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Quaternary ammonium salt type antibacterial hand washing solution

An antibacterial hand sanitizer, quaternary ammonium salt technology, applied in the direction of topical antibacterial agents, cosmetic preparations, pharmaceutical formulations, etc. good stability

Active Publication Date: 2015-01-28
江苏德鲁克生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, hand sanitizers with quaternary ammonium salts as antibacterial ingredients are extremely rare in the market, and traditional antibacterial agents are generally chlorine and phenol compounds. Although they have good antibacterial effects, their harm to the human body and the environment is also unacceptable. ignore
In January 2014, Liu He pointed out in an article on environmental science and technology that substances containing benzene rings will reduce the degradation ability of microorganisms to a greater extent, which means that hand sanitizers will stay in nature for a long time after being used by people and are difficult to degrade. It will even destroy the original degradation ability of microorganisms, thus causing secondary pollution
[0003] In recent years, there have also been related researches on the promotion of natural plant essences as antibacterial ingredients, such as: honeysuckle, tea tree oil, aloe and other Chinese herbal medicines, but the cost and the production of these natural plant extractions still trouble everyone, and the traditional natural plant extraction Generally, a large amount of organic solvents are used, such as methanol, acetone, diethyl ether, etc., which is not only costly, but also has a certain impact on the environment, so it has not been widely promoted in the end.

Method used

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  • Quaternary ammonium salt type antibacterial hand washing solution
  • Quaternary ammonium salt type antibacterial hand washing solution
  • Quaternary ammonium salt type antibacterial hand washing solution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: (weight percent)

[0014] Sodium lauryl polyoxyethylene ether sulfate 0.667%, quaternary ammonium salt 1.333%, cocamidopropyl betaine 20%, alcohol ether sulfosuccinic acid monoester disodium salt 0.15%, coconut oil diethanolamide 1.5% , preservative DMDMH 0.1%, essence 0.2%, distilled water balance. The components are mixed and stirred evenly, the pH is adjusted to 6.5 with citric acid, and the appearance color is adjusted by adding water-soluble pigment.

Embodiment 2

[0015] Embodiment 2: (percentage by weight)

[0016] Myristyl Methyl Dihydroxyethyl Ammonium Bromide 0.667%, Quaternary Ammonium Salt 1.333%, Cocamidopropyl Betaine 20%, Alcohol Ether Sulfosuccinate Monoester Disodium Salt 0.15%, Coconut Oil Diethyl Ethanol Amide 1.5%, preservative DMDMH 0.1%, essence 0.2%, distilled water balance. The components are mixed and stirred evenly, the pH is adjusted to 6.5 with citric acid, and the appearance color is adjusted by adding water-soluble pigment.

Embodiment 3

[0017] Embodiment 3: (weight percent)

[0018] Cetyl Methyl Dihydroxyethyl Ammonium Bromide 0.667%, Quaternary Ammonium Salt 1.333%, Cocamidopropyl Betaine 20%, Alcohol Ether Sulfosuccinate Monoester Disodium Salt 0.15%, Coconut Oil Diethyl Ethanol Amide 1.5%, preservative DMDMH 0.1%, essence 0.2%, distilled water balance. The components are mixed and stirred evenly, the pH is adjusted to 6.5 with citric acid, and the appearance color is adjusted by adding water-soluble pigment.

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PUM

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Abstract

The present invention discloses a quaternary ammonium salt type antibacterial hand washing solution, which comprises, by weight, 0.4-0.8% of sodium lauryl polyoxyethylene ether sulfate, 1-2% of a quaternary ammonium salt, 15-25% of cocamidopropyl betaine, 0.1-0.2% of MES (AESS), 1-2% of coconut oil diethanolamide, 0.05-0.15% of a preservative, 0.1-0.5% of essence, and the balance of distilled water, wherein the pH value is 6.5-7.0. According to the quaternary ammonium salt type antibacterial hand washing solution, the anionic surfactant and the cationic surfactant can stably exist in the compounding system, and the solubility is good when the use amount of the one surfactant is more than the use amount of the other surfactant, such that the coagulation is not easily produced. The quaternary ammonium salt type antibacterial hand washing solution has characteristics of good stability, high escherichia coli killing rate, high staphylococcus aureus killing rate, and foaming property achieving the market level.

Description

technical field [0001] The invention relates to a quaternary ammonium salt type antibacterial hand sanitizer. Background technique [0002] In November 1999, Zusi launched the first bottle of hand sanitizer in my country, but failed because it did not meet consumer demand. In 2000, Blue Moon learned from the former and found a breakthrough in consumer demand. During the period of SARS, people had higher and higher requirements for hand sanitizers. The development of hand sanitizers has evolved from ordinary decontamination type to antibacterial effect, low stimulation, and harmless to the environment. At present, the common antibacterial hand sanitizers on the market in my country, such as Blue Moon, Dido, Valus, and Safeguard, among which the main antibacterial ingredients are α-phenylphenol, p-chloro-m-xylenol, DMG antimicrobial factor, PCMX However, in hospital operating rooms with high antibacterial performance requirements, the more hand-harming bromogeramine disinfecta...

Claims

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Application Information

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IPC IPC(8): A61K8/86A61K8/40A61Q19/10A61P31/02
Inventor 郑成黎敏珊毛桃嫣
Owner 江苏德鲁克生物科技有限公司
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