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A kind of Hericium erinaceus mycelium and its cultivation method

The technology of Hericium erinaceus mycelium and cultivation method is applied in the field of Hericium erinaceus mycelium and its cultivation, which can solve the problems of difficult large-scale production, stable industrial quality production, and easy pollution of miscellaneous bacteria, so as to achieve easy contamination and promote Anti-tumor and safety-guaranteed effects

Active Publication Date: 2016-07-27
HUNAN XINHUI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Moreover, due to the problem that traditional solid fermentation is easy to contaminate miscellaneous bacteria, traditional solid fermentation is difficult to produce on a large scale, industrialized, and with stable quality. These are technical problems that need to be solved

Method used

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  • A kind of Hericium erinaceus mycelium and its cultivation method
  • A kind of Hericium erinaceus mycelium and its cultivation method
  • A kind of Hericium erinaceus mycelium and its cultivation method

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Embodiment 1

[0025] (1) Cultivation of Hericium erinaceus mycelium

[0026] (1) Mother strain culture: prepare the mother culture medium, the ingredients are 400 grams of potato, 42 grams of kana gum, 30 grams of glucose, 10 grams of yeast extract, 10 grams of peptone, 2 grams of potassium dihydrogen phosphate, dihydrogen phosphate Potassium 1g, magnesium sulfate 1g, vitamin B 1 80 mg, Vitamin B 2 40 mg, boil the mother culture medium, put it into a test tube, inoculate Hericium erinaceus strains into the mother culture medium, place it in an incubator for cultivation, and cultivate it at 25°C for 10 days until the slant of the test tube is full of bacteria , that is, the mother strain. The Hericium erinaceus strains used were purchased from Fujian Sanming Fungi Research Institute.

[0027] (2) Original seed culture: Prepare the original seed medium, the ingredients are 70 grams of cottonseed hulls, 20 grams of wheat bran, and 10 grams of corn flour, mix well, bottle, plug the bottle mo...

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Abstract

The invention discloses Hericium erinaceus mycelium and a cultivation method thereof. It contains relatively high content of amino acids and vitamins, and also contains 7 kinds of cyclic dipeptides, ergosterol and carboxymethyl cellulase activity. The 7 kinds of cyclic dipeptides are respectively For: cyclic (valine-tyrosine), cyclic (leucine-tyrosine), cyclic (phenylalanine-tyrosine), cyclic (phenylalanine-phenylalanine), cyclic (leucine‑leucine), ring (leucine‑alanine), ring (valine‑alanine). The cultivation method includes mother strain cultivation, original strain cultivation, cultivar strain cultivation, a "directed" biotransformation process and a secondary "directed" biotransformation process. The cultivated Hericium erinaceus mycelium has good anti-tumor effect.

Description

technical field [0001] The invention relates to the field of microbial engineering, in particular to Hericium erinaceus mycelia containing seven kinds of cyclic dipeptides, ergosterol and carboxymethyl cellulase activity and a cultivation method thereof. Background technique [0002] Hericium erinaceus mycelium is the mycelium obtained by targeted biotransformation of the fungus Hericium erinaceus (Bull.) Pers. It has been used to treat gastrointestinal diseases for more than 2000 years. A series of small molecules Compounds such as erinacines are believed to have neuroregenerative properties and can repair damaged nerve tissue through the blood-brain barrier, and Hericium erinaceus are also anti-ulcer, anti-inflammatory, anti-microbial, immunomodulatory, improve liver function, anti-aging, lower blood sugar and Blood lipids, improve anti-hypoxic ability, increase cardiac output, and improve circulation and other effects, medical preparations containing Hericium erinaceus ar...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/14A61P35/00C12R1/645
Inventor 何述金常耀台
Owner HUNAN XINHUI PHARMA
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