Non-contact direct-current induction electrospray ionization device and method

An electrospray ionization, DC induction technology, applied in ion source/gun, parts of particle separator tube, preparation of test samples, etc., can solve the problem of low NSI analysis throughput, difficulty in array analysis, and difficulty in electrical contact and other problems, to achieve the effect of saving sample consumption, improving detection throughput, and facilitating manufacturing

Active Publication Date: 2014-08-06
TSINGHUA UNIV
View PDF9 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the electrical contact problem in NSI limits the use of electrospray technology: 1. The electrode contacts with the spray solution to produce an electrochemical reaction, which affects the measur

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Non-contact direct-current induction electrospray ionization device and method
  • Non-contact direct-current induction electrospray ionization device and method
  • Non-contact direct-current induction electrospray ionization device and method

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0054] Embodiment 1. Non-contact DC induction nano-liter electrospray ionization device

[0055] Such as figure 1 As shown, the non-contact DC induction nano-electrospray ionization device provided by the present invention includes a four-dimensional mobile platform, the four-dimensional mobile platform includes a three-dimensional mobile platform I1 and a workbench connected to the three-dimensional mobile platform I1 The block I2, block I2 and block II3 are connected, and block I2 is connected with a handle 4, which can control block II3 to rotate with the y-axis as the axis. A cantilever I5 is connected to the upper end surface of the block II3. The cantilever I5 can rotate in the xy plane and is made of polytetrafluoroethylene. A two-way joint 6 is fixed on the upper end of the cantilever I5; one end of the wire passes through the two-way joint 6 and is connected to the electrode 7, and the wire is connected to the high-voltage power supply 8. Wherein, the nano electrospray ...

Example Embodiment

[0065] Embodiment 2. Non-contact DC induction nanoelectrospray ionization device for array analysis

[0066] Such as figure 2 As shown, the non-contact DC induction nanoelectrospray ionization device for array analysis provided by the present invention includes a four-dimensional mobile platform including a three-dimensional mobile platform I1 and working with the three-dimensional mobile platform I1 The block I2 connected by the platform, the block I2 and the block II3 are connected, and the block I2 is connected with a rotary handle 4 which can control the block II3 to rotate around the y-axis. A cantilever I5 is connected to the upper end surface of the block II3. The cantilever I5 can rotate in the xy plane and is made of polytetrafluoroethylene. A two-way joint 6 is fixed on the upper end of the cantilever I5; one end of the wire passes through the two-way joint 6 and is connected to the electrode 7, and the wire is connected to the high-voltage power supply 8. The electro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
The inside diameter ofaaaaaaaaaa
Login to view more

Abstract

The invention discloses a non-contact direct-current induction electrospray ionization device and method. The device comprises an electrode, a high-voltage direct-current power supply and a spray head of a nanoliter electric sprayer. The spray head of the nanoliter electric sprayer and the axis of the long and straight wire electrode are in the same straight line. The spray head is located between the electrode and a mass spectrum sample inlet. Electric field lines generated by the tip of the electrode under the excitation of a high voltage penetrate through a conical liquid dialectic before being gathered, so that the intensity of an electric field at the tip of the spray head is greatly enhanced, and liquid to be measured is subjected to electrospray ionization. By means of the non-contact direct-current induction electrospray ionization device and method, the problem that an existing nanoliter electric sprayer can not achieve direct ionization of several samples at the nanoliter grade is solved; meanwhile, the non-contact direct-current induction electrospray ionization device and method can be used for array analysis of the nanoliter electric sprayer. The device is simple in structure, convenient to manufacture and capable of being obtained just by conducting a simple mechanical improvement on the basis of an ion source of a traditional nanoliter electric sprayer; the device can be coupled with an existing commercial mass spectrum instrument, so that the practicability is high; moreover, a lot of problems existing in traditional nanoliter electric sprayers are solved, and the device has wide application prospect and high economic value.

Description

technical field [0001] The invention relates to an electrospray mass spectrometer ionization device and an ionization method, in particular to a non-contact DC induction electrospray ionization device and an ionization method. Background technique [0002] Organic mass spectrometry is an analytical method widely used in the field of life science research that can achieve qualitative, quantitative and structural analysis. Electrospray ionization (ESI) and laser-assisted desorption ionization (MALDI) are the two most typical and widely used ionization methods for organic mass spectrometers. The classic ESI ionization process is described below. The sample solution enters through one section of the capillary, and forms a charged aerosol under the combined action of a strong electric field and sheath gas from the other section. The charge density of the aerosol gradually increases through the solvent volatilization process, resulting in a Coulomb explosion, which eventually io...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): H01J49/16G01N1/28
Inventor 张新荣魏振威张四纯郭成安李艳艳
Owner TSINGHUA UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap