Sample extraction, purification and concentration integrated device and sample pretreatment method

Abstract

An integrated device for sample extraction, purification and concentration, including a solvent system, a sample extraction system, a sample purification system, a sample concentration system and a computer; wherein: the solvent system provides necessary solvents for the sample extraction and purification steps; the sample extraction system adopts advanced After pre-freezing the sample with liquid nitrogen, the method of organic solvent extraction is carried out. The extract is stored in the buffer pool and injected into the sample purification system by high-purity nitrogen. The sample purification system includes acid silica gel column, composite silica gel column, alumina column, Commercial packed columns such as activated carbon columns can be used for single-column and multi-column series purification; the sample concentration system uses the heat generated by resonance of nano-gold or nano-silver particles to evaporate and concentrate the sample solution, and the concentrated solution is transferred to the sample receiving bottle. Sample pretreatment process.

Description

technical field [0001] The invention relates to an instrument structure for automatic operation of extraction, purification and concentration of persistent organic pollutants in solid samples, more specifically, an integrated device for sample extraction, purification and concentration. [0002] The present invention also relates to a method for sample pretreatment using the above-mentioned device. Background technique [0003] Persistent organic pollutants (POPs) are a class of environmental pollutants that have received widespread attention in recent years. Such pollutants generally have strong environmental persistence, biological toxicity, bioaccumulation ability and long-distance migration ability, so the scientific issues related to them have become research hotspots in the field of environmental science. [0004] The content level of POPs in the environment is generally low, usually ppb~ppt level (10 -9 ~10 -12 ), which poses great challenges to instrumental analys...

AI Technical Summary

Problems solved by technology

At present, the development of analytical instruments can basically meet the analysis and detection of such low-level pollutants. However, when it comes to actual environmental samples, the success of the analysis is often affected by factors such as sample pretreatment technology and capabilities.

Sample pretreatment usually includes steps such as sample extraction, purification, and concentration. Related sample pretreatment technologies have developed rapidly in recent years. However, for POPs sample pretreatment, especially purification technology, the traditional method of manually packing chromatographic columns is still mainly used. , the workload of the operator is heavy, and the sample purification cycle is long

Fluid Management Systems (FMS) of the United States has developed a pressure fluid extraction device combined with automatic sample column purification equipment. Compared with its extraction device, the sample automatic column purification equipment developed by FMS has been recognized by the market. However, the combination of the two The technology used is still limited by the fact that the pressure control of the extraction device is not intelligent enough, and the extraction operation is relatively cumbersome. Currently, there are few market applications.

In addition, the accelerated solvent extraction (ASE) system developed by American Dionex (now acquired by Thermo fisher) has been widely recognized in the market, but it can only perform a separate extraction operation on samples; American J 2 The PrepLinc system developed by Scientific has been able to complete the automatic purification and concentration of samples, but there is no sample extraction system

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