicine for interventional treatment of uterine fibroids. Background technique [0002] Uterine fibroids are the most common benign tumors in female reproductive organs, with an incidence of about 20%-25% of women of childbearing age. The traditional treatment method is surgical resection, especially for the patients and their families. Psychologically cause permanent damage. In recent years, there are mainly two types of minimally invasive treatment of uterine fibroids: vascular and non-vascular interventional therapy. [0003] Vascular interventional therapy adopts uterine artery catheterization and embolization. Although it can block the blood supply of fibroids and achieve the purpose of reducing fibroids, its technology is complicated. The operation must be performed under X-ray monitoring, with radiation, over 45 years old About 14% of patients cause ova...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/77A61P35/00
Inventor 谢阳桂
Owner AFFILIATED HOSPITAL OF NANTONG UNIV
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