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Method and composition for removing uremic toxins in dialysis processes

A technology of dialyzer and urease, applied in dialysis system, peritoneal dialysis, other chemical processes, etc., can solve problems and other problems

Active Publication Date: 2014-11-26
BAXTER INT INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This is especially problematic if the dialysis solution is to be reinfused into the patient's peritoneal cavity

Method used

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  • Method and composition for removing uremic toxins in dialysis processes
  • Method and composition for removing uremic toxins in dialysis processes
  • Method and composition for removing uremic toxins in dialysis processes

Examples

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Embodiment Construction

[0101] The present invention relates to methods of providing dialysis therapy. Additionally, the invention relates to systems for providing dialysis. More specifically, in one embodiment, the present invention provides an improved filter cartridge for removing uremic toxins.

[0102]In a preferred embodiment, the present invention relates to systems and assemblies for use in continuous flow peritoneal dialysis procedures. It should be noted, however, that the present invention can be used in a variety of methods for providing dialysis, including hemodialysis and peritoneal dialysis.

[0103] Continuous flow peritoneal dialysis is achieved by continuous infusion of a solution into and drainage from the peritoneum. For example, closed loop or recirculating dialysis can be used, where a solution is continuously recirculated to the patient. This may have the advantage of substantially reducing the amount of solution required for treatment. However, it is necessary to regenerat...

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Abstract

A dialysis system comprising: a sorbent cartridge in fluid communication with at least one of a patient or a dialyzer, the sorbent cartridge including a housing having a zirconium phosphate layer followed by at least one of a urease layer, a zirconium oxide layer, or a carbon layer; a storage container in fluid communication with the sorbent cartridge; a pump in fluid communication sorbent cartridge and the storage container; and a control unit in operable communication with the pump, wherein the control unit is programmed to cause the pump to pump a dialysis fluid to flow (i) in a first direction through the sorbent cartridge, wherein the zirconium phosphate layer is contacted by the dialysis fluid before the at least one of the urease layer, zirconium oxide layer or carbon layer and (ii) in a second direction, reverse from the first direction, through the sorbent cartridge wherein the at least one of the urease layer, zirconium oxide layer or carbon layer is contacted by the dialysis fluid before the zirconium phosphate layer.

Description

[0001] Cross References to Related Applications [0002] This application is related in subject matter to commonly owned Patent Cooperation Treaty application WO 2007 / 089855 A2, which is hereby incorporated by reference in its entirety and is relied upon. technical field [0003] The present invention generally relates to methods of treatment. More specifically, the present invention relates to dialysis procedures. Background technique [0004] Due to disease or injury or other causes, the kidney system may fail. In renal failure of any cause, several physiological disturbances are present. Water, minerals (Na, K, Cl, Ca, P, Mg, SO 4 ) balance and excretion of the daily fixed hydrogen ion metabolic load. Toxic end products of nitrogen metabolism (urea, creatinine, uric acid, etc.) may accumulate in the blood and tissues during renal failure. [0005] The dialysis process has been designed to separate elements in solution by diffusion down a concentration gradient throu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/16B01J20/00A61M1/28
CPCA61M1/287A61M1/1696A61M1/14B01J20/00B01J20/06B01J20/20B01J20/24B01J2220/62B01J20/0292B01J20/28052A61M2209/088A61M1/284A61M1/267A61M1/1694A61M1/28A61M1/3679A61M1/3687
Inventor 苏亚萨·卡如尔
Owner BAXTER INT INC
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