Monomer flavor Mal-Ile used for cigarettes as well as preparation method and application thereof

A technology of monomers and fragrances, applied in the field of preparation and new type of tobacco monomer fragrance Mal-Ile, achieving significant industrial application value and popularization and application, excellent physical moisturizing effect, and high yield effect

Active Publication Date: 2015-02-11
CHINA TOBACCO HENAN IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to increase the moisture content of shredded tobacco during processing and improve the processing resistance of shredded tobacco. The maintenance of moisture content in shredded tobacco and the improvement of sensory comfort in cigarettes are not ideal

Method used

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  • Monomer flavor Mal-Ile used for cigarettes as well as preparation method and application thereof
  • Monomer flavor Mal-Ile used for cigarettes as well as preparation method and application thereof
  • Monomer flavor Mal-Ile used for cigarettes as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method for tobacco monomer spice Mal-Ile, comprising the steps of:

[0029] Add 1 gram of maltose, 1.5 mL of dimethylformamide, and 2.8 mL of anhydrous methanol into a three-neck flask equipped with a thermometer and a condenser, reflux at 76°C for 20 minutes, then add 0.138 grams of isoleucine and reflux for another 20 minutes. Finally, 0.035 g of strong acidic ion exchange resin and 0.249 g of kaempferol were added for reflux reaction for 2.0 h; after the reaction, 0.395 g of the target product in the form of white crystals was obtained by silica gel column chromatography and recrystallization. Among them, the eluent used for column chromatography separation is a mixed solution composed of n-butanol, glacial acetic acid and water, the volume ratio of the three is 6:1:1, and the chromogenic agent is ninhydrin ethanol solution; the solvent used for recrystallization It is a mixed solution of absolute ethanol and absolute methanol with a volume ratio of 1:1...

Embodiment 2

[0031] A preparation method for tobacco monomer spice Mal-Ile, comprising the steps of:

[0032] Add 1 gram of maltose, 3.6 mL of dimethylformamide, and 2.0 mL of anhydrous methanol into a three-necked flask equipped with a thermometer and a condenser, reflux at 85°C for 35 minutes, then add 0.256 grams of isoleucine and reflux for another 35 minutes. Finally, 0.053 g of strong acidic ion exchange resin and 1.019 g of kaempferol were added for reflux reaction for 6.0 h; after the reaction, 0.845 g of the target product in the form of white crystals was obtained by silica gel column chromatography and recrystallization. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

[0033]

Embodiment 3

[0035] A preparation method for tobacco monomer spice Mal-Ile, comprising the steps of:

[0036] Add 1 gram of maltose, 3.9 mL of propylene glycol and 1.7 mL of anhydrous methanol into a three-necked flask with a thermometer and a condenser tube, reflux at 89°C for 45 minutes, then add 0.396 grams of isoleucine and reflux for another 45 minutes, and finally add 0.068 grams of Strongly acidic ion exchange resin and 1.245 g of kaempferol were refluxed for 8.0 h; after the reaction, separated by silica gel column chromatography and recrystallized to obtain 0.584 g of the target product in the form of white crystals. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

[0037] (1) Structural characterization of the target product

[0038] Through infrared spectroscopy (IR), high-resolution mass spectrometry (HR-MS), carbon nuclear magnetic resonance spectroscopy ( 13 C-NMR) carried out the structural charac...

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PUM

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Abstract

The invention relates to a novel monomer flavor Mal-Ile used for cigarettes as well as a preparation method and application thereof. A structural formula of Mal-Ile is shown in the specification. Through physical humectant property tests of cigarettes and inner sensory quality evaluation of finished cigarettes, the monomer flavor is found to be capable of obviously improving the physical humectant properties of cut tobaccos, also have the function of obviously improving the sensory quality of the cigarettes and be capable of reducing the irritation and offensive odors of the cigarettes and improving the mellowness and fullness of the cigarette smoke.

Description

technical field [0001] The invention belongs to the field of flavors and fragrances and tobacco processing, and in particular relates to a novel monomer fragrance Mal-Ile for cigarettes, a preparation method and an application thereof. Background technique [0002] As people pay more and more attention to smoking and health problems, while the tar content of cigarettes is further reduced, the comfort of cigarettes becomes worse, which is mainly reflected in the loss of water dispersion of shredded tobacco, low moisture in mainstream smoke, high irritation, and dry mouth. And phlegm etc. At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to increase the moisture content of shredded tobacco during processing and improve the processing resistance of shredded tobacco. The maintenance of moisture content of shredded tobacco and the improvement of sensory comfort of cigarettes a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H7/02C07H1/00A24B15/40
Inventor 芦昶彤陈芝飞孙志涛李耀光罗灿选赵志伟李成刚
Owner CHINA TOBACCO HENAN IND
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