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Persistent hydrogel patch

A hydrogel patch, long-lasting technology, applied in the field of long-lasting hydrogel patches, can solve the problem of affecting the adhesion performance of hydrogel patches, increase the adhesion time of hydrogel patches, and increase the penetration of active ingredients Absorption rate, loss and other issues, to achieve the effect of facilitating transdermal absorption, increasing transdermal absorption efficiency, and increasing hydration

Inactive Publication Date: 2014-07-23
HANGZHOU JIERSI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the problem of the rapid loss of water in the hydrogel layer in the existing hydrogel patch, which affects the adhesion performance of the hydrogel patch product, and the transdermal absorption of active ingredients in the hydrogel patch, Propose a technical solution that can slow down the loss of water, prolong the time of maintaining the adhesiveness of the hydrogel patch and increase the transdermal absorption rate of active ingredients

Method used

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Examples

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Embodiment 1

[0050] This embodiment is a durable hydrogel patch, which is composed of a waterproof composite material with waterproof function as a support layer, a hydrogel layer and an isolation layer. The waterproof composite material is composed of a matrix material and a waterproof material, and the hydrogel layer is coated on the surface of the matrix material of the waterproof composite material; the waterproof material is in the form of a film, and the material can be polyethylene (PE), polyurethane (PU), Thermoplastic polyurethane (TPU), polyester (PET), polypropylene (PP), biaxially oriented polypropylene (OPP), polyvinyl chloride (PVC), polyvinylidene chloride (PVDC), ethylene-vinyl acetate polymer ( EVA), silicone rubber, polyimide (PI) in one or several combinations, wherein the preferred solution is a waterproof material with breathable function, such as polyurethane film (PU); the matrix material is a non-woven fabric , woven fabric, knitted fabric in one. The waterproof ma...

Embodiment 2

[0052] This embodiment is a durable hydrogel patch, which is composed of a waterproof composite material with waterproof function as a support layer, a hydrogel layer and an isolation layer. The waterproof composite material is composed of a matrix material and a waterproof material, and the hydrogel layer is coated on the surface of the matrix material of the waterproof composite material; the waterproof material is in the form of a fluid, and the material can be polyethylene (PE), polyurethane (PU), thermoplastic Polyurethane (TPU), polyester (PET), polypropylene (PP), biaxially oriented polypropylene (OPP), polyvinyl chloride (PVC), polyvinylidene chloride (PVDC), ethylene-vinyl acetate (EVA) ), silicone rubber, polyimide (PI) or a combination of several, wherein the preferred solution is a waterproof material with breathable function, such as polyurethane film (PU); its matrix material is non-woven fabric , woven fabric, knitted fabric in one. The waterproof material and ...

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Abstract

The invention discloses a persistent hydrogel patch. The persistent hydrogel patch is composed of a supporting layer, a hydrogel layer and a separation layer, wherein the supporting layer is made of waterproof compound materials which are composed of waterproof materials and basic materials, the hydrogel layer is coated on the surface of the basic materials of the waterproof compound materials, the basic materials are one of non-woven fabric, knitted fabric and woven fabric, the waterproof materials are one or more of polyethylene, polyurethane, thermoplastic polyurethane, polyester, polypropylene, polyvinyl chloride, polyvinylidene chloride, ethylene-vinyl acetate monomer polymer, silicone rubber, polyimide and the like, are shaped like a film, and are compounded with the basic materials through the processes of film laminating, hot rolling, fabric and powder compounding, hot melt adhesive breathable coating and the like, and the waterproof compound materials are formed. The waterproof materials can be fluid or be compounded with the basic materials through the processes of directly coating, curtain coating and the like, and the waterproof compound materials are formed. According to the persistent hydrogel patch, water in the hydrogel layer can be effectively prevented from being scattered through the supporting layer, and the purposes of lengthening the time of keeping good adhesion performance of the hydrogel layer and increasing the transdermal absorption rate are achieved.

Description

technical field [0001] The invention relates to a durable hydrogel patch, in particular to a hydrogel patch which can prevent water loss, prolong the time for the patch to maintain good adhesion performance, and increase the transdermal absorption rate when used. Background technique [0002] Hydrogel patch, also known as gel ointment ("Chinese Pharmacopoeia" 2010 edition) or called cataplasm plaster ("Chinese Pharmacopoeia 2005 edition"), because it is compared with traditional external plaster, cataplasm has the function of drug administration. The dose is controllable, the drug loading is large, the absorption area is small, the blood drug concentration is stable, it is convenient to use, it can be pasted repeatedly, and it has good air permeability and biocompatibility. One of the dosage forms. [0003] The hydrogel patch is composed of a support layer, a hydrogel layer and an isolation layer. In the existing hydrogel patch products in the market, the support layer is n...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/32A61K47/34
Inventor 舒朝锋
Owner HANGZHOU JIERSI BIOTECH CO LTD
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