Pharmaceutical preparation for treating pharyngeal ulcer

A technology for pharmaceutical preparations and ulcers, applied in the field of pharmaceutical preparations for treating pharyngeal ulcers, can solve the problems of reduced treatment effect, foreign body irritation in patients, nausea, vomiting, etc., and achieves the effects of long residence time, strong adhesion and increased curative effect

Inactive Publication Date: 2015-04-29
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Moreover, the position of the pharyngeal ulcer is special. If the common oral medicine film covers the pharyngeal ulcer, it will cause strong foreign body stimulation to the patient, and even cause symptoms such as nausea and vomiting, which is difficult to treat; and the powd

Method used

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  • Pharmaceutical preparation for treating pharyngeal ulcer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Raw material weight ratio is:

[0037] Garlic extract 0.15g, aloe extract 1.25g, tetracaine hydrochloride 1.0g, tragacanth gum 1.0g, glycerin 70ml, purified water 50ml.

[0038] Raw material source:

[0039] Garlic extract (Garlic extract) is commercially available, light yellow fine powder, containing 2% allicin (determined by GC method), product of Xi'an Ruilin Biotechnology Co., Ltd.;

[0040] Aloe Barbadensis Miller, commercially available, light yellow powder, containing 99% aloin (as determined by HPLC), a product of Changsha Huajin Biotechnology Co., Ltd.;

[0041] Tetracaine hydrochloride (Tetracaine hydrochloride) is commercially available, white crystalline powder, content 99%, the product of Beijing Yanjing Pharmaceutical Co., Ltd.;

[0042]Gum tragacanth (Gummi Tragacanthae), white or yellow-white powder or translucent flakes, is the gum exuded from the dry branches of the leguminous plant Astra—galus gummifer Labill. It is obtained by drying. It mainly ...

Embodiment 2

[0085] Raw material weight ratio is:

[0086]Garlic extract 0.051g, aloe extract 0.5g, tetracaine hydrochloride 0.5g, tragacanth gum 0.75g, glycerin 50ml, purified water 30ml. All the other are the same as embodiment one.

Embodiment 3

[0088] Raw material weight ratio is:

[0089] Garlic extract 0.1g, aloe extract 1.0g, tetracaine hydrochloride 0.75g, tragacanth gum 0.75g, glycerin 60ml, purified water 40ml.

[0090] All the other are the same as embodiment one.

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Abstract

The invention discloses a pharmaceutical preparation for treating pharyngeal ulcer. The pharmaceutical preparation is prepared from 0.05-0.15g of garlic extract, 0.5-1.25g of aloe extract, 0.5-1.0g of tetracaine hydrochloride, 0.5-1.0g of tragacanth, 50-70ml of glycerin and 30-50ml of purified water. The preparation method comprises the following steps: adding the aloe extract and tragacanth into glycerin for grinding, and wetting; adding the garlic extract and the tetracaine hydrochloride into the purified water, boiling and dissolving; uniformly mixing, grinding into colloid, supplementing the residual purified water, stirring into a homogeneous phase, split charging, sterilizing at the temperature of 100 DEG C for 30 minutes, thereby obtaining the gel so as to be applied to a pharmaceutical preparation for treating pharyngeal ulcer. According to clinical verifications of 80 cases, the pharmaceutical preparation is exact in curative effect of treating pharyngeal ulcer and does not have any adverse reaction. The pharmaceutical ingredients can be effectively remained at the ulcer part for a long time, the curative effect is reliable, the medicine can be daubed by non-professional persons, the inconvenience that nebulizer treatment can be performed by virtue of medical equipment only is avoided, and the pharmaceutical preparation is simple and feasible to use and safe.

Description

technical field [0001] The invention relates to a pharmaceutical preparation, in particular to a pharmaceutical preparation for treating pharyngeal ulcer, its composition, preparation method and application. Background technique [0002] Ulcer is a localized defect or ulceration of skin or mucous membrane surface tissue, the surface is often covered with pus, necrotic tissue or scab, and scars are left after healing, which can be caused by infection, trauma, nodules or tumor ulceration, etc. Its size, shape, depth, and development process are also inconsistent. Often associated with chronic infection, may not heal for a long time. [0003] There are many diseases that cause throat ulcers, and the reasons are different. Except for some special infections (diphtheria, tuberculosis, syphilis, induration, etc.) and pharyngeal tumors, pharyngeal ulcers are generally caused by pharyngitis. It will involve earache or even mandibular pain, collarbone or even pain in the back of t...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61K9/06A61P11/04A61K31/245
Inventor 孙洁石杰苏家茹王兰英史文毅
Owner QINGDAO MUNICIPAL HOSPITAL
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