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A kind of therapeutic agent for duodenal ulcer and preparation method thereof

A duodenal ulcer and therapeutic agent technology, applied in the field of duodenal ulcer therapeutic agent and its preparation, to achieve the effects of strong drug efficacy, shortened treatment cycle, and reduced treatment cost

Active Publication Date: 2017-03-29
GUIZHOU TELIDA NANO CARBON SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, it has not been reported that nano-carbon powder is directly used in the medical field to treat duodenal ulcer. For this reason, through long-term exploration and research, this researcher has studied the use of nano-carbon powder in the treatment of duodenal ulcer and its ten applications. The field of drug treatment for duodenal ulcer provides a new idea

Method used

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  • A kind of therapeutic agent for duodenal ulcer and preparation method thereof

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Embodiment 1

[0019] A kind of preparation method of duodenal ulcer therapeutic agent, takes by weighing 3g glucose powder, it is stirred and dissolved in 97ml of water, and the stirring speed of stirring is 30r / min, after stirring for 20min, stand-by; Then weigh sodium chloride 0.8g, and stirred and dissolved in 99.2ml of water, fully dissolved, and then used; then weighed 0.03g of sodium dihydrogen phosphate, and dissolved it in 99.97ml of water, stirred and mixed evenly; then the above three solutions Mix evenly in equal proportions and wait for use; then measure the above solution, weigh 90.7g of the solution and put it in a 250ml beaker, then add 7g of sucrose ester to the beaker, and use a stirrer to stir at a stirring speed of 90r / min for 20min After that, it is placed in an environment with a temperature of 40°C for 20 minutes, and then it is ultrasonically treated for 0.4 hours; then it contains 95% of the nano-scale 5nm, and the dispersibility in water is 99.19%. powder into it, a...

Embodiment 2

[0021] A kind of preparation method of duodenal ulcer therapeutic agent, takes by weighing 6g glucose powder, it is stirred and dissolved in 94ml water, and the stirring speed of stirring is 40r / min, after stirring for 30min, stand-by; Then weigh sodium chloride 1g, and stirred and dissolved in 99ml of water, fully dissolved, and then used; then weighed 0.041g of sodium dihydrogen phosphate, and dissolved it in 99.959ml of water, stirred and mixed evenly; Mix evenly and set aside; then measure the above solution, weigh 94.35g of the solution and place it in a 250ml beaker, then add 3g of sucrose ester to the beaker, and use a stirrer to stir at a stirring speed of 70r / min for 40min. Then place it in an environment with a temperature of 60°C and let it stand for 30 minutes, and then use ultrasonic treatment for 0.9 hours; then take 96% of the nano-sized 4nm nano-carbon powder with a dispersibility of 99.19% in water and add Wherein, when adjusting the mass percentage of nano-ca...

Embodiment 3

[0023] A kind of preparation method of duodenal ulcer therapeutic agent, takes by weighing 4g glucose powder, it is stirred and dissolved in 96ml water, and the stirring speed of stirring is 35r / min, after stirring for 25min, stand-by; Then weigh sodium chloride 0.9g, and stirred and dissolved in 99.1ml of water, fully dissolved, and then used; then weighed 0.035g of sodium dihydrogen phosphate, and dissolved it in 99.965ml of water, stirred and mixed evenly; then the above three solutions Mix evenly in equal proportions and wait for use; then measure the above solution, weigh 93.15g of the solution and place it in a 250ml beaker, then add 5g of sucrose ester to the beaker, and use a stirrer to stir at a stirring speed of 80r / min for 30min After that, it is placed in an environment with a temperature of 50°C for 25 minutes, and then it is ultrasonically treated for 0.7 hours; then it contains 97% of the nano-scale 3nm, and its dispersibility in water is 99.19%. powder into it,...

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Abstract

The invention relates to the technical field of medicine for the digestive system, in particular to a duodenal ulcer therapeutic agent and a preparation method thereof. 0.05-0.3% mass percentage of nano-carbon powder; improve the cure rate and efficiency of duodenal ulcer, and provide a new drug choice for the field of duodenal medicine; The nano-scale is selected so that the nano-carbon powder can play a therapeutic role, and then it is dispersed and mixed with the isotonic solution of the human body to obtain a duodenal treatment with better therapeutic effect than the positive drug omeprazole. The drug can greatly shorten the treatment period of duodenal ulcer, reduce the treatment cost to a great extent, and the drug has side effects and strong efficacy.

Description

technical field [0001] The invention relates to the technical field of digestive system medication, in particular to a therapeutic agent for duodenal ulcer and a preparation method thereof. Background technique [0002] Gastric and duodenal ulcers refer to localized round or oval full-thickness defects of gastric and duodenal mucosa, the muscularis mucosae is penetrated, and fibrous scars inevitably remain after healing, with a layer of epithelium on the surface Overlying, the muscularis mucosa cannot regenerate. The etiology can be summed up as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it has been considered that the formation of ulcers has an important relationship with Helicobacter pylori infection in the stomach. [0003] In the prior art, most of the chemotherapy methods used in the treatment of the above-mentioned diseases have relatively large side effects, l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/44A61P1/04
Inventor 聂瑛洁李力
Owner GUIZHOU TELIDA NANO CARBON SCI & TECH