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Composition capable of improving joints and increasing bone mineral density and preparation method of composition

A technology for increasing bone density and composition, which is applied in the field of joint improvement and bone density increasing composition and its preparation, which can solve the problems of low extraction rate of active ingredients, unsatisfactory bone density curative effect, and simple Chinese herbal medicine formula. The effects of rich lattice structure, improved growth and reproductive ability, and enhanced ion exchange capacity

Inactive Publication Date: 2015-04-22
北京东方兴企食品工业技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The curative effect of the above-mentioned disclosed products for increasing bone density is far from satisfactory, and has the following defects: 1) the Chinese herbal medicine extract used has a simple formula and incomplete synergistic effect; 2) the Chinese herbal medicine extract is prepared by a traditional method, and the extraction rate of active ingredients 3) The calcium source disclosed in the product is mainly inorganic calcium or organic calcium such as calcium carbonate, which are all extracted, separated or synthesized by chemical methods. prepared, there are certain food safety hazards, the application of calcium carbonate will have side effects on patients who are prone to stomach distension, and the calcium source is single in nature; 4) the stability problem of the product is not well solved
[0011] Applying the natural food raw material - Zhonghua Calcium Fruit to products that increase bone density can not only provide products with rich natural plant-based calcium sources and other nutrients with high food safety, high calcium content, high calcium utilization rate and absorption rate , and will also drive the development of animal husbandry and other industries to achieve sustainable development. At present, there is no report on the application of Chinese calcium fruit to increase bone density products

Method used

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  • Composition capable of improving joints and increasing bone mineral density and preparation method of composition
  • Composition capable of improving joints and increasing bone mineral density and preparation method of composition

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Effect test

Embodiment 1

[0063] Embodiment 1 raw material preparation

[0064] 1. Preparation of herbal extracts

[0065] The preparation method of the Chinese herbal medicine extract comprises the following steps: in parts by weight, weigh 8 parts of Rhizoma Drynariae, 10 parts of Epimedium, and 5 parts of Lycium barbarum; put them in an ultrasonic cleaning machine filled with 0.2% sodium bicarbonate solution Wash at 200W, 30KHz for 12 minutes, drain, crush the above-mentioned Chinese herbal medicine to a particle size of less than 2mm, mix evenly in a container and add 5 times the weight of water to obtain a mixed material, control the temperature at 80°C for 3h, then cool down to 45°C ℃, adjust the pH value to 4 with lactic acid, and carry out microwave extraction under the conditions of power 200W and frequency 2000Hz, wherein, the total time of each microwave irradiation is 70s, and the interval irradiation is carried out: irradiation 10s, interval 10s, such irradiation 10s At the same time, und...

Embodiment 2

[0074] A powder capable of improving joints and increasing bone density, mainly prepared from the following raw materials in parts by weight:

[0075] 35 parts of calcium lactate, 20 parts of Chinese herbal medicine extract, 20 parts of calcium fruit extract, 10 parts of glucosamine sulfate potassium salt, 8 parts of chondroitin sulfate, 7 parts of milk calcium, 5 parts of casein calcium peptide, 4.8 parts of magnesium lactate, two 3 parts of methyl sulfone, 2.8 parts of grape seed extract, 0.21 parts of zinc lactate;

[0076] The powder for improving joints and increasing bone density also includes the following auxiliary materials in parts by weight:

[0077] 14 parts of maltodextrin, 11 parts of D-mannitol, 17 parts of modified dietary fiber, 5 parts of guar gum, 1 part of hydroxypropyl methylcellulose, 1 part of citric acid, 0.5 parts of silicon dioxide, steviol glycoside 0.08 parts.

[0078] The preparation method comprises the following steps:

[0079] 1) According to...

Embodiment 3

[0084]A powder capable of improving joints and increasing bone density, mainly prepared from the following raw materials in parts by weight:

[0085] 20 parts of calcium lactate, 12 parts of Chinese herbal medicine extract, 15 parts of calcium fruit extract, 5 parts of glucosamine sulfate potassium salt, 5 parts of chondroitin sulfate, 2 parts of milk calcium, 2.5 parts of casein calcium peptide, 3 parts of magnesium lactate, two 2 parts of methyl sulfone, 1.5 parts of grape seed extract, 0.15 parts of zinc lactate;

[0086] The powder for improving joints and increasing bone density also includes the following auxiliary materials in parts by weight:

[0087] 5 parts of maltodextrin, 5 parts of D-mannitol, 5 parts of modified dietary fiber, 2 parts of guar gum, 0.5 part of hydroxypropyl methylcellulose, 0.5 part of citric acid, 0.2 part of silicon dioxide, steviol glycoside 0.01 copies;

[0088] The preparation method comprises the following steps:

[0089] 1) According to ...

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Abstract

The invention discloses a composition capable of improving joints and increasing bone mineral density and a preparation method of the composition. A Chinese herbal medicine extract which is refined from Chinese dwarf cherry by a modern extraction technology is scientifically compounded with other raw materials capable of increasing the bone mineral density, thus calcium absorption is effectively promoted from a plurality of aspects through comprehensive scientific combination and synergistic effect; cartilago articularis is repaired and rebuilt; synovial fluid is promoted to produce, synthesis of collagen in cartilago articularis matrix is promoted; further degeneration of cartilage is prevented; the osteoclast effect is indirectly weakened; re-absorption of bone is inhibited; the bone calcium content is increased; and the biomechanical property of the bone is improved, so that the composition has a good effect of increasing the bone mineral density. The integration and the biological stability of the composition can be further extracted by a microwave drying technology in the preparation method; the oxidation resistance of a grape seed extract in the raw material is improved; high adsorption and embedding effects of a dietary fiber and the antifungal properties of a Chinese herbal medicine extract are improved; and finally the composition which is efficient, safe, nutrient and stable, and has the function of increasing the bone mineral density is prepared.

Description

technical field [0001] The invention relates to a composition, in particular to a composition capable of improving joints and increasing bone density and a preparation method thereof. Background technique [0002] In recent years, osteoporosis has become a disease that seriously threatens human health worldwide, and it has attracted increasing attention. At present, there are more than 200 million osteoporosis patients in the world, and its incidence rate has jumped to the seventh among various common diseases in the world. It is generally believed that in the West, 1 in 4 women or 1 in 8 men suffers from this disease. In the United States, there are 10 million people with osteoporosis and 18 million people with low bone mass who may develop osteoporosis. There are 9-10 million elderly people suffering from osteoporosis in Japan, accounting for about 9% of the total population of Japan. It is estimated to affect approximately 75 million people in the United States, Europe...

Claims

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Application Information

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IPC IPC(8): A61K38/17A23L1/09A61P19/10A61K36/73A61K36/87A61K36/815A61K36/296A61K36/11A61K31/737A61K31/7008A61K31/10A61K31/315A61K31/19A23L33/105A23L33/21
Inventor 房克敏赵军蒋峰
Owner 北京东方兴企食品工业技术有限公司
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