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An asparagus polysaccharide extract product, a preparing method thereof and applications of the extract product

A technology of asparagus polysaccharides and extracts, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problems of undiscovered weight gain and hypoglycemia, achieve good anti-oxidation effects, reduce energy The effect of reducing the consumption and shortening the extraction time

Active Publication Date: 2014-10-08
汕尾市维明生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, medicine has confirmed that DPP-IV inhibitor is a new type of anti-diabetic drug. Clinical results show that this type of drug has a good hypoglycemic effect, and no common adverse reactions such as weight gain and hypoglycemia caused by other diabetes drugs have been found.

Method used

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  • An asparagus polysaccharide extract product, a preparing method thereof and applications of the extract product
  • An asparagus polysaccharide extract product, a preparing method thereof and applications of the extract product
  • An asparagus polysaccharide extract product, a preparing method thereof and applications of the extract product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A kind of asparagus polysaccharide extract, its preparation method is as follows:

[0046] (1) Asparagus is dried and crushed, passed through a 20-mesh sieve, added with a 95% ethanol solution with a volume fraction of 2 times the volume to mass ratio of Asparagus, extracted by slight boiling for 3 hours, filtered to obtain slag, and dried at 60°C to obtain asparagus powder for later use;

[0047] (2) Get 50g asparagus powder and place it in a container, mix evenly with citric acid of pH 2.0 in a mass ratio of 1:30, extract by slight boiling for 3 hours, neutralize with NaOH until the pH value is neutral, filter to obtain Filter residue and first extract;

[0048] (3) Extract the filter residue obtained in step (2) in water by ultrasonic method, ultrasonic power 500W, extraction temperature 40°C, extract for 30 minutes, filter to obtain the second extract, and combine with the first extract obtained in step (2) , to obtain the final extract;

[0049] (4) Ultrafiltrat...

Embodiment 2

[0054] A kind of asparagus polysaccharide extract, its preparation method is as follows:

[0055] (1) Asparagus is dried and pulverized, passed through a 60-mesh sieve, added with a 95% ethanol solution with a volume fraction of 6 times the volume to mass ratio of asparagus, extracted by slight boiling for 2 hours, filtered to obtain slag, and dried at 40°C to obtain asparagus powder for later use;

[0056] (2) Get 50g of asparagus powder and place it in a container, mix it evenly with the malic acid of pH 1.5 in a mass ratio of 1:50, extract by slight boiling for 1 hour, neutralize with NaOH until the pH value is neutral, and filter to obtain Filter residue and first extract;

[0057] (3) Extract the filter residue obtained in step (2) in water with ultrasonic method, ultrasonic power 320W, extraction temperature 60°C, extract for 60 minutes, filter to obtain the second extract, and combine with the first extract obtained in step (2) , to obtain the final extract;

[0058]...

Embodiment 3

[0063] A kind of asparagus polysaccharide extract, its preparation method is as follows:

[0064] (1) Asparagus is dried and pulverized, passed through a 40-mesh sieve, added with a 95% ethanol solution with a volume fraction of 5 times the volume to mass ratio of Asparagus, extracted by slight boiling for 4 hours, filtered to obtain slag, and dried at 60°C to obtain asparagus powder for later use;

[0065] (2) Get 50g of asparagus powder and place it in a container, mix evenly with citric acid of pH 3.5 in a mass ratio of 1:20, extract by slight boiling for 3 hours, neutralize with NaOH until the pH value is neutral, filter to obtain Filter residue and first extract;

[0066] (3) Extract the filter residue obtained in step (2) in water with ultrasonic method, ultrasonic power 640W, extraction temperature 30°C, extract for 20 minutes, filter to obtain the second extract, and combine with the first extract obtained in step (2) , to obtain the final extract;

[0067] (4) Ultr...

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Abstract

The invention belongs to the field of asparagus deep processing, and discloses an asparagus polysaccharide extract product, a preparing method thereof and applications of the extract product. The main monosaccharide components of the extract product are D-galactose and 3,6-anhydro-L-galactopyranose. The extract product is prepared by steps of drying and smashing asparagus, extracting with an organic acid, neutralizing with an alkali, performing ultrasonic extraction, performing ultrafiltration, separating by ion exchange resin, concentrating and performing alcohol precipitation. The preparing method is simple and efficient and suitable for industrial production. The extract product has characteristics of high antioxidation activity, high blood glucose-lowering activity, and high inhibition efficiency for dipeptidyl peptidase IV, and can be used for preparation of blood glucose-lowering medicines or healthcare products.

Description

technical field [0001] The invention belongs to the field of asparagus deep processing, and in particular relates to a polysaccharide extract of asparagus and its preparation method and application. Background technique [0002] Asparagus (Gracialria Lemaneofimrsi) belongs to Rhodophyta, Cedaraceae, Gracaialri (Gracaialri), native to the coast of Shandong Province of my country and Okinawa Island of Japan. Due to the small scale of asparagus farming in the past, the yield is not high and the palatability is poor, so it is rarely eaten directly. It is mainly used to extract agar, and a small part is used as feed for abalone breeding, and it is mostly used as medicine in the folk. "Compendium of Materia Medica" describes that the medicine is sweet in taste and cold in nature, has the effects of softening and resolving phlegm, clearing heat and diuresis, and is used to treat galls and heat, dysuria, and internal heat due to yin deficiency. At the beginning of 2000, the Guangdo...

Claims

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Application Information

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IPC IPC(8): C08B37/00A61K31/715A61P3/06
Inventor 游丽君张云林扶雄郑必胜刘瑞海郭新波崔春
Owner 汕尾市维明生物科技有限公司
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